Response to lack of specificity of commercial antibodies leads to misidentification of angiotensin type-1 receptor protein

Hypertension

Volumn 61, Issue 4, 2013, Pages

  Herrera, Marcela ^a   Sparks, Matthew A ^a   Alfonso Pecchio, Adolfo R ^b   Harrison Bernard, Lisa M ^c   Coffman, Thomas M ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANTIBODY; HEMAGGLUTININ;

LETTER; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; ANTIBODY SPECIFICITY; IMMUNOHISTOCHEMISTRY; KIDNEY; RECEPTOR, ANGIOTENSIN, TYPE 1;

EID: 84875228331     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.00982     Document Type: Letter

References (4)

1. Elliot KJ, Kimura K, Eguchi S. Lack of specificity of commercial antibodies leads to misidentification of angiotensin type-1 receptor protein. Hypertension. 2013;61-e31.
2. Herrera M, Sparks MA, Alfonso-Pecchio AR, Harrison-Bernard LM, Coffman TM. Lack of specificity of commercial antibodies leads to misidentification of angiotensin type 1 receptor protein. Hypertension. 2013; 61:253-258.
3. Benicky J, Hafko R, Sanchez-Lemus E, Aguilera G, Saavedra JM. Six commercially available angiotensin II AT(1) receptor antibodies are nonspecific. Cell Mol Neurobiol. 2012;32:1353-1365.
4. Rateri DL, Moorleghen JJ, Balakrishnan A, Owens AP III, Howatt DA, Subramanian V, Poduri A, Charnigo R, Cassis LA, Daugherty A. Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice. Circ Res. 2011;108:574-581.