Statistical simulations to estimate motion-inclusive dose-volume histograms for prediction of rectal morbidity following radiotherapy

Acta Oncologica

Volumn 52, Issue 3, 2013, Pages 666-675

  Thor, Maria ^a,b,c   Apte, Aditya ^c   Deasy, Joseph O ^c   Muren, Ludvig Paul ^a,b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RADIOTHERAPY; DOSE VOLUME HISTOGRAM; FOLLOW UP; HISTOGRAM; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MOTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROSTATE CANCER; RADIATION DOSE; TREATMENT PLANNING; CANCER PATIENT; COMPUTER ASSISTED RADIOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; INTENSITY MODULATED RADIATION THERAPY; ORGANS AT RISK; PELVIS LYMPH NODE; QUANTITATIVE ANALYSIS; RADIATION DOSE DISTRIBUTION; RADIATION INJURY; RECTAL TOXICITY; SEMINAL VESICLE; SIMULATION; STATISTICAL ANALYSIS;

COHORT STUDIES; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FOLLOW-UP STUDIES; HUMANS; MALE; MORBIDITY; MOTION; MOVEMENT; ORGANS AT RISK; PROGNOSIS; PROSTATE; PROSTATIC NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RECTAL DISEASES; RECTUM; STATISTICS AS TOPIC; TUMOR BURDEN;

EID: 84875137241     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2012.720382     Document Type: Article

References (42)

1. MS, v an Herk M, Y an D, B oersma LJ, Koper PCM, Lebesque JV. A model to simulate day-to-day variations in rectum shape . Int J Radiat Oncol Biol Phys 2002; 54 : 615-25 (Pubitemid 35286832)
2. van Haaren PM, B el A. H ofman P, v an Vulpen M, K otte AN, van der Heide UA . Infl uence of daily setup measurements and corrections on the estimated delivered dose during IMRT treatment of prostate cancer patients . Radiother Oncol 2009; 90 : 291-8
3. Kvinnsland Y, M uren LP. The impact of organ motion on intestine doses and complication probabilities in radiotherapy of bladder cancer . Radiother Oncol 2005; 76 : 43-7 (Pubitemid 41096513)
4. van Zijtveld M, Dirkx M, Breuers M, Kuipers R, Heijmen B . Evaluation of the ' dose of the day ' for IMRT prostate cancer patients derived from portal dose measurements and conebeam CT . Radiother Oncol 2010; 96 : 172-7
5. Chen L, P askalev K, X u X, Z hu J, W ang L, P rice R A, et a l . Rectal dose variation during the course of image-guided radiation therapy of prostate cancer . Radiother Oncol 2010; 95 : 198-202
6. McKenzie A, v an Herk M, M ijnheer B. M argins for geometric uncertainty around organs at risk in radiotherapy . Radiother Oncol 2002; 62 : 299-307 (Pubitemid 34304193)
7. van Herk M. E rrors and margins in radiotherapy. S emin Radiat Oncol 2004; 14 : 52-64 (Pubitemid 38168954)
8. Yan D, J affray D A, W ong J W. A model to accumulate fractionated dose in a deforming organ . Int J Radiat Oncol Biol Phys 1999; 44 : 665-75 (Pubitemid 29258443)
9. Thor M, P etersen JB, B entzen L, H ø y er M, M uren LP . Deformable image registration for contour propagation from CT to cone-beam CT scans in radiotherapy of prostate cancer . Acta Oncol 2011; 50 : 918-25
10. Korreman S, R asch C, M cNair H, V erellen D, O elfke U, Maingon P, et al . The European Society of Therapeutic Radiology and Oncology-European Institute of Radiotherapy (ESTRO-EIR) report on 3D CT-based in-room image guidance systems: A practical and technical review and guide . Radiother Oncol 2010; 94 : 129-44
11. Fontenla E, P elizzari C A, R oeske J C, C hen G T. U sing serial imaging data to model variabilities in organ position and shape during radiotherapy . Phys Med Biol 2001; 46 : 2317-36 (Pubitemid 32895530)
12. Kvinnsland Y., Muren L P, D ahl O. A Monte Carlo study of the impact of the choice of rectum volume defi nition on estimates of equivalent uniform doses and the volume parameter . Phys Med Biol 2004; 49 : 3341-52 (Pubitemid 39161947)
13. Kvinnsland Y, M uren LP, D ahl O. E valuation of a new method for calculation of cumulative doses in the rectum wall using repeat CT scans . Acta Oncol 2004; 43 : 388-95 (Pubitemid 38887860)
14. Muren L P, K arlsdottir A, K vinnsland Y, W enzel-Larsen T, Dahl O . Testing the new ICRU 62 ' Planning Organ at Risk Volume ' concept for the rectum . Radiother Oncol 2005; 75 : 293-302 (Pubitemid 41007974)
15. Thor M, V æt h M, Karlsdottir A, M uren LP . Rectum motion and morbidity prediction: Improving correlation between late morbidity and DVH parameters through use of rectum planning organ at risk volumes . Acta Oncol 2010; 49 : 1061-8
16. ICRU Report 62. Prescribing, recording and reporting photon beam radiotherapy (supplement to ICRU Report 50). Bethesda, MD: International Commission on Radiation Units and Measurements; 1999
17. Hysing L B, K vinnsland Y, L ord H, M uren L P. P lanning organ at risk volume margins for organ motion of the intestine . Radiother Oncol 2006; 80 : 349-54 (Pubitemid 44397206)
18. Muren LP, E kerold R, K vinnsland Y, K arlsdottir A, D ahl O . On the use of margins for geometrical uncertainties around the rectum in radiotherapy planning . Radiother Oncol 2004; 70 : 11-9 (Pubitemid 38177157)
19. Deasy JO. C ERR: A computational environment for radiotherapy research . Med Phys 2003; 30 : 979-85 (Pubitemid 36578702)
20. Karlsdottir A, M uren L P, W enzel-Larsen T, D ahl O. Late gastrointestinal morbidity after three-dimensional conformal radiation therapy for prostate cancer fades with time in contrast to genitourinary morbidity . Int J Radiat Oncol Biol Phys 2008; 70 : 1478-86 (Pubitemid 351417770)
21. Cox JD, S tetz J, P ajak TF. T oxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) . Int J Radiat Oncol Biol Phys 1995; 5 : 1341-6
22. Muren LP, W asbø E, H elle SI, H ysing LB, K arlsdottir A, Odland OH, et al . Intensity-modulated radiotherapy of pelvic lymph nodes in locally advanced prostate cancer: Planning procedures and early experiences . Int J Radiat Oncol Biol Phys 2008; 71 : 1034-41
23. Moman MR, v an der Heide UA, K otte A N, v an Moorselaar RJ, Bol GH, Franken SP, et al . Long-term experience with transrectal and transperineal implantations of fi ducial gold markers in the prostate for position verifi cation in external beam radiotherapy; feasibility, toxicity and quality of life . Radiother Oncol 2010; 96 : 38-42
24. Thö r nqvist S, Bentzen L, Petersen JBB, Hysing LB, Muren LP . Plan robustness of simultaneous integrated boost radiotherapy of prostate and lymph nodes for different image-guidance and delivery techniques . Acta Oncol 2011; 50 : 926-34
25. El Naqa I, S uneja G, L indsay PE, H ope A J, A laly JR, Vicic M, et al . Dose response explorer: An integrated opensource tool for exploring and modelling radiotherapy dosevolume outcome relationships . Phys Med Biol 2006; 51 : 5719-35 (Pubitemid 46217664)
26. Lehmann E L. R ank tests for comparing two treatments: The treatment of ties. In: Lehmann EL, editor. Nonparametrics, statistical methods based on ranks, 1st ed. New York: Springer Science - Business Media; 2006. pp 18-22
27. Engels B, Tournel K, Soete G, Storme G. A ssessment of rectal distention in radiotherapy of prostate cancer using daily megavoltage CT image guidance . Radiother Oncol 2009; 90 : 377-81
28. Fellin G, F iorino C, R ancati T, V avassori V, B accolini M, Bianchi C, et al . Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: Results of a large multicenter observational study . Radiother Oncol 2009; 93 : 197-202
29. Gulliford S L, P artridge M, S ydes M R, A ndreyev J, Dearnaley DP. A comparison of dose-volume constraints derived using peak and longitudinal defi nitions of late rectal toxicity . Radiother Oncol 2010; 94 : 241-7
30. Jackson A, S kwarchuk MW Zelefsky MJ, C owen DM, Venkatraman ES, Levegrun S, et al . Late rectal bleeding after conformal radiotherapy of prostate cancer (II): Volume effects and dose-volume histograms . Int J Radiat Oncol Biol Phys 2001; 49 : 685-98 (Pubitemid 32112195)
31. Fiorino C, Valdagni R, Rancati T, Sanguineti G . Dose-volume effects for normal tissues in external radiotherapy: Pelvis . Radiother Oncol 2009; 93 : 153-67
32. Sripadam R, S tanford J, H enry A M, J ackson A, M oore CJ, Price P . Rectal motion can reduce CTV coverage and increase rectal dose during prostate radiotherapy: A daily cone-beam CT study . Radiother Oncol 2009; 90 : 312-7
33. Hatton JA, G reer PB, T ang C, W right P, C app A, G upta S, et al . Does the planning dose-volume histogram represent treatment doses in image-guided prostate radiation therapy? Assessment with cone-beam computerised tomography scans . Radiother Oncol 2011; 98 : 162-8
34. Anderson NS, Y u JB, P eschel RE, D ecker RH. A signifi cant decrease in rectal volume and diameter during prostate IMRT . Radiother Oncol 2011; 98 : 187-91
35. Jiang R, B arnett R B, C how J C, C hen J Z. The use of spatial dose gradients and probability density function to evaluate the effect of internal organ motion for prostate IMRT treatment planning . Phys Med Biol 2007; 52 : 1469-84 (Pubitemid 46646398)
36. Mavroidis P, A xelsson S, H y öd ynmaa S, R ajala J, P itkä nen MA, Lind BK, et al . Effects of positioning uncertainty and breathing on dose delivery and radiation pneumonitis prediction in breast cancer . Acta Oncol 2002; 41 : 471-85 (Pubitemid 35222047)
37. S öh n M, B irkner M, Y an D, A lber M. M odelling individual geometric variation based on dominant eigenmodes of organ deformation: Implementation and evaluation . Phys Med Biol 2005; 50 : 5893-908 (Pubitemid 41795840)
38. Budiarto E, K eijzer M, S torchi P R, H oogeman M S, Bondar L, Mutanga TF, et al . A population-based model to describe geometrical uncertainties in radiotherapy: Applied to prostate cases . Phys Med Biol 2011; 56 : 1045-61
39. Yan D, V icini F, W ong J, M artinez A. A daptive radiation therapy . Phys Med Biol 1997; 42 : 123-32 (Pubitemid 27055957)
40. Th ör nqvist S, P etersen J BB, H ø y er M, B entzen LN, Muren LP . Propagation of target and organ at risk contours in radiotherapy of prostate cancer using deformable image registration . Acta Oncol 2010; 49 : 1023-32
41. Liu M, M oiseenko V, A granovich A, K arvat A, K wan W, Saleh ZH, et al . Normal Tissue Complication Probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: A test of the QUANTEC-recommended NTCP model . Acta Oncol 2010; 49 : 1040-4
42. Maeda Y, H ø yer M, Lundby L, Buntzen S, Laurberg S . Temporary sacral nerve stimulation for faecal incontinence following pelvic radiotherapy . Radiother Oncol 2010; 97 : 108-12