The Near-Road Exposures and Effects of Urban Air Pollutants Study (NEXUS): Study design and methods

Science of the Total Environment

Volumn 448, Issue , 2013, Pages 38-47

  Vette, Alan ^a   Burke, Janet ^a   Norris, Gary ^a   Landis, Matthew ^a   Batterman, Stuart ^b   Breen, Michael ^a   Isakov, Vlad ^a   Lewis, Toby ^d   Gilmour, M Ian ^c   Kamal, Ali ^a   Hammond, Davyda ^a,e   Vedantham, Ram ^a   Bereznicki, Sarah ^a   Tian, Nancy ^a   Croghan, Carry ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e Germanna Community College   (United States)

Author keywords

Asthmatic children; Human exposure; Indoor air; Respiratory outcomes; Source receptor relationships; Traffic air pollution

Indexed keywords

ASTHMATIC CHILDREN; HUMAN EXPOSURES; INDOOR AIR; RESPIRATORY OUTCOMES; SOURCE-RECEPTOR RELATIONSHIPS;

AIR QUALITY; CARBON MONOXIDE; DESIGN; ROADS AND STREETS;

DISEASES;

BLACK CARBON; CARBON MONOXIDE; NITRIC OXIDE; NITROGEN DIOXIDE;

AIR QUALITY; ASTHMA; ATMOSPHERIC POLLUTION; CHILD HEALTH; HEALTH IMPACT; MODEL TEST; NITROGEN OXIDES; POLLUTION EFFECT; POLLUTION EXPOSURE; URBAN POLLUTION;

ADVERSE OUTCOME; AIR MONITORING; AIR POLLUTION; AIR QUALITY; ARTICLE; ASTHMA; ENVIRONMENTAL EXPOSURE; EXHAUST GAS; INFLAMMATION; OXIDATIVE STRESS; PARTICIPATORY RESEARCH; PARTICULATE MATTER; PRIORITY JOURNAL; SCHOOL; UNITED STATES; URBAN AREA; VIRAL RESPIRATORY TRACT INFECTION;

ADOLESCENT; AIR POLLUTANTS; ASTHMA; BIOLOGICAL MARKERS; CELLS, CULTURED; CHILD; CITIES; COHORT STUDIES; ENVIRONMENTAL MONITORING; HUMANS; INFLAMMATION; MICHIGAN; MODELS, THEORETICAL; MOTOR VEHICLES; RESPIRATORY TRACT INFECTIONS; SOOT; VEHICLE EMISSIONS;

DETROIT; MICHIGAN; UNITED STATES;

EID: 84875251737     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2012.10.072     Document Type: Article

References (56)

1. Adar S.D., Gold D.R., Coull B.A., Schwartz J., Stone P.H., Suh H. Focused exposures to airborne traffic particles and heart rate variability in the elderly. Epidemiology 2007, 18:95-103.
2. Anderson H., Favarato G., Atkinson R. Long-term exposure to air pollution and the incidence of asthma: meta-analysis of cohort studies. Air Qual Atmos Health 2011, 1-10.
3. Baldauf R., Thoma E., Hays M., Shores R., Kinsey J., Gullett B., et al. Traffic and meteorological impacts on near-road air quality: summary of methods and trends from the raleigh near-road study. J Air Waste Manag Assoc 2008, 58:865-878.
4. Barzyk T.M., George B.J., Vette A.F., Williams R.W., Croghan C.W., Stevens C.D. Development of a distance-to-roadway proximity metric to compare near-road pollutant levels to a central site monitor. Atmos Environ 2009, 43:787-797.
5. Brauer M., Hoek G., Van Vliet P., Meliefste K., Fischer P.H., Wijga A., et al. Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children. Am J Respir Crit Care Med 2002, 166:1092-1098.
6. Brauer M., Lencar C., Tamburic L., Koehoorn M., Demers P., Karr C. A cohort study of traffic-related air pollution impacts on birth outcomes. Environ Health Perspect 2008, 116:680-686.
7. Breen M.S., Breen M., Williams R.W., Schultz B.D. Predicting residential air exchange rates from questionnaires and meteorology: model evaluation in central north carolina. Environ Sci Technol 2010, 44:9349-9356.
8. Brunekreef B., Janssen N.A.H., deHartog J., Harssema H., Knape M., vanVliet P. Air pollution from truck traffic and lung function in children living near motorways. Epidemiology 1997, 8:298-303.
9. Cimorelli A.J., Perry S.G., Venkatram A., Weil J.C., Paine R.J., Wilson R.B., et al. AERMOD: a dispersion model for industrial source applications. Part I: general model formulation and boundary layer characterization. J Appl Meteorol 2005, 44:682-693.
10. Clark N.A., Demers P.A., Karr C.J., Koehoorn M., Lencar C., Tamburic L., et al. Effect of early life exposure to air pollution on development of childhood asthma. Environ Health Perspect 2010, 118:284-290.
11. Cook R., Isakov V., Touma J.S., Benjey W., Thurman J., Kinnee E., et al. Resolving local-scale emissions for modeling air quality near roadways. J Air Waste Manag Assoc 2008, 58:451-461.
12. Demokritou P., Kavouras I.G., Ferguson S.T., Koutrakis P. Development of a high volume cascade impactor for toxicological and chemical characterization studies. Aerosol Sci Technol 2002, 36:925-933.
13. 2.5 source impacts across Detroit, MI. Atmos Environ 2012, 47:491-498.
14. Garshick E., Laden F., Hart J.E., Caron A. Residence near a major road and respiratory symptoms in US veterans. Epidemiology 2003, 14:728-736.
15. Gauderman W.J., Vora H., McConnell R., Berhane K., Gilliland F., Thomas D., et al. Effect of exposure to traffic on lung development from 10 to 18years of age: a cohort study. Lancet 2007, 369:571-577.
16. Gehring U., Cyrys J., Sedlmeir G., Brunekreef B., Bellander T., Fischer P., et al. Traffic-related air pollution and respiratory health during the first 2yrs of life. Eur Respir J 2002, 19:690-698.
17. 2.5 samples. Atmos Environ 2004, 38:237-247.
18. Hagler G.S.W., Baldauf R.W., Thoma E.D., Long T.R., Snow R.F., Kinsey J.S., et al. Ultrafine particles near a major roadway in Raleigh, North Carolina: downwind attenuation and correlation with traffic-related pollutants. Atmos Environ 2009, 43:1229-1234.
19. Hammond D.M., Dvonch J.T., Keeler G.J., Parker E.A., Kamal A.S., Barres J.A., et al. Sources of ambient fine particulate matter at two community sites in Detroit, Michigan. Atmos Environ 2008, 42:720-732.
20. HEI Panel on the health effects of traffic-related air pollution, traffic-related air pollution: a critical review of the literature on emissions, exposure, and health effects. HEI Special Report 17 2009, Health Effects Institute, Boston, MA.
21. Henry R.C., Vette A., Norris G., Vedantham R., Kimbrough S., Shores R.C. Separating the air quality impact of a major highway and nearby sources by nonparametric trajectory analysis. Environ Sci Technol 2011, 45:10471-10476.
22. Hu S.S., Fruin S., Kozawa K., Mara S., Paulson S.E., Winer A.M. A wide area of air pollutant impact downwind of a freeway during pre-sunrise hours. Atmos Environ 2009, 43:2541-2549.
23. Isakov V., Touma J.S., Burke J., Lobdell D.T., Palma T., Rosenbaum A., et al. Combining regional- and local-scale air quality models with exposure models for use in environmental health studies. J Air Waste Manag Assoc 2009, 59:461-472.
24. Ivy D., Mulholland J.A., Russell A.G. Development of ambient air quality population-weighted metrics for use in time-series health studies. J Air Waste Manag Assoc 2008, 58:711-720.
25. Jerrett M., Arain A., Kanaroglou P., Beckerman B., Potoglou D., Sahsuvaroglu T., et al. A review and evaluation of intraurban air pollution exposure models. J Expo Anal Environ Epidemiol 2005, 15:185-204.
26. Karner A.A., Eisinger D.S., Niemeier D.A. Near-roadway air quality: synthesizing the findings from real-world data. Environ Sci Technol 2010, 44:5334-5344.
27. Kimbrough S., Vallero D., Shores R., Vette A., Black K., Martinez V. Multi-criteria decision analysis for the selection of a near road ambient air monitoring site for the measurement of mobile source air toxics. Transp Res D Transp Environ 2008, 13:505-515.
28. Kittelson D.B., Watts W.F., Johnson J.P. Nanoparticle emissions on Minnesota highways. Atmos Environ 2004, 38:9-19.
29. Kittelson D.B., Watts W.F., Johnson J.P., Remerowki M.L., Ische E.E., Oberdorster G., et al. On-road exposure to highway aerosols. 1. Aerosol and gas measurements. Inhal Toxicol 2004, 16:31-39.
30. Le H.Q., Batterman S.A., Wirth J.J., Wahl R.L., Hoggatt K.J., Sadeghnejad A., et al. Air pollutant exposure and preterm and term small-for-gestational-age births in Detroit, Michigan: long-term trends and associations. Environ Int 2012, 44:7-17.
31. Maheswaran R., Elliott P. Stroke mortality associated with living near main roads in England and Wales - a geographical study. Stroke 2003, 34:2776-2780.
32. Misra C., Kim S., Shen S., Sioutas C. A high flow rate, very low pressure drop impactor for inertial separation of ultrafine from accumulation mode particles. J Aerosol Sci 2002, 33:735-752.
33. Ntziachristos L., Ning Z., Geller M.D., Sioutas C. Particle concentration and characteristics near a major freeway with heavy-duty diesel traffic. Environ Sci Technol 2007, 41:2223-2230.
34. Olson D.A., McDow S.R. Near roadway concentrations of organic source markers. Atmos Environ 2009, 43:2862-2867.
35. Olson D.A., Vedantham R., Norris G.A., Brown S.G., Roberts P. Determining source impacts near roadways using wind regression and organic source markers. Atmos Environ 2012, 47:261-268.
36. Perry S.G., Cimorelli A.J., Paine R.J., Brode R.W., Weil J.C., Venkatram A., et al. AERMOD: a dispersion model for industrial source applications. Part II: model performance against 17 field study databases. J Appl Meteorol 2005, 44:694-708.
37. Peters A., von Klot S., Heier M., Trentinaglia I., Hormann A, Wichmann H.E., et al. Exposure to traffic and the onset of myocardial infarction. N Engl J Med 2004, 351:1721-1730.
38. Phuleria H.C., Sheesley R.J., Schauer J.J., Fine P.M., Sioutas C. Roadside measurements of size-segregated particulate organic compounds near gasoline and diesel-dominated freeways in Los Angeles, CA. Atmos Environ 2007, 41:4653-4671.
39. Ponce N.A., Hoggatt K.J., Wilhelm M., Ritz B. Preterm birth: The interaction of traffic-related air pollution with economic hardship in Los Angeles neighborhoods. Am J Epidemiol 2005, 162:140-148.
40. Reponen T., Grinshpun S.A., Trakumas S., Martuzevicius D., Wang Z.M., LeMasters G., et al. Concentration gradient patterns of aerosol particles near interstate highways in the Greater Cincinnati airshed. J Environ Monit 2003, 5:557-562.
41. Riediker M., Williams R., Devlin R., Griggs T., Bromberg P. Exposure to particulate matter, volatile organic compounds, and other air pollutants inside patrol cars. Environ Sci Technol 2003, 37:2084-2093.
42. Ritz B., Yu F., Chapa G., Fruin S. Effect of air pollution on preterm birth among children born in Southern California between 1989 and 1993. Epidemiology 2000, 11:502-511.
43. Thoma E.D., Shores R.C., Isakov V., Baldauf R.W. Characterization of near-road pollutant gradients using path-integrated optical remote sensing. J Air Waste Manag Assoc 2008, 58:879-890.
44. U.S.Census Bureau Current housing reports, series H150/07, American Housing Survey for the United States 2007, U.S. Government Printing Office, Washington, DC, [20401. Available at http://www.census.gov/prod/2008pubs/h150-07.pdf [accessed 9.4.12]].
45. U.S.EPA Exposure model for individuals (EMI) 2011, U.S. Environmental Protection Agency, Washington, DC, [Available at http://www.epa.gov/heasd/emi [accessed 9.4.12]].
46. U.S.EPA Highway research 2011, U.S. Environmental Protection Agency, Washington, DC, [Available at http://www.epa.gov/airscience/air-highwayresearch.htm [accessed 9.4.12]].
47. Vedantham R., Norris G., Brown S.G., Roberts P. Combining continuous near-road monitoring and inverse modeling to isolate the effect of highway expansion on a school in Las Vegas. Atmos Pollut Res 2012, 3:105-111.
48. Venkatram A., Isakov V., Seila R., Baldauf R. Modeling the impacts of traffic emissions on air toxics concentrations near roadways. Atmos Environ 2009, 43:3191-3199.
49. Vesper S., McKinstry C., Haugland R., Neas L., Hudgens E., Heidenfelder B., et al. Higher environmental relative moldiness index (ERMIsm) values measured in Detroit homes of severely asthmatic children. Sci Total Environ 2008, 394:192-196.
50. Westerdahl D., Fruin S., Sax T., Fine P.M., Sioutas C. Mobile platform measurements of ultrafine particles and associated pollutant concentrations on freeways and residential streets in Los Angeles. Atmos Environ 2005, 39:3597-3610.
51. Wilhelm M., Ritz B. Residential proximity to traffic and adverse birth outcomes in Los Angeles County, California, 1994-1996. Environ Health Perspect 2003, 111:207-216.
52. Williams R., Rea A., Vette A., Croghan C., Whitaker D., Stevens C., et al. The design and field implementation of the Detroit exposure and aerosol research study. J Expo Sci Environ Epidemiol 2009, 19:643-659.
53. Zhou Y., Levy J.I. Factors influencing the spatial extent of mobile source air pollution impacts: a meta-analysis. BMC Public Health 2007, 7.
54. Zhu Y.F., Hinds W.C., Kim S., Sioutas C. Concentration and size distribution of ultrafine particles near a major highway. J Air Waste Manag Assoc 2002, 52:1032-1042.
55. Zhu Y.F., Hinds W.C., Shen S., Sioutas C. Seasonal trends of concentration and size distribution of ultrafine particles near major highways in Los Angeles. Aerosol Sci Technol 2004, 38:5-13.
56. Zhu Y.F., Kuhn T., Mayo P., Hinds W.C. Comparison of daytime and nighttime concentration profiles and size distributions of ultrafine particles near a major highway. Environ Sci Technol 2006, 40:2531-2536.