Autophagy protects type II alveolar epithelial cells from Mycobacterium tuberculosis infection

Biochemical and Biophysical Research Communications

Volumn 432, Issue 2, 2013, Pages 308-313

  Guo, Xu Guang ^a,b   Ji, Tian Xing ^b   Xia, Yong ^b   Ma, Yue Yun ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

A549 cells; Apoptosis; Autophagy; Mycobacterium tuberculosis; Type II alveolar epithelial cells

Indexed keywords

3 METHYLADENINE; AUTOPHAGY PROTEIN 5; LACTATE DEHYDROGENASE; MESSENGER RNA; SMALL INTERFERING RNA;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL COMPARTMENTALIZATION; CELL DEATH; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME RELEASE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; LUNG ALVEOLUS EPITHELIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TUBERCULOSIS;

AUTOPHAGY; CELL LINE; GENE KNOCKDOWN TECHNIQUES; HUMANS; L-LACTATE DEHYDROGENASE; MICROTUBULE-ASSOCIATED PROTEINS; MYCOBACTERIUM TUBERCULOSIS; PNEUMOCYTES; RNA, SMALL INTERFERING; TUBERCULOSIS, PULMONARY;

BACILLI (CLASS); MYCOBACTERIUM TUBERCULOSIS;

EID: 84875276269     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.01.111     Document Type: Article

References (28)

1. Ligon L.S., Hayden J.D., Braunstein M. The ins and outs of Mycobacterium tuberculosis protein export. Tuberculosis (Edinb.) 2012, 92:121-132.
2. Huynh K.K., Joshi S.A., Brown E.J. A delicate dance: host response to Mycobacteria. Curr. Opin. Immunol. 2011, 23:464-472.
3. Fehrenbach H. Alveolar epithelial type II cell: defender of the alveolus revisited. Respir. Res. 2001, 2:33-46.
4. Bermudez L.E., Goodman J. Mycobacterium tuberculosis invades and replicates within type II alveolar cells. Infect. Immun. 1996, 64:1400-1406.
5. Birkness K.A., Deslauriers M., Bartlett J.H., White E.H., King C.H., Quinn F.D. An in vitro tissue culture bilayer model to examine early events in Mycobacterium tuberculosis infection. Infect. Immun. 1999, 67:653-658.
6. Mehta P.K., King C.H., White E.H., Murtagh J.J., Quinn F.D. Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication. Infect. Immun. 1996, 64:2673-2679.
7. Sato K., Akaki T., Shimizu T., Sano C., Ogasawara K., Tomioka H. Invasion and intracellular growth of Mycobacterium tuberculosis and Mycobacterium avium complex adapted to intramacrophagic environment within macrophages and type II alveolar epithelial cells. Kekkaku 2001, 76:53-57.
8. McDonough K.A., Kress Y. Cytotoxicity for lung epithelial cells is a virulence-associated phenotype of Mycobacterium tuberculosis. Infect. Immun. 1995, 63:4802-4811.
9. McClean S., Callaghan M. Burkholderia cepacia complex: epithelial cell-pathogen confrontations and potential for therapeutic intervention. J. Med. Microbiol. 2009, 58:1-12.
10. Bauman S.J., Kuehn M.J. Pseudomonas aeruginosa vesicles associate with and are internalized by human lung epithelial cells. BMC Microbiol. 2009, 9:26.
11. Espert L., Codogno P., Biard-Piechaczyk M. Involvement of autophagy in viral infections: antiviral function and subversion by viruses. J. Mol. Med. (Berl.) 2007, 85:811-823.
12. Gutierrez M.G., Master S.S., Singh S.B., Taylor G.A., Colombo M.I., Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004, 119:753-766.
13. Schmid D., Dengjel J., Schoor O., Stevanovic S., Munz C. Autophagy in innate and adaptive immunity against intracellular pathogens. J. Mol. Med. (Berl.) 2006, 84:194-202.
14. Alonso S., Pethe K., Russell D.G., Purdy G.E. Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagy. Proc. Natl. Acad. Sci. USA 2007, 104:6031-6036.
15. Yang Y.P., Liang Z.Q., Gu Z.L., Qin Z.H. Molecular mechanism and regulation of autophagy. Acta Pharmacol. Sin. 2005, 26:1421-1434.
16. Levine B., Yuan J. Autophagy in cell death: an innocent convict?. J. Clin. Invest. 2005, 115:2679-2688.
17. Nakagawa I., Amano A., Mizushima N., Yamamoto A., Yamaguchi H., Kamimoto T., Nara A., Funao J., Nakata M., Tsuda K., Hamada S., Yoshimori T. Autophagy defends cells against invading group A Streptococcus. Science 2004, 306:1037-1040.
18. Smith I. Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence. Clin. Microbiol. Rev. 2003, 16:463-496.
19. Foster K.A., Oster C.G., Mayer M.M., Avery M.L., Audus K.L. Characterization of the A549 cell line as a type II pulmonary epithelial cell model for drug metabolism. Exp. Cell. Res. 1998, 243:359-366.
20. Deretic V., Levine B. Autophagy, immunity, and microbial adaptations. Cell Host Microbe 2009, 5:527-549.
21. Blommaart E.F., Krause U., Schellens J.P., Vreeling-Sindelarova H., Meijer A.J. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur. J. Biochem. 1997, 243:240-246.
22. Shacka J.J., Klocke B.J., Roth K.A. Autophagy, bafilomycin and cell death: the "a-B-cs" of plecomacrolide-induced neuroprotection. Autophagy 2006, 2:228-230.
23. Xing C., Zhu B., Liu H., Yao H., Zhang L. Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901. Acta Biochim. Biophys. Sin. (Shanghai) 2008, 40:194-201.
24. Backer J.M. The regulation and function of Class III PI3Ks: novel roles for Vps34. Biochem. J. 2008, 410:1-17.
25. Xue L., Borutaite V., Tolkovsky A.M. Inhibition of mitochondrial permeability transition and release of cytochrome c by anti-apoptotic nucleoside analogues. Biochem. Pharmacol. 2002, 64:441-449.
26. Liu Y., Schiff M., Czymmek K., Talloczy Z., Levine B., Dinesh-Kumar S.P. Autophagy regulates programmed cell death during the plant innate immune response. Cell 2005, 121:567-577.
27. Orvedahl A., MacPherson S., Sumpter R., Talloczy Z., Zou Z., Levine B. Autophagy protects against Sindbis virus infection of the central nervous system. Cell Host Microbe 2010, 7:115-127.
28. Zhao Z., Fux B., Goodwin M., Dunay I.R., Strong D., Miller B.C., Cadwell K., Delgado M.A., Ponpuak M., Green K.G., Schmidt R.E., Mizushima N., Deretic V., Sibley L.D., Virgin H.W. Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host Microbe 2008, 4:458-469.