PD-1 expression on CTL may be related to more severe liver damage in CHB patients with HBV genotype C than in those with genotype B infection

Journal of Viral Hepatitis

Volumn 20, Issue 4, 2013, Pages

  Xibing, G ^a   Xiaojuan, Y ^a   Juanhua, W ^a  

^a Wuxi Hospital for Infectious Diseases   (China)

Author keywords

Chronic hepatitis B; cytotoxic T lymphocyte; Genotype; Hepatitis B virus DNA; Programmed death receptor 1

Indexed keywords

DNA; HEPATITIS B(E) ANTIGEN; HLA A2 ANTIGEN; PROGRAMMED DEATH 1 RECEPTOR;

ANTIGEN EXPRESSION; ARTICLE; COMPARATIVE STUDY; DISEASE SEVERITY; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER FUNCTION; LIVER INJURY; PRIORITY JOURNAL; VIRAL GENETICS;

ALANINE TRANSAMINASE; BILIRUBIN; DNA, VIRAL; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LIVER; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTES, CYTOTOXIC; VIRAL LOAD;

EID: 84875144891     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12009     Document Type: Article

References (2)

1. Bertoletti A, Maini M,. Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection? Curr Opin Microbiol 2000; 3: 387-392.
2. Evans A, Riva A, Cooksley H, et al,. Programmed death 1 expression during antiviral treatment of chronic hepatitis B: impact of hepatitis B e-antigen seroconversion. Hepatology 2008; 48: 759-769.