Glycogen synthesis is a required component of the nitrogen stress response in Synechococcus elongatus PCC 7942

Algal Research

Volumn 2, Issue 2, 2013, Pages 98-106

  Hickman, Jason W ^a   Kotovic, Kimberly M ^a   Miller, Cameron ^a   Warrener, Paul ^a   Kaiser, Brett ^a   Jurista, Tracey ^a   Budde, Mark ^a   Cross, Fred ^b   Roberts, James M ^c   Carleton, Michael ^a  

^a Matrix Genetics   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

Author keywords

2 oxoglutarate; Cyanobacteria; Glycogen; NblA; Nitrogen stress

Indexed keywords

CYANOBACTERIA; SYNECHOCOCCUS ELONGATUS; SYNECHOCOCCUS ELONGATUS PCC 7942;

EID: 84875059350     PISSN: 22119264     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.algal.2013.01.008     Document Type: Article

References (38)

1. Dubinsky Z., Berman-Frank I. Uncoupling primary production from population growth in photosynthesizing organisms in aquatic ecosystems. Aquatic Science 2001, 63:4-17.
2. Schwarz R., Forchhammer K. Acclimation of unicellular cyanobacteria to macronutrient deficiency: emergence of a complex network of cellular responses. Microbiology 2005, 151:2503-2514.
3. Herrero A., Muro-Pastor A.M., Flores E. Nitrogen control in cyanobacteria. Journal of Bacteriology 2001, 183:411-425.
4. Ohashi Y., Shi W., Takatani N., Aichi M., Maeda S., Watanabe S., Yoshikawa H., Omata T. Regulation of nitrate assimilation in cyanobacteria. Journal of Experimental Botany 2011, 62:1411-1424.
5. Schwarz R., Grossman A.R. A response regulator of cyanobacteria integrates diverse environmental signals and is critical for survival under extreme conditions. Proceedings of the National Academy of Sciences of the United States of America 1998, 95:11008-11013.
6. Aichi M., Omata T. Involvement of NtcB, a LysR family transcription factor, in nitrite activation of the nitrate assimilation operon in the cyanobacterium Synechococcus sp. strain PCC 7942. Journal of Bacteriology 1997, 179:4671-4675.
7. Luque I., Forchhammer K. Nitrogen assimilation and C/N balance sensing. The Cyanobacteria Molecular Biology, Genomics and Evolution 2008, 335-382. Caister Academic Press, Norfolk, UK. A. Herrero, E. Flores (Eds.).
8. Collier J.L., Grossman A.R. A small polypeptide triggers complete degradation of light-harvesting phycobiliproteins in nutrient-deprived cyanobacteria. EMBO Journal 1994, 13:1039-1047.
9. Luque I., Zabulon G., Contreras A., Houmard J. Convergence of two global transcriptional regulators on nitrogen induction of the stress-acclimation gene nblA in the cyanobacterium Synechococcus sp. PCC 7942. Molecular Microbiology 2001, 41:937-947.
10. Kato H., Kubo T., Hayashi M., Kobayashi I., Yagasaki T., Chibazakura T., Watanaba S., Yoshikawa H. Interactions between histidine kinase NblS and the response regulators RpaB and SrrA are involved in the bleaching process of the cyanobacterium Synechococcus elongatus PCC 7942. Plant & Cell Physiology 2011, 52:2115-2122.
11. Kato H., Chibazakura T., Yoshikawa H. NblR is a novel one-component response regulator in the cyanobacterium Synechococcus elongatus PCC 7942. Bioscience, Biotechnology, and Biochemistry 2008, 72:1072-1079.
12. Ruiz D., Salinas P., Lopez-Redondo M.L., Cayuela M.L., Marina A., Contreras A. Phosphorylation-independent activation of the atypical response regulator NblR. Microbiology 2008, 154:3002-3015.
13. Espinosa J., Lopez-Redondo M.L., Miguel-Romero L., Neira J.L., Marina A., Contreras A. Insights into the mechanism of activation of the phosphorylation-independent response regulator NblR. Role of residues Cys69 and Cys96. Biochimica et Biophysica Acta 2012, 1819:382-390.
14. Muro-Pastor M.I., Reyes J.C., Florencio F.J. Cyanobacteria perceive nitrogen status by sensing intracellular 2-oxoglutarate levels. Journal of Biological Chemistry 2001, 276:38320-38328.
15. Tanigawa R., Shirokane M., Si S.Maeda, Omata T., Tanaka K., Takahashi H. Transcriptional activation of NtcA-dependent promoters of Synechococcus sp. PCC 7942 by 2-oxoglutarate in vitro. Proceedings of the National Academy of Sciences of the United States of America 2002, 99:4251-4255.
16. Llacer J.L., Espinosa J., Castells M.A., Contreras A., Forchhammer K., Rubio V. Structural basis for the regulation of NtcA-dependent transcription by proteins PipX and PII. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:15397-15402.
17. Espinosa J., Forchhammer K., Burillo S., Contreras A. Interaction network in cyanobacterial nitrogen regulation: PipX, a protein that interacts in a 2-oxoglutarate dependent manner with PII and NtcA. Molecular Microbiology 2006, 61:457-469.
18. Allen N.M. Cyanobacterial cell inclusions. Annual Review of Microbiology 1984, 38:1-25.
19. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: a Laboratory Manual 1989, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Clerico E.M., Ditty J.L., Golden S.S. Specialized techniques for site-directed mutagenesis in cyanobacteria. Methods in Molecular Biology 2007, 362:155-171.
21. Suzuki E., Ohkawa H., Moriya K., Matsubara T., Nagaike Y., Fujiwara S., Tsuzuki M., Nakamura Y. Carbohydrate metabolism in mutants of the cyanobacterium Synechococcus elongatus PCC 7942 defective in glycogen synthesis. Applied and Environmental Microbiology 2010, 76:3153-3159.
22. Senior P.J. Regulation of nitrogen metabolism in Escherichia coli and Klebsiella aerogenes: studies with the continuous-culture technique. Journal of Bacteriology 1975, 123:407-418.
23. Evans A.M., DeHaven C.D., Barrett T., Mitchell M., Milgram E. Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. Analytical Chemistry 2009, 81:6656-6667.
24. Sha W., da Costa K.A., Fischer L.M., Milburn M.V., Lawton K.A., Berger A., Jia W., Zeisel S.H. Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. The FASEB Journal 2010, 24:2962-2975.
25. Boudonck K.J., Mitchell M.W., Német L., Keresztes L., Nyska A., Shinar D., Rosenstock M. Discovery of metabolomics biomarkers for early detection of nephrotoxicity. Toxicologic Pathology 2009, 37:280-292.
26. Dehaven C.D., Evans A.M., Dai H., Lawton K.A. Organization of GC/MS and LC/MS metabolomics data into chemical libraries. Journal of Cheminformatics 2010, 2:9.
27. DeRuyter Y.S., Fromme P. Molecular structure of the photosynthetic apparatus. The Cyanobacteria Molecular Biology, Genomics and Evolution 2008, 217-269. Caister Academic Press, Norfolk, UK. A. Herrero, E. Flores (Eds.).
28. Vazquez-Bermudez M.F., Herrero A., Flores E. 2-Oxoglutarate increases the binding affinity of the NtcA (nitrogen control) transcription factor for the Synechococcus glnA promoter. FEBS Letters 2002, 512:71-74.
29. Vazquez-Bermudez M.F., Herrero A., Flores E. Uptake of 2-oxoglutarate in Synechococcus strains transformed with the Escherichia coli kgtP gene. Journal of Bacteriology 2000, 182:211-215.
30. Sauer J., Gorl M., Forchhammer K. Nitrogen starvation in Synechococcus PCC 7942: involvement of glutamine synthetase and NtcA in phycobiliprotein degradation and survival. Archives of Microbiology 1999, 172:247-255.
31. Zlotnik I., Dubinsky Z. The effect of light and temperature on DOC excretion by phytoplankton. Limnology and Oceanography 1989, 34:831-839.
32. Bertillson S., Berglund O., Pullin M.J., Chisholm S.W. Release of dissolved organic matter by prochlorococcus. Vie et Milieu 2005, 55:225-231.
33. Elmorjani K., Herdman M. Metabolic control of phycocyanin degradation in the cyanobacteroium Synechocystis PCC 6803: a glucose effect. Journal of General Microbiology 1987, 133:1685-1694.
34. Seol W., Shatkin A.J. Escherichia coli alpha-ketoglutarate permease is a constitutively expressed proton symporter. Journal of Biological Chemistry 1992, 267:6409-6413.
35. Karradt A., Sobanski J., Mattow J., Lockau W., Baier K. NblA, a key protein of phycobilisome degradation, interacts with ClpC, a HSP100 chaperone partner of a cyanobacterial Clp protease. Journal of Biological Chemistry 2008, 283:32394-32403.
36. Funayama S., Gancedo J.M., Gancedo C. Turnover of yeast fructose-bisphosphatase in different metabolic conditions. European Journal of Biochemistry 1980, 109:61-66.
37. Carrieri D., Paddock T., Maness P., Seibert M., Yu J. Photo-catalytic conversion of carbon dioxide to organic acids by a recombinant cyanobacterium incapable of glycogen storage. Energy & Environmental Science 2012, 5:9457-9461.
38. Gründel M., Scheunemann R., Lockau W., Zilliges Y. Impaired glycogen synthesis causes metabolic overflow and affects stress responses in the cyanobacterium Synechocystis sp. PCC 6803. Microbiology 2012, 158:3032-3043.