A computerized integrated system for the assessment of central and peripheral chemoreflex sensitivity

Computer Methods and Programs in Biomedicine

Volumn 110, Issue 1, 2013, Pages 58-65

  Maestri, Roberto ^a   Bruschi, Claudio ^a   Pinna, Gian Domenico ^a  

^a IRCCS   (Italy)

Author keywords

Central chemoreflex; Chemoreflex sensitivity; Peripheral chemoreflex

Indexed keywords

CENTRAL CHEMOREFLEX; CHEMOREFLEX SENSITIVITY; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; COMPREHENSIVE ASSESSMENT; INTERACTIVE CONTROL; OUTLIERS REJECTIONS; PERIPHERAL CHEMOREFLEX; RESPIRATORY FUNCTION;

CARBON DIOXIDE; PULMONARY DISEASES; QUALITY ASSURANCE;

MATLAB;

CARBON DIOXIDE;

ARTICLE; BREATH ANALYSIS; CHEMORECEPTOR REFLEX; CIRCULATION TIME; COMPUTER PROGRAM; COMPUTER SYSTEM; HUMAN; LUNG VOLUME; OXYGEN SATURATION; RESPIRATORY FUNCTION;

ADAPTATION, PHYSIOLOGICAL; ANOXIA; BREATH TESTS; CHEMORECEPTOR CELLS; COMPUTER SYSTEMS; DIAGNOSIS, COMPUTER-ASSISTED; HUMANS; REFLEX; RESPIRATORY PHYSIOLOGICAL PROCESSES; SOFTWARE;

EID: 84875116756     PISSN: 01692607     EISSN: 18727565     Source Type: Journal    
DOI: 10.1016/j.cmpb.2012.09.007     Document Type: Article

References (20)

1. León-Velarde F., Richalet J.P. Respiratory control in residents at high altitude: physiology and pathophysiology. High Altitude Medicine & Biology 2006, 7(2):125-137.
2. 2 in high-altitude natives and patients with chronic mountain sickness. Journal of Applied Physiology 2003, 94(3):1279-1287.
3. Ciarka A., Cuylits N., Vachiery J.L., Lamotte M., Degaute J.P., Naeije R., van de Borne P. Increased peripheral chemoreceptors sensitivity and exercise ventilation in heart transplant recipients. Circulation 2006, 113(2):252-257.
4. Janssen C., Beloka S., Kayembe P., Deboeck G., Adamopoulos D., Naeije R., van de Borne P. Decreased ventilatory response to exercise by dopamine-induced inhibition of peripheral chemosensitivity. Respiratory Physiology & Neurobiology 2009, 168(3):250-253.
5. Wang D., Grunstein R.R., Teichtahl H. Association between ventilatory response to hypercapnia and obstructive sleep apnea-hypopnea index in asymptomatic subjects. Sleep & Breathing 2007, 11(2):103-108.
6. Solin P., Roebuck T., Johns D.P., Walters E.H., Naughton M.T. Peripheral and central ventilatory responses in central sleep apnea with and without congestive heart failure. American Journal of Respiratory and Critical Care Medicine 2000, 162(6):2194-2200.
7. Ponikowski P., Chua T.P., Anker S.D., Francis D.P., Doehner W., Banasiak W., Poole-Wilson P.A., Piepoli M.F., Coats A.J. Peripheral chemoreceptor hypersensitivity: an ominous sign in patients with chronic heart failure. Circulation 2001, 104(5):544-549.
8. Giannoni A., Emdin M., Bramanti F., Iudice G., Francis D.P., Barsotti A., Piepoli M., Passino C. Combined increased chemosensitivity to hypoxia and hypercapnia as a prognosticator in heart failure. Journal of the American College of Cardiology 2009, 53(21):1975-1980.
9. Read D.J. A clinical method for assessing the ventilatory response to carbon dioxide. Australasian Annals of Medicine 1967, 16(1):20-32.
10. Chua T.P., Ponikowski P., Harrington D., Chambers J., Coats A.J. Contribution of peripheral chemoreceptors to ventilation and the effects of their suppression on exercise tolerance in chronic heart failure. Heart 1996, 76(6):483-489.
11. 2 as a clinical test of the peripheral chemoreflex. Journal of Applied Physiology 1988, 64(1):84-89.
12. Edelman N.H., Epstein P.E., Lahiri S., Cherniack N.S. Ventilatory responses to transient hypoxia and hypercapnia in man. Respiration Physiology 1973, 17(3):302-314.
13. Chua T.P., Ponikowski P., Webb-Peploe K., Harrington D., Anker S.D., Piepoli M., Coats A.J. Clinical characteristics of chronic heart failure patients with an augmented peripheral chemoreflex. European Heart Journal 1997, 18:480-486.
14. Ponikowski P., Anker S.D., Chua T.P., Francis D., Banasiak W., Poole-Wilson P.A., Coats A.J., Piepoli M. Oscillatory breathing patterns during wakefulness in patients with chronic heart failure. Clinical implications and role of augmented peripheral chemosensitivity. Circulation 1999, 100:2418-2424.
15. Cherniack N.S., Longobardo G.S. Mathematical models of periodic breathing and their usefulness in understanding cardiovascular and respiratory disorders. Experimental Physiology 2006, 64(1):295-305.
16. Milic-Emili J., Grunstein M.M. Drive and timing components of ventilation. Chest 1976, 70(1 Suppl.):131-133.
17. Tukey J.W. Exploratory Data Analysis 1977, Addison-Wesley, Reading, MA.
18. Wilcox R.R. Fundamentals of Modern Statistical Methods 2001, Springer-Verlag, New York, pp. 33-36 (Chapter 3).
19. Huber P.J. Robust Statistics 1981, John Wiley & Sons, New York.
20. 2 by rebreathing. Chest 1976, 70:118-121.