Marrow-derived mesenchymal stem cells restore biochemical markers of acute liver injury in experimental model

Transplantation Proceedings

Volumn 45, Issue 2, 2013, Pages 480-486

  Gruttadauria, S ^a,b,c   Grosso, G ^c   Pagano, D ^a   Biondi, A ^c   Echeverri, G J ^a   Seria, E ^c   Pietrosi, G ^a   Liotta, R ^a   Basile, F ^c   Gridelli, B ^a,b  

^a MEDITERRANEAN INSTITUTE FOR TRANSPLANTATION AND ADVANCED SPECIALIZED THERAPIES ISMETT   (Italy)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE;

ACUTE LIVER FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; CONTROLLED STUDY; CYTOFLUOROMETRY; LIVER NECROSIS; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE COUNT;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; BONE MARROW TRANSPLANTATION; CARBON TETRACHLORIDE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; FLOW CYTOMETRY; INTERNATIONAL NORMALIZED RATIO; LIVER; LIVER REGENERATION; MESENCHYMAL STEM CELL TRANSPLANTATION; NECROSIS; NEUTROPHIL INFILTRATION; PHENOTYPE; PLATELET COUNT; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84875166740     PISSN: 00411345     EISSN: 18732623     Source Type: Journal    
DOI: 10.1016/j.transproceed.2012.06.087     Document Type: Article

References (15)

1. R. Williams Global challenges in liver disease Hepatology 44 2006 521 526
2. D.C. Zhao, J.X. Lei, R. Chen Bone marrow-derived mesenchymal stem cells protect against experimental liver fibrosis in rats World J Gastroenterol 11 2005 3431 3440
3. H.J. Zimmermann Hepatotoxicity The Adverse Effects of Drugs and Other Chemicals on the Liver 1999 Lippincott Williams & Wilkins Philadelphia, PA
4. B. Ekser, B. Gridelli, A.J. Tector Pig liver xenotransplantation as a bridge to allotransplantation: which patients might benefit? Transplantation 88 2009 1041 1049
5. S.J. Karp Clinical implications of advances in the basic science of liver repair and regeneration Am J Transplant 9 2009 1973 1980
6. I.J. Fox, S.C. Strom To be or not to be: generation of hepatocytes from cells outside the liver Gastroenterology 134 2008 878 881
7. G. Pietrosi, G.B. Vizzini, S. Gruttadauria Clinical applications of hepatocyte transplantation World J Gastroenterol 15 2009 2074 2077
8. B.R. Weil, M.C. Manukyan, J.L. Herrmann The immunomodulatory properties of mesenchymal stem cells: implications for surgical disease J Surg Res 167 2011 78 86
9. M.H. Dahlke, F.C. Popp, F.H. Bahlmann Liver regeneration in a retrorsine/CCl4-induced acute liver failure model: do bone marrow-derived cells contribute? J Hepatol 39 2003 365 373
10. G.K. Michalopoulos, M.C. DeFrances Liver regeneration Science 276 1997 60 66
11. M. Dominici, K. Le Blanc, I. Muller Minimal criteria for defining multipotent mesenchymal stromal cells The International Society for Cellular Therapy position statement Cytotherapy 8 2006 315 317
12. M.H. Dahlke, M. Hoogduijn, E. Eggenhofer Toward MSC in solid organ transplantation: 2008 position paper of the MISOT study group Transplantation 88 2009 614 619
13. F.C. Popp, P. Renner, E. Eggenhofer Mesenchymal stem cells as immunomodulators after liver transplantation Liver Transpl 15 2009 1192 1198
14. Y. Marumoto, S. Terai, Y. Urata Continuous high expression of XBP1 and GRP78 is important for the survival of bone marrow cells in CCl4-treated cirrhotic liver Biochem Biophys Res Commun 367 2008 546 552
15. A.L. Mark, Z. Sun, D.S. Warren Stem cell mobilization is life saving in an animal model of acute liver failure Ann Surg 252 2010 591 596