ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1

Chemico-Biological Interactions

Volumn 202, Issue 1-3, 2013, Pages 22-31

  Vasiliou, Vasilis ^a   Sandoval, Monica ^a   Backos, Donald S ^a   Jackson, Brian C ^a   Chen, Ying ^a   Reigan, Philip ^a   Lanaspa, Miguel A ^b   Johnson, Richard J ^b   Koppaka, Vindhya ^a   Thompson, David C ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Aldehyde dehydrogenases; ALDH16A1; Gout; HPRT1; Hyperuricemia; Protein protein interactions

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALDH16A1 PROTEIN; CYSTEINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

ALDH16A1 GENE; CATALYSIS; CONFERENCE PAPER; DISEASE ASSOCIATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EVOLUTION; GENE; GENE FUNCTION; GENE STRUCTURE; GOUT; HUMAN; HUMAN CELL; HYPERURICEMIA; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ALDEHYDE DEHYDROGENASE; AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CATALYTIC DOMAIN; CELL LINE; CELL LINE, TUMOR; FISHES; GOUT; HEK293 CELLS; HEP G2 CELLS; HUMANS; HYPERURICEMIA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA SPLICE SITES;

EID: 84875182935     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.12.018     Document Type: Conference Paper

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