A dual-action, low-volume bowel cleanser administered the day before colonoscopy: Results from the SEE CLEAR II study

American Journal of Gastroenterology

Volumn 108, Issue 3, 2013, Pages 401-409

  Katz, Philip O ^a   Rex, Douglas K ^b   Epstein, Michael ^c   Grandhi, Nav K ^d   Vanner, Stephen ^e   Hookey, Lawrence C ^e   Alderfer, Vivian ^f   Joseph, Raymond E ^g  

^a EINSTEIN MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Digestive Disorders Associates   (United States)

^d Greater Cincinnati Gastroenterology Associates   (United States)

^e QUEEN S UNIVERSITY   (Canada)

^f ICON CLINICAL RESEARCH   (United States)

^g Ferring Pharmaceuticals Inc USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISACODYL; MACROGOL; MAGNESIUM CITRATE; PICOSULFATE SODIUM;

ADULT; AGED; ARONCHICK SCALE; ARTICLE; ASCENDING COLON; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COLON LAVAGE; COLONOSCOPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ELECTROCARDIOGRAM; FEMALE; HEADACHE; HUMAN; INTESTINE PREPARATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA AND VOMITING; OTTAWA SCALE; PHASE 3 CLINICAL TRIAL; PHYSICAL EXAMINATION; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; VITAL SIGN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BISACODYL; CATHARTICS; CITRATES; CITRIC ACID; COLON; COLONOSCOPY; FEMALE; HUMANS; MALE; MIDDLE AGED; ORGANOMETALLIC COMPOUNDS; PATIENT SATISFACTION; PICOLINES; POLYETHYLENE GLYCOLS; QUESTIONNAIRES;

EID: 84875229768     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2012.441     Document Type: Article

References (29)

1. Siegel R, Ward E, Brawley O et al. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 2011; 61: 212-36.
2. Rex DK, Johnson DA, Anderson JC et al. American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. Am J Gastroenterol 2009; 104: 739-50.
3. Zauber AG, Winawer SJ, O'Brien MJ et al. Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 2012; 366: 687-96.
4. Swan J, Breen N, Graubard BI et al. Data and trends in cancer screening in the United States: results from the 2005 National Health Interview Survey. Cancer 2010; 116: 4872-81.
5. Centers for Disease Control and Prevention (CDC). Vital signs: colorectal cancer screening among adults aged 50-75 years-United states, 2008. MMWR Morb Mortal Wkly Rep 2010; 59: 808-12.
6. Centers for Disease Control and Prevention (CDC). Cancer screening-United States, 2010. MMWR Morb Mortal Wkly Rep 2012; 61: 41-5.
7. Cohen LB. Split dosing of bowel preparations for colonoscopy: an analysis of its efficacy, safety, and tolerability. Gastrointest Endosc 2010; 72: 406-12.
8. Wexner SD, Beck DE, Baron TH et al. A consensus document on bowel preparation before colonoscopy: prepared by a Task Force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Surg Endosc 2006; 20-1161.
9. Harewood GC, Sharma VK, de Garmo P. Impact of colonoscopy preparation quality on detection of suspected colonic neoplasia. Gastrointest Endosc 2003; 58: 76-9.
10. Froehlich F, Wietlisbach V, Gonvers JJ et al. Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter study. Gastrointest Endosc 2005; 61: 378-84.
11. Di Palma JA, Rodriguez R, McGowan J et al. A randomized clinical study evaluating the safety and efficacy of a new, reduced-volume, oral sulfate colon-cleansing preparation for colonoscopy. Am J Gastroenterol 2009; 104: 2275-84.
12. Lebwohl B, Kastrinos F, Glick M et al. The impact of suboptimal bowel preparation on adenoma miss rates and the factors associated with early repeat colonoscopy. Gastrointest Endosc 2011; 73: 1207-14.
13. Adamcewicz M, Bearelly D, Porat G et al. Mechanism of action and toxicities of purgatives used for colonoscopy preparation. Expert Opin Drug Metab Toxicol 2011; 7: 89-101.
14. Pockros PJ, Foroozan P. Golytely lavage versus a standard colonoscopy preparation. Effect on normal colonic mucosal histology. Gastroenterology 1985; 88: 545-8.
15. Lichtenstein G. Bowel preparations for colonoscopy: a review. Am J Health Syst Pharm 2009; 66: 27-37.
16. Belsey J, Epstein O, Heresbach D. Systematic review: adverse event reports for oral sodium phosphate and polyethylene glycol. Aliment Pharmacol Ther 2009; 29: 15-28.
17. Shawki S, Wexner SD. Oral colorectal cleansing preparations in adults. Drugs 2008; 68: 417-37.
18. Hookey LC, Depew WT, Vanner S. The safety profi le of oral sodium phosphate for colonic cleansing before colonoscopy in adults. Gastrointest Endosc 2002; 56: 895-902.
19. Periodic safety report for Picolax/Picoprep/Picosalax/Pico-Salax/ Cilaxoral. Ferring Pharmaceuticals A/S (Denmark); February 16-2012.
20. Hoy SM, Scott LJ, Wagstaff AJ. Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser. Drugs 2009; 69: 123-36.
21. Hookey LC, Vanner SJ. Pico-salax plus two-day bisacodyl is superior to pico-salax alone or oral sodium phosphate for colon cleansing before colonoscopy. Am J Gastroenterol 2009; 104: 703-9.
22. Parente F, Marino B, Crosta C. Bowel preparation before colonoscopy in the era of mass screening for colo-rectal cancer: a practical approach. Dig Liver Dis 2009; 41: 87-95.
23. Aronchick CA, Lipshutz WH, Wright SH et al. A novel tableted purgative for colonoscopic preparation: efficacy and safety comparisons with Colyte and Fleet Phospho-Soda. Gastrointest Endosc 2000; 52: 346-52.
24. Rostom A, Jolicoeur E. Validation of a new scale for the assessment of bowel preparation quality. Gastrointest Endosc 2004; 59: 482-6.
25. Atreja A, Nepal S, Lashner BA. Making the most of currently available bowel preparations for colonoscopy. Cleve Clin J Med 2010; 77: 317-26.
26. Rex DK, Imperiale TF, Latinovich DR et al. Impact of bowel preparation on effi ciency and cost of colonoscopy. Am J Gastroenterol 2002; 97: 1696-700.
27. Burke CA, Church JM. Enhancing the quality of colonoscopy: the importance of bowel purgatives. Gastrointest Endosc 2007; 66: 565-73.
28. Parra-Blanco A, Nicolas-Perez D, Gimeno-Garcia A et al. The timing of bowel preparation before colonoscopy determines the quality of cleansing, and is a signifi cant factor contributing to the detection of fl at lesions: a randomized study. World J Gastroenterol 2006; 12: 6161-6.
29. Rex DK, Katz P, Bertiger G et al. Split-dose administration of a novel, dual-action, low-volume bowel cleanser for colonoscopy efficacy and safety results from the SEE CLEAR I study. Am J Gastroenterol 2012; 107 (Suppl 1): S746.