Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 7, 2013, Pages 1898-1904

  Varamini, Pegah ^a   Goh, Wei Huang ^a   Mansfeld, Friederike M ^a   Blanchfield, Joanne T ^a   Wyse, Bruce D ^a   Smith, Maree T ^a   Toth, Istvan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Constipation; Endomorphin 1; Lipoamino acid; Neuropathic pain; Peptide delivery; Respiratory depression

Indexed keywords

ANALGESIC AGENT; ENDOMORPHIN 1; ENDOMORPHIN 1 DERIVATIVE; MORPHINE; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CHEMICAL MODIFICATION; CONSTIPATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG POTENCY; DRUG STRUCTURE; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TOXICITY; HYPERCAPNIA; MALE; NEUROPATHIC PAIN; NONHUMAN; RAT; RESPIRATION DEPRESSION; TREATMENT OUTCOME;

ANALGESICS, OPIOID; ANIMALS; CONSTIPATION; GASTROINTESTINAL MOTILITY; MALE; NEURALGIA; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; RESPIRATION;

RATTUS;

EID: 84875227905     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.01.044     Document Type: Article

References (38)

1. L.A. Lamont, W.J. Tranquilli, and K.A. Grimm Vet Clin. North Am. Small Anim. Pract. 30 2000 703
2. R. Baron B.J. Canning, D. Spina, Sensory Nerves Vol. 194 2009 Springer Berlin, Heidelberg 3
3. Merskey, H.; Bogduk, N.; Pain., I. A. f. t. S. o. Classification of chronic pain: descriptions of chronic pain syndromes and definitions of pain terms; Seattle: IASP Press, 1994.
4. M.T. Smith, and S. South M H. Majewski, Encyclopedia of Life Support Systems 2008 EOLSS Publishers Oxford 1
5. S. Arner, and B.A. Meyerson Pain 33 1988 11
6. R. Przewlocki, and B. Przewlocka Eur. J. Pharmacol. 429 2001 79
7. R.K. Portenoy, and N.A. Hagen Pain 41 1990 273
8. M.A. Czapla, D. Gozal, O.A. Alea, R.C. Beckerman, and J.E. Zadina Am. J. Respir. Crit. Care Med. 162 2000 994
9. A.M. Wilson, R.D. Soignier, J.E. Zadina, A.J. Kastin, W.L. Nores, R.D. Olson, and G.A. Olson Peptides 2000 1871 21
10. R.D. Soignier, A.L. Vaccarino, A.M. Brennan, A.J. Kastin, and J.E. Zadina Life Sci. 67 2000 907
11. L.S. Stone, C.A. Fairbanks, T.M. Laughlin, H.O. Nguyen, T.M. Bushy, M.W. Wessendorf, and G.L. Wilcox NeuroReport 8 1997 3131
12. T.Y. Li, Y. Fujita, Y. Tsuda, A. Miyazaki, A. Ambo, Y. Sasaki, Y. Jinsmaa, S.D. Bryant, L.H. Lazarus, and Y. Okada J. Med. Chem. 48 2005 586
13. Y. Jinsmaa, E. Marczak, Y. Fujita, K. Shiotani, A. Miyazaki, T. Li, Y. Tsuda, A. Ambo, Y. Sasaki, S.D. Bryant, Y. Okada, and L.H. Lazarus Pharmacol. Biochem. Behav. 84 2006 252
14. Y. Koda, M. Del Borgo, S.T. Wessling, L.H. Lazarus, Y. Okada, I. Toth, and J.T. Blanchfield Bioorg. Med. Chem. 16 2008 6286
15. I.E. Goldberg, G.C. Rossi, S.R. Letchworth, J.P. Mathis, J. Ryan-Moro, L. Leventhal, W. Su, D. Emmel, E.A. Bolan, and G.W. Pasternak J. Pharmacol. Exp. Ther. 1007 1998 286
16. C.C. Bihm, C.L. Williams, and T.F. Burks Proc. West. Pharmacol. Soc. 41 1998 81
17. M.A. Czapla, and J.E. Zadina Brain Res. 1059 2005 159
18. P. Varamini, F.M. Mansfeld, J.T. Blanchfield, B.D. Wyse, M.T. Smith, and I. Toth PLoS One 2012 Accepted paper 28th June 2012
19. A. Sugimoto-Watanabe, K. Kubota, K. Fujibayashi, and K. Saito Jpn. J. Pharmacol. 81 1999 264
20. C. Tomboly, A. Peter, and G. Toth Peptides 23 2002 1573
21. G. Horvath Pharmacol. Ther. 88 2000 437
22. R.D. Egleton, T.J. Abbruscato, S.A. Thomas, and T.P. Davis J. Pharm. Sci. 87 1998 1433
23. I. Toth, R.A. Hughes, M.R. Munday, C.A. Murphy, P. Mascagni, and W.A. Gibbons Int. J. Pharm. 68 1991 191
24. Koda, Y. PhD Thesis Thesis, University of Queensland 2007.
25. Leon, S. S., Wu-Pong; Andrew B.C. Yu. Applied biopharmaceutics & pharmacokinetics; New York McGraw-Hill, 2005.
26. P. Varamini, F.M. Mansfeld, J.T. Blanchfield, B.D. Wyse, M.T. Smith, and I. Toth J. Med. Chem. 55 2012 5859
27. C. Emese, J. Gabriella, T. Geza, D. Ildiko, B. Gyorgy, and H. Gyongyi Pain 94 2001 31
28. S.J. Panchal, P. Müller-Schwefe, and J.I. Wurzelmann Int. J. Clin. Pract. 61 2007 1181
29. J.E. Fox-Threlkeld, E.E. Daniel, F. Christinck, V.J. Hruby, S. Cipris, and Z. Woskowska J. Pharmacol. Exp. Ther. 268 1994 689
30. P. Holzer Neurosci. Lett. 361 2004 192
31. Y. Koda, M.T. Liang, J.T. Blanchfield, and I. Toth Int. J. Pharm. 356 2008 37
32. R.H. Dworkin, A.B. O'Connor, M. Backonja, J.T. Farrar, N.B. Finnerup, T.S. Jensen, E.A. Kalso, J.D. Loeser, C. Miaskowski, T.J. Nurmikko, R.K. Portenoy, A.S.C. Rice, B.R. Stacey, R.-D. Treede, D.C. Turk, and M.S. Wallace Pain 132 2007 237
33. B.A. Jordan, and L.A. Devi Nature 399 1999 697
34. J.E. Shook, W.D. Watkins, and E.M. Camporesi Am. Rev. Respir. Dis. 142 1990 895
35. A. Fischer, and B.J. Undem Br. J. Pharmacol. 127 1999 605
36. A. Asakawa, A. Inui, N. Ueno, M. Fujimiya, M.A. Fujino, and M. Kasuga Horm. Metab. Res. 32 2000 51
37. P. Alewood, D. Alewood, L. Miranda, S. Love, W. Meutermans, and D. Wilson Methods Enzymol. 289 1997 14
38. G.J. Bennett, J.M. Chung, M. Honore, and Z. Seltzer Curr. Prot. Neurosci. 2003 Chapter 9, Unit 9