Determination of steady-state protein breakdown rate in vivo by the disappearance of protein-bound tracer-labeled amino acids: A method applicable in humans

American Journal of Physiology - Endocrinology and Metabolism

Volumn 304, Issue 8, 2013, Pages

  Holm, Lars ^a,b   O'Rourke, Bruce ^b   Ebenstein, David ^b   Toth, Michael J ^c   Bechshoeft, Rasmus ^a   Holstein, Niels Henrik Rathlou ^a   Kjaer, Michael ^a   Matthews, Dwight E ^b,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF VERMONT   (United States)

^c UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Deuterated water; Fractional breakdown rate; Protein degradation; Protein kinetics

Indexed keywords

ALANINE; AMINO ACID; DEUTERIUM OXIDE; GLYCINE; LEUCINE; PHENYLALANINE; PROLINE; SERINE; VALINE;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FRACTIONAL BREAKDOWN RATE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; MASS FRAGMENTOGRAPHY; METABOLIC RATE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RAT; STEADY STATE;

ALANINE; AMINO ACIDS; ANIMALS; BLOOD PROTEINS; BODY WATER; DEUTERIUM OXIDE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; ISOTOPE LABELING; KINETICS; MALE; MODELS, BIOLOGICAL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84875190894     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00579.2012     Document Type: Article

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