Toxicity hazard of organophosphate insecticide malathion identified by in vitro methods

Neuroendocrinology Letters

Volumn 33, Issue SUPPL. 3, 2012, Pages 53-59

  Jira, David ^a   Janousek, Stanislav ^b   Pikula, Jiri ^a   Vitula, Frantisek ^a   Kejlova, Kristina ^b  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^b NATIONAL INSTITUTE OF PUBLIC HEALTH   (Czech Republic)

Author keywords

Cytotoxicity; Embryotoxicity; Genotoxicity; In vitro methods; Malathion

Indexed keywords

MALATHION;

AMNION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CHICK EMBRYO; CHORIOALLANTOIS; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYO MORTALITY; EMBRYOTOXICITY; ERYTHROID CELL; EYE IRRITATION; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; LD 50; MICRONUCLEUS TEST; NONHUMAN; RISK ASSESSMENT; SKIN IRRITATION; SURVIVAL;

EID: 84875080027     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Aktar MW, Sengupta D, Chowdhury A (2009). Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol 2(1): 1-12.
2. Bakr RFA, Ramadan RH, 2 El-Sawy S, Hussien SMA (2012) Ultrastructure of the Midgut of theThird Larval Instar of Chrysomya megacephala (Diptera:Calliphoridae) fed on malathion treated diet. Egypt Acad J Biolog Sci 3 (1): 13-26.
3. Blasiak J, Jaloszynski P, Trzeciak A, Szyfter K (1999) In vitro studies on the genotoxicity of the organophosphorus insecticide malathion and its two analogues. Mutat Res 445(2): 275-283. (Pubitemid 29518336)
4. Brouwer A, Longnecker MP, Birnbaum LS, Cogliano J, Kostyniak P, Moore J, Schantz S, Winneke G (1999). Characterization of potential endocrine related health effects at low dose levels of exposure to PCBs. Environ Health Perspect 107: 639-649. (Pubitemid 29423559)
5. Clothier R, Dierickx P, Lakhanisky T, Fabre M, Betanzos M, Curren R, Sjöström M, Raabe H, Bourne N, Hernandez V, Mainez J, Owen M, Watts S, Anthonissen R (2008). A Database of IC50 Values and Principal Component Analysis of Results from Six Basal Cytotoxicity Assays, for Use in the Modelling of the In Vivo and In Vitro Data of the EU ACuteTox Project. ATLA 36: 503-519.
6. EC (2006). Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission.
7. EC (2008). Council Regulation (EC) No 440/2008 of 30 May 2008 laying down test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Official Journal L 142, 31/05/2008: 0001-0739.
8. Fortunato JJ, Feier G, Vitali AM, Petronilho FC, Dal-Pizzol F, Quevedo J (2006). Malathion-induced oxidative stress in rat brain regions. Neurochem Res 31(5): 671-678. (Pubitemid 43886415)
9. Ginter PM, Capper SA, Swayne LE (2002). Public Health Leadership and Management: Cases and Context. Sage Publications Inc., Thousand Oaks, California.
10. ICCVAM/NTP/NICEATM (2006). ICCVAM Test Method Evaluation Report (TMER): In Vitro Cytotoxicity Test Methods for Estimating Starting Doses for Acute Oral Systemic Toxicity Testing, NIH Publication No. 07-4519. Research Triangle Park, NC, USA: National Institute of Environmental Health Sciences. Available at http://iccvam.niehs.nih.gov/docs/acutetox-docs/BRD-TMER/TMERappxC-Nov200 6.pdf (accessed 9.8.2012)
11. John S, Kale M, Rathore N, Bhatnager D (2001). Protective effect of vitamin E in dimethioate and malathion induced oxidative stress in rat erythrocytes. J Nutr Biochem 12 (9): 500-504. (Pubitemid 32785651)
12. Kamrin M A (1997). Pesticide Profiles: Toxicity, Environmental Impact, and Fate. Lewis Publishers, New York: 191-195.
13. Montgomery MP, Kamel F, Saldana TM, Alavanja MC, Sandler DP (2008). Incident diabetes and pesticide exposure among licensed pesticide applicators. Agricultural Health Study, 1993-2003. Am J Epidemio. 167(10): 1235-46. (Pubitemid 351670637)
14. Moore PD, Yedjou CG, Tchounwou PB (2010). Malathion-induced oxidative stress, cytotoxicity, and genotoxicity in human liver carcinoma (HepG2) cells. Environ Toxicol 25(3): 221-6.
15. Muniz JF, McCauley L, Scherer J, Lasarev M, Koshy M, Kow YW, Nazar-Stewart V, Kisby GE (2008). Biomarkers of oxidative stress and DNA damage in agricultural workers: a pilot study. Toxicol Appl Pharmacol 227(1): 97-107.
16. OECD (2010) Guidance Document No 129 on using Cytotoxicity Tests to Estimate Starting Doses for Acute Oral Systemic Toxicity Tests. Paris, France (http://www.oecd.org. Available at: http://iccvam.niehs.nih.gov/SuppDocs/FedDocs/OECD/OECD-GD129.pdf
17. OMARI YI. (2009). Cytogenetic study on workmen occupationally exposed to pesticides. BJMG 12(1): 51-59.
18. OMARI YI. (2011). Micronucleus analysis and mitotic index in a Jordanian population exposed to pesticides of organophosphate: malathion and chlorpyrifos. CARYOLOGIA 64 (2): 173-178.
19. Pourmirza AA (2000). Toxic effects of malathion and endosulfan on chick embryo. J Agric Sci Tech 2: 161-166.
20. Reus GZ, Valvassori SS, Nuernberg H, Comim CM, Stringari RB, Padilha PT, Leffa DD, Tavares P, Dagostim G, Paula MM, Andrade VM, Quevedo J (2008). DNA damage after acute and chronic treatment with malathion in rats. J Agric Food Chem 56(16): 7560-7565.
21. Rezga R, Mornaguia B, Benahmedb M, Chouchanec SG, Belhajhmidab N, Abdeladhimb M, Kamouna A, El-fazaaa S, Gharbi N (2010). Malathion exposure modulates hypothalamic gene expression and induces dyslipedemia in Wistar rats. Food Chemical Toxicol 48 (6): 1473-1477.
22. Robertson JL, Preisler HK (1992). Pesticide Bioassays with Arthropods. CRC Press, London: 129.
23. Santi A, Menezes Ch, F.Duarte MM, Leitemperger J, lopez T, Loro VI (2011). Oxidative stress biomarkers and acetylcholinesterase activity in human erythrocytes exposed to clomazone (in vitro). Interdiscip Toxicol 4(3): 149-153.
24. Talcott RE, Mallipudi NM, Fukuto TR (1979). Malathion carboxylesterase titer and its relationship to malathion toxicity. Toxicol Appl Pharmacol 50 (30): 501-504. (Pubitemid 10193915)
25. Wolf T, Luepke NP (1997). Formation of micronuclei in incubated hen's eggs as a measure of genotoxicity. Mutat Res 394: 163-75.
26. Wolf T, Niehaus-Rolf C, Luepke NP (2002). Some new methodological aspects of the hen's egg test for micronucleus induction (HET-MN). Mutat Res 514: 59-76. (Pubitemid 34114080)
27. Wolf T, Niehaus-Rolf C, Banduhn N, Eschrich D, Scheel J, Luepke NP (2008). The hen's egg test for micronucleus induction (HET-MN): Novel analyses with a series of well-characterized substances support the further evaluation of the test system. Mut Res/Gen Toxicol Environ Mutagen 650 (2): 150-164.