The neurobehavioral impact of manganese: Results and challenges obtained by a meta-analysis of individual participant data

NeuroToxicology

Volumn 36, Issue , 2013, Pages 1-9

  Meyer Baron, Monika ^a   Schäper, Michael ^a   Knapp, Guido ^b   Lucchini, Roberto ^c,p   Zoni, Silvia ^c   Bast Pettersen, Rita ^d   Ellingsen, Dag G ^d   Thomassen, Yngvar ^d   He, Shuchang ^e   Yuan, Hong ^e   Niu, Qiao ^f   Wang, Xian liang ^g   Yang, Yong jian ^h   Iregren, Anders ⁱ   Sjögren, Bengt ^j   Blond, Morten ^k   Laursen, Peter ^l   Netterstrom, Bo ^m   Mergler, Donna ⁿ   Bowler, Rosemarie ^o   van Thriel, Christoph ^a   more..

^a LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

^b TU DORTMUND UNIVERSITY   (Germany)

^c UNIVERSITY OF BRESCIA   (Italy)

^d NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^e PEKING UNIVERSITY   (China)

^f SHANXI MEDICAL UNIVERSITY   (China)

^g CHINESE RESEARCH ACADEMY OF ENVIRONMENTAL SCIENCES   (China)

^h ANHUI MEDICAL UNIVERSITY   (China)

ⁱ Swedish Work Environment Authority   (Sweden)

^j KAROLINSKA INSTITUTE   (Sweden)

^k Clinic of Occupational Medicine   (Denmark)

^l Danish Working Environment Authority   (Denmark)

^m BISPEBJERG HOSPITAL   (Denmark)

ⁿ UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^o SAN FRANCISCO STATE UNIVERSITY   (United States)

^p MOUNT SINAI SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Biomarker; Neurobehavioral toxicology; Neurobiological model; Neuropsychological test; Systematic review

Indexed keywords

MANGANESE;

ATTENTION DISTURBANCE; BLOOD LEVEL; COGNITION; HUMAN; MEMORY DISORDER; MOTOR PERFORMANCE; NEUROPSYCHOLOGICAL TEST; NEUROTOXICITY; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; RESPONSE TIME; REVIEW; SHORT TERM MEMORY;

ANALYSIS OF VARIANCE; COGNITION DISORDERS; DATABASES, BIBLIOGRAPHIC; HUMANS; MANGANESE; MANGANESE POISONING; NEUROPSYCHOLOGICAL TESTS;

EID: 84875260661     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2013.02.003     Document Type: Review

References (71)

1. Alexander G.E., Crutcher M.D. Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 1990, 13(7):266-271.
2. Alexander G.E., DeLong M.R., Strick P.L. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 1986, 9:357-381.
3. Arbuthnott K., Frank J. Trail making test, part B as a measure of executive control: validation using a set-switching paradigm. J Clin Exp Neuropsychol 2000, 22(4):518-528.
4. Bast-Pettersen R., Ellingsen D.G., Hetland S.M., Thomassen Y. Neuropsychological function in manganese alloy plant workers. Int Arch Occup Environ Health 2004, 77(4):277-287.
5. Beste C., Baune B.T., Domschke K., Falkenstein M., Konrad C. Dissociable influences of NR2B-receptor related neural transmission on functions of distinct associative basal ganglia circuits. Neuroimage 2010, 52(1):309-315.
6. Beste C., Dziobek I., Hielscher H., Willemssen R., Falkenstein M. Effects of stimulus-response compatibility on inhibitory processes in Parkinson's disease. Eur J Neurosci 2009, 29(4):855-860.
7. Beste C., Willemssen R., Saft C., Falkenstein M. Error processing in normal aging and in basal ganglia disorders. Neuroscience 2009, 159(1):143-149.
8. Blond M., Netterstrom B. Neuromotor function in a cohort of Danish steel workers. Neurotoxicology 2007, 28(2):336-344.
9. Blond M., Netterstrom B., Laursen P. Cognitive function in a cohort of Danish steel workers. Neurotoxicology 2007, 28(2):328-335.
10. Bowler R.M., Roels H.A., Nakagawa S., Drezgic M., Diamond E., Park R., et al. Dose-effect relationships between manganese exposure and neurological, neuropsychological and pulmonary function in confined space bridge welders. Occup Environ Med 2007, 64(3):167-177.
11. Brenneman K.A., Wong B.A., Buccellato M.A., Costa E.R., Gross E.A., Dorman D.C. Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: toxicokinetic investigations in a unilateral nasal occlusion model. Toxicol Appl Pharmacol 2000, 169(3):238-248.
12. Cervilla J.A., Prince M., Joels S., Lovestone S., Mann A. Long-term predictors of cognitive outcome in a cohort of older people with hypertension. Br J Psychiatry 2000, 177:66-71.
13. Chang Y., Kim Y., Woo S.T., Song H.J., Kim S.H., Lee H., et al. High signal intensity on magnetic resonance imaging is a better predictor of neurobehavioral performances than blood manganese in asymptomatic welders. Neurotoxicology 2009, 30(4):555-563.
14. Chia S.E., Foo S.C., Gan S.L., Jeyaratnam J., Tian C.S. Neurobehavioral functions among workers exposed to manganese ore. Scand J Work Environ Health 1993, 19(4):264-270.
15. Chudasama Y., Robbins T.W. Functions of frontostriatal systems in cognition: comparative neuropsychopharmacological studies in rats, monkeys and humans. Biol Psychol 2006, 73(1):19-38.
16. Biological markers in environmental health research. Environ Health Perspect 1987, 74:3-9. Committee on Biological Markers of the National Research Council.
17. Couper J. On the effects of black oxide of manganese when inhaled into the lungs. Br Ann Med Pharmacol 1837, 1:41-42.
18. Cowan D.M., Fan Q., Zou Y., Shi X., Chen J., Aschner M., et al. Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment. Biomarkers 2009, 14(1):3-16.
19. Cowan D.M., Zheng W., Zou Y., Shi X., Chen J., Rosenthal F.S., et al. Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations. Neurotoxicology 2009, 30(6):1214-1222.
20. Criswell S.R., Perlmutter J.S., Videen T.O., Moerlein S.M., Flores H.P., Birke A.M., et al. Reduced uptake of [(1)F]FDOPA PET in asymptomatic welders with occupational manganese exposure. Neurology 2011, 76(15):1296-1301.
21. Curran P.J., Hussong A.M. Integrative data analysis: the simultaneous analysis of multiple data sets. Psychol Methods 2009, 14(2):81-100.
22. Dawson D.A. Methodological issues in measuring alcohol use. Alcohol Res Health 2003, 27(1):18-29.
23. Del Boca F.K., Darkes J. The validity of self-reports of alcohol consumption: state of the science and challenges for research. Addiction 2003, 98(Suppl. 2):1-12.
24. Ellingsen D.G., Konstantinov R., Bast-Pettersen R., Merkurjeva L., Chashchin M., Thomassen Y., et al. A neurobehavioral study of current and former welders exposed to manganese. Neurotoxicology 2008, 29(1):48-59.
25. Eriksson H., Tedroff J., Thuomas K.A., Aquilonius S.M., Hartvig P., Fasth K.J., et al. Manganese induced brain lesions in Macaca fascicularis as revealed by positron emission tomography and magnetic resonance imaging. Arch Toxicol 1992, 66(6):403-407.
26. Fleming M.D., Romano M.A., Su M.A., Garrick L.M., Garrick M.D., Andrews N.C. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A 1998, 95(3):1148-1153.
27. Hazy T.E., Frank M.J., O'Reilly R.C. Towards an executive without a homunculus: computational models of the prefrontal cortex/basal ganglia system. Philos Trans R Soc Lond Ser B: Biol Sci 2007, 362(1485):1601-1613.
28. Hedden T., Gabrieli J.D.E. Insights into the ageing mind: a view from cognitive neuroscience. Nat Rev Neurosci 2004, 5:85-97.
29. Humphries M.D., Stewart R.D., Gurney K.N. A physiologically plausible model of action selection and oscillatory activity in the basal ganglia. J Neurosci 2006, 26(50):12921-12942.
30. Jiang Y., Zheng W., Long L., Zhao W., Li X., Mo X., et al. Brain magnetic resonance imaging and manganese concentrations in red blood cells of smelting workers: search for biomarkers of manganese exposure. Neurotoxicology 2007, 28(1):126-135.
31. Kim E., Kim Y., Cheong H.K., Cho S., Shin Y.C., Sakong J., et al. Pallidal index on MRI as a target organ dose of manganese: structural equation model analysis. Neurotoxicology 2005, 26(3):351-359.
32. Kim E.A., Cheong H.K., Choi D.S., Sakong J., Ryoo J.W., Park I., et al. Effect of occupational manganese exposure on the central nervous system of welders: 1H magnetic resonance spectroscopy and MRI findings. Neurotoxicology 2007, 28(2):276-283.
33. Kim Y., Kim K.S., Yang J.S., Park I.J., Kim E., Jin Y., et al. Increase in signal intensities on T1-weighted magnetic resonance images in asymptomatic manganese-exposed workers. Neurotoxicology 1999, 20(6):901-907.
34. Lambert P.C., Sutton A.J., Abrams K.R., Jones D.R. A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis. J Clin Epidemiol 2002, 55(1):86-94.
35. Langenecker S.A., Zubieta J.K., Young E.A., Akil H., Nielson K.A. A task to manipulate attentional load, set-shifting, and inhibitory control: convergent validity and test-retest reliability of the Parametric Go/No-Go Test. J Clin Exp Neuropsychol 2007, 29(8):842-853.
36. Lucchini R., Apostoli P., Perrone C., Placidi D., Albini E., Migliorati P., et al. Long term exposure to low levels of manganese oxides and neurofunctional changes in ferroalloy workers. Neurotoxicology 1999, 20(2-3):287-298.
37. Lucchini R., Bergamaschi E., Smargiassi A., Festa D., Apostoli P. Motor function, olfactory threshold, and hematological indices in manganese-exposed ferroalloy workers. Environ Res 1997, 73(1-2):175-180.
38. Lucchini R., Selis L., Folli D., Apostoli P., Mutti A., Vanoni O., et al. Neurobehavioral effects of manganese in workers from a ferroalloy plant after temporary cessation of exposure. Scand J Work Environ Health 1995, 21:143-149.
39. Lucchini R.G., Guazzetti S., Zoni S., Donna F., Peter S., Zacco A., et al. Tremor, olfactory and motor changes in Italian adolescents exposed to historical ferro-manganese emission. Neurotoxicology 2012, 33(4):687-696.
40. McCabe D.P., Roediger H.L., McDaniel M.A., Balota D.A., Hambrick D.Z. The relationship between working memory capacity and executive functioning: evidence for a common executive attention construct. Neuropsychology 2010, 24(2):222-243.
41. McElvenny D.M., Armstrong B.G., Jarup L., Higgins J.P. Meta-analysis in occupational epidemiology: a review of practice. Occup Med (Lond) 2004, 54(5):336-344.
42. Meltzer H.M., Brantsaeter A.L., Borch-Iohnsen B., Ellingsen D.G., Alexander J., Thomassen Y., et al. Low iron stores are related to higher blood concentrations of manganese, cobalt and cadmium in non-smoking, Norwegian women in the HUNT 2 study. Environ Res 2010, 110(5):497-504.
43. Mercier M.J., Robinson A.E. Use of biologic markers for toxic end-points in assessment of risks from exposure to chemicals. Int Arch Occup Environ Health 1993, 65(1 Suppl.):S7-S10.
44. Mergler D., Baldwin M., Belanger S., Larribe F., Beuter A., Bowler R., et al. Manganese neurotoxicity, a continuum of dysfunction: results from a community based study. Neurotoxicology 1999, 20(2-3):327-342.
45. Mergler D., Huel G., Bowler R., Iregren A., Belanger S., Baldwin M., et al. Nervous system dysfunction among workers with long-term exposure to manganese. Environ Res 1994, 64(2):151-180.
46. Meyer-Baron M., Knapp G., Schaper M., van Thriel C. Performance alterations associated with occupational exposure to manganese - a meta-analysis. Neurotoxicology 2009, 30(4):487-496.
47. Meyer-Baron M., Schaper M., Knapp G., Lucchini R., Albini E., Bast-Pettersen R., et al. Statistical means to enhance the comparability of data within a pooled analysis of individual data in neurobehavioral toxicology. Toxicol Lett 2011, 206(2):144-151.
48. Myers J.E., Thompson M.L., Ramushu S., Young T., Jeebhay M.F., London L., et al. The nervous system effects of occupational exposure on workers in a South African manganese smelter. Neurotoxicology 2003, 24(6):885-894.
49. Newland M.C. Animal models of manganese's neurotoxicity. Neurotoxicology 1999, 20(2-3):415-432.
50. Newland M.C., Ceckler T.L., Kordower J.H., Weiss B. Visualizing manganese in the primate basal ganglia with magnetic resonance imaging. Exp Neurol 1989, 106(3):251-258.
51. Newland M.C., Cox C., Hamada R., Oberdorster G., Weiss B. The clearance of manganese chloride in the primate. Fundam Appl Toxicol 1987, 9(2):314-328.
52. Newland M.C., Weiss B. Persistent effects of manganese on effortful responding and their relationship to manganese accumulation in the primate globus pallidus. Toxicol Appl Pharmacol 1992, 113(1):87-97.
53. Pesch B., Weiss T., Kendzia B., Henry J., Lehnert M., Lotz A., et al. Levels and predictors of airborne and internal exposure to manganese and iron among welders. J Expo Sci Environ Epidemiol 2012, 22(3):291-298.
54. Riojas-Rodriguez H., Solis-Vivanco R., Schilmann A., Montes S., Rodriguez S., Rios C., et al. Intellectual function in Mexican children living in a mining area and environmentally exposed to manganese. Environ Health Perspect 2010, 118(10):1465-1470.
55. Rodriguez-Agudelo Y., Riojas-Rodriguez H., Rios C., Rosas I., Sabido Pedraza E., Miranda J., et al. Motor alterations associated with exposure to manganese in the environment in Mexico. Sci Total Environ 2006, 368(2-3):542-556.
56. Saint-Cyr J.A. Frontal-striatal circuit functions: context, sequence, and consequence. J Int Neuropsychol Soc 2003, 9(1):103-127.
57. Sanchez-Cubillo I., Perianez J.A., Adrover-Roig D., Rodriguez-Sanchez J.M., Rios-Lago M., Tirapu J., et al. Construct validity of the Trail Making Test: role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. J Int Neuropsychol Soc 2009, 15(3):438-450.
58. Schmand B., Smit J.H., Geerlings M.I., Lindeboom J. The effects of intelligence and education on the development of dementia. A test of the brain reserve hypothesis. Psychol Med 1997, 27(6):1337-1344.
59. Siegl P., Bergert K.D. A method of early diagnostic monitoring in manganese exposure. Z Gesamte Hyg 1982, 28(8):524-526.
60. Silbergeld E.K., Davis D.L. Role of biomarkers in identifying and understanding environmentally induced disease. Clin Chem 1994, 40(7 Pt. 2):1363-1367.
61. Sjögren B., Iregren A., Frech W., Hagman M., Johansson L., Tesarz M., et al. Effects on the nervous system among welders exposed to aluminium and manganese. Occup Environ Med 1996, 53:32-40.
62. Stewart L.A., Tierney J.F. To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data. Eval Health Prof 2002, 25(1):76-97.
63. Takeda A., Sawashita J., Okada S. Biological half-lives of zinc and manganese in rat brain. Brain Res 1995, 695(1):53-58.
64. Thompson K.J., Molina R.M., Donaghey T., Savaliya S., Schwob J.E., Brain J.D. Manganese uptake and distribution in the brain after methyl bromide-induced lesions in the olfactory epithelia. Toxicol Sci 2011, 120(1):163-172.
65. Wang X., Yang Y., Wang X., Xu S. The effect of occupational exposure to metals on the nervous system function in welders. J Occup Health 2006, 48(2):100-106.
66. Wasserman G.A., Liu X., Parvez F., Factor-Litvak P., Ahsan H., Levy D., et al. Arsenic and manganese exposure and children's intellectual function. Neurotoxicology 2011, 32(4):450-457.
67. Wastensson G., Sallsten G., Bast-Pettersen R., Barregard L. Neuromotor function in ship welders after cessation of manganese exposure. Int Arch Occup Environ Health 2012, 85(6):703-713.
68. Willemssen R., Falkenstein M., Schwarz M., Muller T., Beste C. Effects of aging, Parkinson's disease, and dopaminergic medication on response selection and control. Neurobiol Aging 2011, 32(2):327-335.
69. Willemssen R., Muller T., Schwarz M., Falkenstein M., Beste C. Response monitoring in de novo patients with Parkinson's disease. PloS one 2009, 4(3):e4898.
70. Yuan H., He S., He M., Niu Q., Wang L., Wang S. A comprehensive study on neurobehavior, neurotransmitters and lymphocyte subsets alteration of Chinese manganese welding workers. Life Sci 2006, 78(12):1324-1328.
71. Zheng W., Kim H., Zhao Q. Comparative toxicokinetics of manganese chloride and methylcyclopentadienyl manganese tricarbonyl (MMT) in Sprague-Dawley rats. Toxicol Sci 2000, 54(2):295-301.