Energy status of pig donor organs after ischemia is independent of donor type

Journal of Surgical Research

Volumn 180, Issue 2, 2013, Pages 356-367

  Stadlbauer, Vanessa ^a   Stiegler, Philipp ^a   Taeubl, Philipp ^a   Sereinigg, Michael ^a   Puntschart, Andreas ^a   Bradatsch, Andrea ^a   Curcic, Pero ^a   Seifert Held, Thomas ^a   Zmugg, Gerda ^a   Stojakovic, Tatjana ^a   Leopold, Barbara ^a   Blattl, Daniela ^a   Horki, Vera ^a   Mayrhauser, Ursula ^a   Wiederstein Grasser, Iris ^a   Leber, Bettina ^a   Jürgens, Günther ^a   Tscheliessnigg, Karlheinz ^a   Hallström, Seth ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Brain dead donor; Heart; High energy phosphates; Kidney; Liver; Living donor; Non heart beating donor; Pancreas

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CELSIOR; CREATINE PHOSPHATE; HYPOXANTHINE; UNIVERSITY OF WISCONSIN SOLUTION; XANTHINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLD ISCHEMIA; CONTROLLED STUDY; EPIDURAL SPACE; EXPERIMENTAL PIG; GENERAL ANESTHESIA; HEART ARREST; HEART DEATH; HEART TRANSPLANTATION; HEART VENTRICLE FIBRILLATION; HIGH ENERGY PHOSPHATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LIVING DONOR; NONHUMAN; ORGAN DONOR; ORGAN TRANSPLANTATION; PANCREAS TRANSPLANTATION; PERFUSION; PRIORITY JOURNAL; RESUSCITATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BRAIN DEATH; ENERGY METABOLISM; ISCHEMIA; KIDNEY; LIVER; LIVING DONORS; MYOCARDIUM; ORGAN TRANSPLANTATION; PANCREAS; SWINE; TISSUE DONORS;

EID: 84875219076     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.05.025     Document Type: Article

References (60)

1. S. Gruttadauria, D. Pagano, G.J. Echeverri, D. Cintorino, M. Spada, and B.G. Gridelli How to face organ shortage in liver transplantation in an area with low rate of deceased donation Updates Surg 62 2010 149
2. G. Stallone, B. Infante, and L. Gesualdo Older donors and older recipients in kidney transplantation J Nephrol 23 Suppl. 15 2010 S98
3. C. Moers, H.G. Leuvenink, and R.J. Ploeg Non-heart beating organ donation: overview and future perspectives Transpl Int 20 2007 567
4. N.R. Brook, J.R. Waller, and M.L. Nicholson Nonheart-beating kidney donation: current practice and future developments Kidney Int 63 2003 1516
5. H. Jeon, and S.G. Lee Living donor liver transplantation Curr Opin Organ Transplant 15 2010 283
6. N.R. Brook, S.A. White, J.R. Waller, P.S. Veitch, and M.L. Nicholson Non-heart beating donor kidneys with delayed graft function have superior graft survival compared with conventional heart-beating donor kidneys that develop delayed graft function Am J Transplant 3 2003 614
7. Y.W. Cho, P.I. Terasaki, J.M. Cecka, and D.W. Gjertson Transplantation of kidneys from donors whose hearts have stopped beating N Engl J Med 338 1998 221
8. S. Feng Donor intervention and organ preservation: where is the science and what are the obstacles? Am J Transplant 10 2010 1155
9. B. Biagioli, S. Scolletta, L. Marchetti, A. Tabucchi, and F. Carlucci Relationships between hemodynamic parameters and myocardial energy and antioxidant status in heart transplantation Biomed Pharmacother 57 2003 156
10. S.C. Stoica High-energy phosphates and the human donor heart J Heart Lung Transplant 23 2004 S244
11. A. Lanir, R.L. Jenkins, C. Caldwell, R.G. Lee, U. Khettry, and M.E. Clouse Hepatic transplantation survival: correlation with adenine nucleotide level in donor liver Hepatology 8 1988 471
12. T. Hirata, T. Fukuse, and T. Nakamura Reperfusion lung injury after cold preservation correlates with decreased levels of intrapulmonary high-energy phosphates Transplantation 69 2000 1793
13. S.W. Ely, and R.M. Berne Protective effects of adenosine in myocardial ischemia Circulation 85 1992 893
14. E.M. Bos, H.G. Leuvenink, H. van Goor, and R.J. Ploeg Kidney grafts from brain dead donors: inferior quality or opportunity for improvement? Kidney Int 72 2007 797
15. A. Barklin Systemic inflammation in the brain-dead organ donor Acta Anaesthesiol Scand 53 2009 425
16. J.A. Van der Hoeven, and R.J. Ploeg Effects of brain death on donor organ viability Curr Opin Organ Transplant 6 2001 75
17. A.L. Brame, and M. Singer Stressing the obvious? An allostatic look at critical illness Crit Care Med 38 2010 S600
18. J. Pratschke, M.J. Wilhelm, and M. Kusaka Brain death and its influence on donor organ quality and outcome after transplantation Transplantation 67 1999 343
19. Y. Futagawa, K. Waki, D.W. Gjertson, and P.I. Terasaki Living-unrelated donors yield higher graft survival rates than parental donors Transplantation 79 2005 1169
20. S.J. Zhang, and T. Wang The influence of brain death on donor liver and the potential mechanisms of protective intervention Front Med 5 2011 8
21. C. Van de Wauwer, A.P. Neyrinck, and N. Geudens The mode of death in the non-heart-beating donor has an impact on lung graft quality Eur J Cardiothorac Surg 36 2009 919
22. Guide for the care and use of laboratory animals 8th ed. 2011 National Academies Press Washington (DC)
23. J. Drenthen, R.A. van Hulst, and J.H. Blok Quantitative EEG monitoring during cerebral air embolism and hyperbaric oxygen treatment in a pig model J Clin Neurophysiol 20 2003 264
24. A. Bacher Management des Organspenders Wiener Klinisches Magazin. Management of Organ Donors 13 2010 36
25. P. Stiegler, M. Sereinigg, and A. Puntschart A 10 min "no-touch" time-is it enough in DCD? A DCD animal study Transplant Int 25 2012 481
26. S. Hallstrom, H. Gasser, and C. Neumayer S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release Circulation 105 2002 3032
27. B. Pelzmann, S. Hallstrom, and P. Schaffer NADH supplementation decreases pinacidil-primed I K ATP in ventricular cardiomyocytes by increasing intracellular ATP Br J Pharmacol 139 2003 749
28. W. Furst, and S. Hallstrom Simultaneous determination of myocardial nucleotides, nucleosides, purine bases and creatine phosphate by ion-pair high-performance liquid chromatography J Chromatogr 578 1992 39
29. H.B. Bittner, E.P. Chen, and C.A. Milano Myocardial beta-adrenergic receptor function and high-energy phosphates in brain death-related cardiac dysfunction Circulation 92 1995 II472
30. R.C. Starling, D.F. Hammer, and P.F. Binkley Adenine nucleotide content in cold preserved human donor hearts and subsequent cardiac performance after orthotopic heart transplantation J Heart Lung Transplant 10 1991 508 [discussion 517]
31. S.C. Stoica, D.K. Satchithananda, and C. Atkinson The energy metabolism in the right and left ventricles of human donor hearts across transplantation Eur J Cardiothorac Surg 23 2003 503
32. W.N. Wicomb, D.K. Cooper, R.P. Lanza, D. Novitzky, and S. Isaacs The effects of brain death and 24 hours' storage by hypothermic perfusion on donor heart function in the pig J Thorac Cardiovasc Surg 91 1986 896
33. M. Galinanes, and D.J. Hearse Brain death-induced impairment of cardiac contractile performance can be reversed by explantation and may not preclude the use of hearts for transplantation Circ Res 71 1992 1213
34. G. Szabo, C. Sebening, and T. Hackert Effects of brain death on myocardial function and ischemic tolerance of potential donor hearts J Heart Lung Transplant 17 1998 921
35. P. Compagnon, H. Wang, and S.L. Lindell Brain death does not affect hepatic allograft function and survival after orthotopic transplantation in a canine model Transplantation 73 2002 1218
36. R. Hickman, C. Rose-Innes, M. Tyler, M. Bracher, Z. Lotz, and J. Fourie Energy charge as an indication of liver viability. A comparison of changes in livers that remained intact with those subjected to autografting Transplantation 53 1992 540
37. D. Manaka, R. Okamoto, and T. Yokoyama Maintenance of liver graft viability in the state of brain death. Synergistic effects of vasopressin and epinephrine on hepatic energy metabolism in brain-dead dogs Transplantation 53 1992 545
38. A. Tanaka, M. Noguchi, and T. Morimoto Influence of hemodilution on hepatic energy metabolism in rat Eur Surg Res 19 1987 200
39. M.M. van den Eijnden, H.G. Leuvenink, and P.J. Ottens Effect of brain death and non-heart-beating kidney donation on renal function and injury: an assessment in the isolated perfused rat kidney Exp Clin Transplant 1 2003 85
40. J.A. van der Hoeven, G. Molema, and G.J. Ter Horst Relationship between duration of brain death and hemodynamic (in)stability on progressive dysfunction and increased immunologic activation of donor kidneys Kidney Int 64 2003 1874
41. S. Hoeger, K. Petrov, and A. Reisenbuechler The additional detrimental effects of cold preservation on transplantation-associated injury in kidneys from living and brain-dead donor rats Transplantation 87 2009 52
42. V. Schmitz, J. Klawitter, and J. Bendrick-Peart Impact of organ preservation using HTK for graft flush and subsequent storage in UW in rat kidney transplantation Eur Surg Res 38 2006 388
43. A. Morita, Y. Kuroda, and Y. Saitoh Evaluation of the viability and energy metabolism of ischemically damaged canine pancreas during preservation by the two-layer (University of Wisconsin solution/perfluorochemical) cold storage method Kobe J Med Sci 38 1992 205
44. R.K. Kharbanda Cardiac conditioning: a review of evolving strategies to reduce ischaemia-reperfusion injury Heart 96 2010 1179
45. F.I. Macedo, and L.E. Miranda Role of ischemic preconditioning in liver transplant: a review of literature Exp Clin Transplant 8 2010 1
46. N. Tapuria, Y. Kumar, M.M. Habib, M. Abu Amara, A.M. Seifalian, and B.R. Davidson Remote ischemic preconditioning: a novel protective method from ischemia reperfusion injury-a review J Surg Res 150 2008 304
47. U. Kunzendorf, B. Hohenstein, and M. Oberbarnscheid Duration of donor brain death and its influence on kidney graft function Am J Transplant 2 2002 292
48. W.N. Nijboer, C. Moers, H.G. Leuvenink, and R.J. Ploeg How important is the duration of the brain death period for the outcome in kidney transplantation? Transpl Int 24 2011 14
49. P. Olinga, J.A. van der Hoeven, M.T. Merema, R.L. Freund, R.J. Ploeg, and G.M. Groothuis The influence of brain death on liver function Liver Int 25 2005 109
50. G.T. Cori, and C.F. Cori Glucose-6-phosphatase of the liver in glycogen storage disease J Biol Chem 199 1952 661
51. J. Baldwin, R.J. Snow, M.J. Gibala, A. Garnham, K. Howarth, and M.A. Febbraio Glycogen availability does not affect the TCA cycle or TAN pools during prolonged, fatiguing exercise J Appl Physiol 94 2003 2181
52. L. Baillet-Blanco, M.C. Beauvieux, H. Gin, V. Rigalleau, and J.L. Gallis Insulin induces a positive relationship between the rates of ATP and glycogen changes in isolated rat liver in presence of glucose; a 31P and 13C NMR study Nutr Metab (Lond) 2 2005 32
53. F. Muhlbacher, F. Langer, and C. Mittermayer Preservation solutions for transplantation Transplant Proc 31 1999 2069
54. T. Minor, and W. Isselhard Synthesis of high energy phosphates during cold ischemic rat liver preservation with gaseous oxygen insufflation Transplantation 61 1996 20
55. B.K. Podesser, and S. Hallstrom Nitric oxide homeostasis as a target for drug additives to cardioplegia Br J Pharmacol 151 2007 930
56. C. Peralta, O. Bulbena, and C. Xaus Ischemic preconditioning: a defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion Transplantation 73 2002 1203
57. C.L. Corps, M. Shires, and D. Crellin Influence on energy kinetics and histology of different preservation solutions seen during cold ischemia in the liver Transplant Proc 41 2009 4088
58. M. Kallerhoff, M. Blech, and F.E. Isemer Metabolic, energetic and structural changes in protected and unprotected kidneys at temperatures of 1 degree C and 25 degrees C Urol Res 16 1988 57
59. R.J. Hene, J. van der Grond, W.H. Boer, W.P. Mali, and H.A. Koomans Pre-transplantation assessment of renal viability with 31P magnetic resonance spectroscopy Kidney Int 46 1994 1694
60. A.J. Christensen, K. Raichle, S.L. Ehlers, and A.J. Bertolatus Effect of family environment and donor source on patient quality of life following renal transplantation Health Psychol 21 2002 468