Chordin-like protein 1 promotes neuronal differentiation by inhibiting bone morphogenetic protein-4 in neural stem cells

Molecular Medicine Reports

Volumn 7, Issue 4, 2013, Pages 1143-1148

  Gao, Wei Lu ^a   Zhang, Sheng Quan ^a   Zhang, Hui ^a   Wan, Bo ^b   Yin, Zong Sheng ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Hefei Third People's Hospital   (China)

Author keywords

Cell differentiation; Chordin like protein 1; Gene expression; Neural stem cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CHORDIN; CHORDIN LIKE PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; CULTURE MEDIUM; GENE OVEREXPRESSION; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; SPINAL CORD; WESTERN BLOTTING;

ANIMALS; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; EYE PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEURONS; RATS; SPINAL CORD;

EID: 84875277811     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1310     Document Type: Article

References (33)

1. Willerth SM and Sakiyama-Elbert SE: Cell therapy for spinal cord regeneration. Adv Drug Deliv Rev 60: 263-276, 2008.
2. Hill CE, Proschel C, Noble M, Mayer-Proschel M, Gensel JC, Beattie MS and Bresnahan JC: Acute transplantation of glial-restricted precursor cells into spinal cord contusion injuries: survival, differentiation and effects on lesion environment and axonal regeneration. Exp Neurol 190: 289-310, 2004.
3. Enzmann GU, Benton RL, Woock JP, Howard RM, Tsoulfas P and Whittemore SR: Consequences of noggin expression by neural stem, glial and neuronal precursor cells engrafted into the injured spinal cord. Exp Neurol 195: 293-304, 2005.
4. Roy NS, Cleren C, Singh SK, Yang L, Beal MF and Goldman SA: Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes. Nat Med 12: 1259-1268, 2006.
5. McDonald JW, Liu XZ, Qu Y, et al: Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord. Nat Med 5: 1410-1412, 1999.
6. Ma H, Yu B, Kong L, Zhang Y and Shi Y: Transplantation of neural stem cells enhances expression of synaptic protein and promotes functional recovery in a rat model of traumatic brain injury. Mol Med Rep 4: 849-856, 2011.
7. Kulbatski I, Mothe AJ, Nomura H and Tator CH: Endogenous and exogenous CNS derived stem/progenitor cell approaches for neurotrauma. Curr Drug Targets 6: 111-126, 2005.
8. Galvin KA and Jones DG: Adult human neural stem cells for cell-replacement therapies in the central nervous system. Med J Aust 177: 316-318, 2002.
9. Martens DJ, Seaberg RM and Van der Kooy D: In vivo infusions of exogenous growth factors into the fourth ventricle of the adult mouse brain increase the proliferation of neural progenitors around the fourth ventricle and the central canal of the spinal cord. Eur J Neurosci 16: 1045-1057, 2002.
10. Sailor KA, Ming GL and Song H: Neurogenesis as a potential therapeutic strategy for neurodegenerative diseases. Expert Opin Biol Ther 6: 879-890, 2006.
11. Goldman SA: Directed mobilization of endogenous neural progenitor cells: the intersection of stem cell biology and gene therapy. Curr Opin Mol Ther 6: 466-472, 2004.
12. Johansson CB, Momma S, Clarke DL, Risling M, Lendahi U and Frisen J: Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96: 25-34, 1999.
13. Schwab ME: Repairing the injured spinal cord. Science 295: 1029-1031, 2002.
14. Dobkin BH and Havton LA: Basic advances and new avenues in therapy of spinal cord injury. Annu Rev Med 55: 255-282, 2004.
15. Alexanian AR, Kwob WM, Pravdic D, Maiman DJ and Fehlings MG: Survival of neurally induced mesenchymal cells may determine degree of motor recovery in injured spinal cord rats. Restor Neurol Neurosci 28: 761-767, 2010.
16. Mabie PC, Mehler MF, Marmur R, Papavasiliou A, Song Q and Kessler JA: Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial-astroglial progenitor cells. J Neurosci 17: 4112-4120, 1997.
17. Mehler MF, Mabie PC, Zhu G, Gokhan S and Kessler JA: Developmental changes in progenitor cell responsiveness to bone morphogenetic proteins differentially modulate progressive CNS lineage fate. Dev Neurosci 22: 74-85, 2000.
18. Nakajima T, Ota M and Ito K: Differentiations of autonomic neurons by BMP-independent mechanisms. Cell Tissue Res 332: 25-35, 2008.
19. Blitz IL and Cho KW: Finding partners: how BMPs select their targets. Dev Dyn 238: 1321-1331, 2009.
20. Ueki T, Tanaka M, Yamashita K, et al: A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampus. J Neurosci 23: 11732-11740, 2003.
21. Sakuta H, Suzuki R, Takahashi H, et al: Ventroptin: a BMP-4 antagonist expressed in a double-gradient pattern in the retina. Science 293: 111-115, 2001.
22. Yin ZS, Zhang H, Wang W, Hua XY, Hu Y, Zhang SQ and Li GW: Wnt-3a protein promote neuronal differentiation of neural stem cells derived from adult mouse spinal cord. Neurol Res 29: 847-854, 2007.
23. Xiao Q, Du Y, Wu W and Yip HK: Bone morphogenetic proteins mediate cellular response and, together with Noggin, regulate astrocyte differentiation after spinal cord injury. Exp Neurol 221: 353-366, 2010.
24. Nakashima K, Takizawa T, Ochiai W, et al: BMP2-mediated alteration in the developmental pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA 98: 5868-5873, 2001.
25. Yanagisawa M, Takizawa T, Ochiai W, Uemura A, Nakashima K and Taga T: Fate alternation of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins. Neurosci Res 41: 391-396, 2001.
26. Mehler MF, Mabie PC, Zhang D and Kessler JA: Bone morphogenetic proteins in the nervous system. Trends Neurosci 20: 309-317, 1997.
27. Li W, Cogswell CA and LoTurco JJ: Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP. J Neurosci 18: 8853-8862, 1998.
28. Mabie PC, Mehler MF and Kessle JA: Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype. J Neurosci 19: 7077-7088, 1999.
29. Lim DA, Tramontin AD, Trevejo JM, Herrera DG, Garcia-Verdugo JM and Alvarez-Buylla A: Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28: 713-726, 2000.
30. Shakèd M, Weissmüller K, Svoboda H, Hortschansky P, Nishino N, Wölfl S and Tucker KL: Histone deacetylases control neurogenesis in embryonic brain inhibition of BMP2/4 signaling. PLoS One 3: e2668, 2008.
31. Weible MW II and Chan-Ling T: Phenotypic characterization of neural stem cells from human fetal spinal cord: synergistic effect of LIF and BMP4 to generate astrocytes. Glia 55: 1156-1168, 2007.
32. Sasai Y: Regulation of neural determination by evolutionarily conserved signals: anti-BMP factors and what next? Curr Opin Neurobiol 11: 22-26, 2001.
33. Fu SL, Ma ZW, Yin L, Iannotti C, Lu PH and Xu XM: Region-specific growth properties and trophic requirements of brain-and spinal cord-derived rat embryonic neural precursor cells. Neuroscience 135: 851-862, 2005.