Tranexamic acid-induced toxic epidermal necrolysis

Annals of Pharmacotherapy

Volumn 47, Issue 3, 2013, Pages

  Irazabal, Maider Pretel ^a   Martin, Laura Marques ^a   Gil, Leyre Aguado ^a   Gastearena, Miguel Angel Idoate ^a  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; PREDNISONE; TRANEXAMIC ACID;

AGED; ALCOHOL CONSUMPTION; ARTICLE; CASE REPORT; ESOPHAGUS VARICES; FLUID THERAPY; HEMOFILTRATION; HUMAN; HUMAN TISSUE; KIDNEY FAILURE; LIVER CIRRHOSIS; MALE; MULTIPLE ORGAN FAILURE; PRIORITY JOURNAL; RECTUM HEMORRHAGE; RESPIRATORY TRACT INFECTION; TOXIC EPIDERMAL NECROLYSIS; TREATMENT DURATION;

AGED; ANTIFIBRINOLYTIC AGENTS; EPIDERMAL NECROLYSIS, TOXIC; GASTROINTESTINAL HEMORRHAGE; HUMANS; LIVER CIRRHOSIS; MALE; TRANEXAMIC ACID;

EID: 84875171139     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1R637     Document Type: Article

References (12)

1. Pötzsch B, Ivaskevicius V. Haemostasis management of massive bleeding. Hamostaseologie 2011;31:15-20.
2. Dunn CJ, Goa KL. Tranexamic acid: a review of its use in surgery and other indications. Drugs 1999;57:1005-32.
3. Roberts I, Perel P, Prieto-Merino D, et al. Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. BMJ 2012;345:e5839.
4. Lukes AS, Freeman EW, Van Drie D, Baker J, Adomako TL. Safety of tranexamic acid in women with heavy menstrual bleeding: an open-label extension study. Womens Health (Lond Engl) 2011;7:591-8.
5. Lucas-Polomeni MM, Delaval Y, Menestret P, Delaval P, Ecoffey C. A case of anaphylactic shock with tranexamique acid (Exacyl). Ann Fr Anesth Reanim 2004;23:607-9.
6. Imbesi S, Nettis E, Minciullo PL, et al. Hypersensitivity to tranexamic acid: a wide spectrum of adverse reactions. Pharm World Sci 2010;32:416-9.
7. Kavanagh GM, Sansom JE, Harrison P, Warwick JA, Peachey RD. Tranexamic acid (Cyklokapron)-induced fixed-drug eruption. Br J Dermatol 1993;128:229-30.
8. Carrión-Carrión C, del Pozo-Losada J, Gutierrez-Ramos R, et al. Bullous eruption induced by tranexamic acid. Ann Pharmacother 1994;28:1305-6.
9. Tartarone A, Lerose R. Stevens-Johnson syndrome and toxic epidermal necrolysis: what do we know? Ther Drug Monit 2010;32:669-72.
10. Cancer Therapy Evaluation Program. Bethesda, MD: National Cancer Institute. http://ctep.cancer.gov/(accessed 2012 Oct 31).
11. Bastuji-Garin S, Fouchard N, Bertocc M, Roujeau JC, Revuz J, Wolkenstein P. SCORTEN: a severity-of-illness score for toxic epidermal necrolysis. J Invest Dermatol 2000;115:149-53.
12. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.