Boron enhances strength and alters mineral composition of bone in rabbits fed a high energy diet

Journal of Trace Elements in Medicine and Biology

Volumn 27, Issue 2, 2013, Pages 148-153

  Hakki, Sema S ^a   Dundar, Niyazi ^a   Kayis, Seyit Ali ^a   Hakki, Erdogan E ^a   Hamurcu, Mehmet ^a   Kerimoglu, Ulku ^a   Baspinar, Nuri ^a   Basoglu, Abdullah ^a   Nielsen, Forrest H ^b  

^a SELCUK UNIVERSITY   (Turkey)

^b UNIVERSITY OF NORTH DAKOTA   (United States)

Author keywords

Bone composition; Bone strength; Boron; Minerals; Obesity

Indexed keywords

BORON; CALCIUM; MAGNESIUM; PHOSPHORUS;

ALFALFA; ANIMAL EXPERIMENT; ANIMAL FOOD; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DENSITY; BONE MASS; BONE MINERAL; BONE STRENGTH; CONTROLLED STUDY; DIET; DISCRIMINANT ANALYSIS; FEMALE; FEMUR; FEMUR CONDYLE; HIGH CALORIC DIET; NONHUMAN; OBESITY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RABBIT; TIBIA;

ANIMALS; BONE AND BONES; BONE DENSITY; BORON; DIET; ENERGY INTAKE; FEEDING BEHAVIOR; FEMALE; FEMUR; MINERALS; PRINCIPAL COMPONENT ANALYSIS; RABBITS; TIBIA;

MEDICAGO SATIVA; ORYCTOLAGUS CUNICULUS;

EID: 84875097363     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2012.07.001     Document Type: Article

References (36)

1. 3 nutriture on indices of energy substrate utilization and mineral metabolism in the chick. J Bone Miner Res 1994, 9:171-181.
2. Fort D.J., Rogers R.L., McLaughlin D.W., Sellers C.M., Schlekat C.M. Impact of boron deficiency on Xenopus laevis. A summary of biological effects and potential biochemical roles. Biol Trace Elem Res 2002, 90:117-142.
3. Nielsen F.H., Stoecker B.J. Boron and fish oil have different beneficial effects on strength and trabecular microarchitecture of bone. J Trace Elem Med Biol 2009, 23:195-203.
4. Gorustovich A.A., Steimetz T., Nielsen F.H., Guglielmotti M.B. Histomorphometric study of alveolar bone healing in rats fed a boron-deficient diet. Anat Rec 2008, 291:441-447.
5. Gorustovich A.A., Steimetz T., Nielsen F.H., Guglielmotti M.B. A histomorphometric study of alveolar bone modeling and remodeling in mice fed a boron-deficient diet. Arch Oral Biol 2008, 53:677-682.
6. Uysal T., Ustdal A., Sonmez M.F., Ozturk F. Stimulation of bone formation by dietary boron in an orthopedically expanded suture in rabbits. Angle Orthod 2009, 79:984-990.
7. Durand L.A.H., Mesones R.V., Nielsen F.H., Gorustovich A.A. Histomorphometric and microchemical characterization of maturing dental enamel in rats fed a boron-deficient diet. Biol Trace Elem Res 2010, 135:242-252.
8. Armstrong T.A., Spears J.W., Crenshaw T.D., Nielsen F.H. Boron supplementation of a semipurified diet for weanling pigs improves feed efficiency and bone strength characteristics and alter plasma lipid metabolites. J Nutr 2000, 139:2575-2581.
9. Armstrong T.A., Flowers W.L., Spears J.W., Nielsen F.H. Long-term effects of boron supplementation on reproductive characteristics and bone mechanical properties in gilts. J Anim Sci 2002, 80:154-161.
10. Naghii M.R., Torkaman G., Mofid M. Effects of boron and calcium supplementation on mechanical properties of bone in rats. Biofactors 2006, 28:195-201.
11. Rossi A.F., Miles R.D., Damron B.L., Flunker L.K. Effects of dietary boron supplementation on broilers. Poult Sci 1993, 72:2124-2130.
12. Wilson J.H., Ruszler P.L. Effects of boron on growing pullets. Biol Trace Elem Res 1997, 56:287-294.
13. Wilson J.H., Ruszler P.L. Long term effects of boron on layer bone strength and production parameters. Brit Poult Sci 1998, 39:11-15.
14. Rico H., Crespo E., Hernández E.R., Seco C., Crespo R. Influence of boron supplementation on vertebral and femoral bone mass in rats on strenuous treadmill exercise. A morphometric, densitometric, and histomorphometric study. J Clin Densitom 2002, 5:187-192.
15. Hakki S.S., Bozkurt B.S., Hakki E. Boron regulates mineralized tissue-associated proteins in osteoblasts (MC3T3-E1). J Trace Elem Med Biol 2010, 24:243-250.
16. Ying X., Cheng S., Wang W., Lin Z., Chen Q., Zhang W., Kou D., Shen Y., Cheng X., Rompis F.A., Peng L., Zhu Lu C. Effect of boron on osteogenic differentiation of human bone marrow stromal cells. Biol Trace Elem Res. 2011, 144:306-315.
17. Nielsen F.H. Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in raats. J Trace Elem Med Biol 2009, 23:204-213.
18. 2+-initiated oxidations. Free Rad Biol Med 2004, 36:1303-1316.
19. Zhang R., Ma J., Xia M., Zhu H., Ling W.-H. Mild hyperhomocysteinemia induced by feeding rats diets rich in methionine or deficient in folate promotes early atherosclerotic inflammatory processes. J Nutr 2004, 134:825-830.
20. Clowes J.A., Riggs B.L., Khosla S. The role of the immune system in the pathophysiology of osteoporosis. Imunnol Rev 2005, 208:207-227.
21. Blum M., Harris S.S., Must A., Naumova E.N., Phillips S.M., Rand W.M., Dawson-Hughes B. Leptin, body composition and bone mineral density in premenopausal women. Calcif Tissue Int 2003, 73:27-32.
22. Pollock N.K., Laing E.M., Baile C.A., Hamrick M.W., Hall D.B., Lewis R.D. Is adiposity advantageous for bone strength? A peripheral quantitative computed tomography study in late adolescent females. Am J Clin Nutr 2007, 86:1530-1538.
23. Basoglu A., Baspinar N., Ozturk A.S., Akalin P.P. Effects of boron administration on hepatic steatosis, hematological and biochemical profiles in obese rabbits. Trace Elem Electrolytes 2010, 27:225-231.
24. Payne R.W., Murray D.A., Harding S.A., Baird D.B., Soutar D.M. GenStat for Windows. Introduction 2003, VSN International, Hemel Hempstead. 7th ed.
25. Nielsen F.H., Meacham S.L. Growing evidence for human health benefits of boron. Evid Based Complement Altern Med 2011, DOI: 10.1177/2156587211407638.
26. National Research Council, National Academies of Science Boron. Mineral tolerance of animals 2005, National Academic Press, Washington, DC, pp. 60-71. 2nd ed.
27. Reid I.R. Relationships between fat and bone. Osteoporos Int 2008, 19:595-606.
28. Albala C., Yanez M., Devoto E., Sostin C., Zeballos L., Santos J.L. Obesity as a protective factor for postmenopausal osteoporosis. Int J Obes 1996, 20:1027-1032.
29. De Laet C., Kanis J.A., Oden A., Johanson H., Johnell O., Delmas P., Eisman J.A., Kroger H., Fujiwara S., Garnero P., McCloskey E.V., Mellstrom D., Melton L.J., Meunier P.J., Pols H.A., Reeve J., Silman A., Tenenhouse A. Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos Int 2005, 16:1330-1338.
30. Robling A.G., Castillo A.B., Turner C.H. Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng 2006, 8:455-498.
31. Nielsen F.H., Shuler T.R. Studies of the interaction between boron and calcium, and its modification by magnesium and potassium, in rats. Biol Trace Elem Res 1992, 35:225-237.
32. Nielsen F.H. Magnesium, inflammation, and obesity in chronic disease. Nutr Rev 2010, 68:333-340.
33. Nielsen F.H. Dietary fat composition modifies the effect of boron on bone characteristics and plasma lipids in rats. BioFactors 2004, 20:161-171.
34. Rude R.K., Singer F.R., Gruber H.E. Skeletal and hormonal effects of magnesium deficiency. J Am Coll Nutr 2009, 28:131-141.
35. Cousins R.J. Zinc. Present knowledge in nutrition 2006, vol. 1:445-457. ILSI Press, Washington DC. 9th ed.
36. Yamaguchi M. Role of zinc in bone metabolism and preventive effect on bone disorder. Biomed Res Trace Elem 2007, 18:346-366.