-
1
-
-
0036182417
-
Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
-
Shimokawa H. Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases. J Cardiovasc Pharmacol. 2002;39:319-327.
-
(2002)
J Cardiovasc Pharmacol.
, vol.39
, pp. 319-327
-
-
Shimokawa, H.1
-
2
-
-
0037223388
-
Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with coronary microvascular spasm
-
Mohri M, Shimokawa H, Hirakawa Y, Masumoto A, Takeshita A. Rho-kinase inhibition with intracoronary fasudil prevents myocardial ischemia in patients with coronary microvascular spasm. J Am Coll Cardiol. 2003;41:15-19.
-
(2003)
J Am Coll Cardiol.
, vol.41
, pp. 15-19
-
-
Mohri, M.1
Shimokawa, H.2
Hirakawa, Y.3
Masumoto, A.4
Takeshita, A.5
-
3
-
-
33646763902
-
Rho kinases in cardiovascular physiology and pathophysiology
-
Loirand G, Guerin P, Pacaud P. Rho kinases in cardiovascular physiology and pathophysiology. Circ Res. 2006;98:322-324.
-
(2006)
Circ Res.
, vol.98
, pp. 322-324
-
-
Loirand, G.1
Guerin, P.2
Pacaud, P.3
-
5
-
-
0035316139
-
Involvement of Rhokinase in hypertensive vascular disease: A novel therapeutic target in hypertension
-
Mukai Y, Shimokawa H, Matoba T, et al. Involvement of Rhokinase in hypertensive vascular disease: a novel therapeutic target in hypertension. FASEB J. 2001;15:1062-1064.
-
(2001)
FASEB J.
, vol.15
, pp. 1062-1064
-
-
Mukai, Y.1
Shimokawa, H.2
Matoba, T.3
-
6
-
-
14244260105
-
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
-
Fukumoto Y, Matoba T, Ito A, et al. Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension. Heart. 2005;91:391-392.
-
(2005)
Heart.
, vol.91
, pp. 391-392
-
-
Fukumoto, Y.1
Matoba, T.2
Ito, A.3
-
7
-
-
33749538874
-
The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
-
Ying H, Biroc S, Li W-W, et al. The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models. Mol Cancer Ther. 2006;5:2158-2164.
-
(2006)
Mol Cancer Ther.
, vol.5
, pp. 2158-2164
-
-
Ying, H.1
Biroc, S.2
Li, W.-W.3
-
8
-
-
0034708373
-
Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells
-
Somlyo AV, Bradshaw D, Ramos S, Murphy C, Myers CE, Somlyo AP. Rho-kinase inhibitor retards migration and in vivo dissemination of human prostate cancer cells. Biochem Biophys Res Comm. 2000;269:652-659.
-
(2000)
Biochem Biophys Res Comm.
, vol.269
, pp. 652-659
-
-
Somlyo, A.V.1
Bradshaw, D.2
Ramos, S.3
Murphy, C.4
Myers, C.E.5
Somlyo, A.P.6
-
9
-
-
18944372230
-
Rho-kinase, a promising drug target for neurological disorders
-
Mueller B, Mack H, Teusch N. Rho-kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov. 2005; 4:387-398.
-
(2005)
Nat Rev Drug Discov.
, vol.4
, pp. 387-398
-
-
Mueller, B.1
Mack, H.2
Teusch, N.3
-
10
-
-
79952230532
-
Effects of fasudil, a rhoassociated protein kinase inhibitor, on optic nerve head blood flow in rabbits
-
Sugiyama T, Shibata M, Kajiura S, et al. Effects of fasudil, a rhoassociated protein kinase inhibitor, on optic nerve head blood flow in rabbits. Invest Ophthalmol Vis Sci. 2011;52:64-69.
-
(2011)
Invest Ophthalmol Vis Sci.
, vol.52
, pp. 64-69
-
-
Sugiyama, T.1
Shibata, M.2
Kajiura, S.3
-
11
-
-
34249694646
-
Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
-
Rao V, Epstein D. Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. Biodrugs. 2007;11:167-177.
-
(2007)
Biodrugs.
, vol.11
, pp. 167-177
-
-
Rao, V.1
Epstein, D.2
-
12
-
-
0035726683
-
Reduction of intraocular pressure by topical administration of an inhibitor of the Rhoassociated protein kinase
-
Waki M, Yoshida Y, Oka T, Azuma M. Reduction of intraocular pressure by topical administration of an inhibitor of the Rhoassociated protein kinase. Curr Eye Res. 2001;22:470-474.
-
(2001)
Curr Eye Res.
, vol.22
, pp. 470-474
-
-
Waki, M.1
Yoshida, Y.2
Oka, T.3
Azuma, M.4
-
13
-
-
0035164065
-
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo M, Tanihara H, Inatani M, et al. Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci. 2001;42:137-44.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
-
14
-
-
34548073671
-
Effects of topical administration of Y-39983, a selective rho-associated protein kinase inhibitor, on ocular tissues in rabbits in monkeys
-
Tokushige H, Inatani M, Nemoto S, et al. Effects of topical administration of Y-39983, a selective rho-associated protein kinase inhibitor, on ocular tissues in rabbits in monkeys. Invest Ophthalmol Vis Sci. 2007;48:3216-3222.
-
(2007)
Invest Ophthalmol Vis Sci.
, vol.48
, pp. 3216-3222
-
-
Tokushige, H.1
Inatani, M.2
Nemoto, S.3
-
15
-
-
80054998108
-
Ocular hypotensive effect of the rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension
-
Williams RD, Novack GD, Van Haarlem T, Kopczynski C. Ocular hypotensive effect of the rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension. Am J Ophthalmol. 2011;152:834-841.
-
(2011)
Am J Ophthalmol.
, vol.152
, pp. 834-841
-
-
Williams, R.D.1
Novack, G.D.2
van Haarlem, T.3
Kopczynski, C.4
-
16
-
-
0035164065
-
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo M, Tanihara H, Inatani M, et al. Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci. 2001;42:137-144.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
-
17
-
-
79958807531
-
Novel ocular antihypertensive compounds in clinical trials
-
Chen J, Runyan S, Robinson M. Novel ocular antihypertensive compounds in clinical trials. Clin Ophthalmol. 2011;5:667-677.
-
(2011)
Clin Ophthalmol.
, vol.5
, pp. 667-677
-
-
Chen, J.1
Runyan, S.2
Robinson, M.3
-
18
-
-
39149130336
-
The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes
-
Lu Z, Overgy DR, Scott PA, Freddo TF, Gong H. The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes. Exp Eye Res. 2008; 86:271-281.
-
(2008)
Exp Eye Res.
, vol.86
, pp. 271-281
-
-
Lu, Z.1
Overgy, D.R.2
Scott, P.A.3
Freddo, T.F.4
Gong, H.5
-
19
-
-
0035066006
-
Modulation of aqueous humor outflow facility by the rho kinase-specific inhibitor Y-27632
-
Rao PV, Deng P-F, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the rho kinase-specific inhibitor Y-27632. Invest Ophthalmol Vis Sci. 2001;42:1029-1037.
-
(2001)
Invest Ophthalmol Vis Sci.
, vol.42
, pp. 1029-1037
-
-
Rao, P.V.1
Deng, P.-F.2
Kumar, J.3
Epstein, D.L.4
-
20
-
-
24144445945
-
Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow
-
Rao PV, Deng P, Maddala R, Epstein D, Shimokawa H. Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow. Mol Vis. 2005;11:288-297.
-
(2005)
Mol Vis.
, vol.11
, pp. 288-297
-
-
Rao, P.V.1
Deng, P.2
Maddala, R.3
Epstein, D.4
Shimokawa, H.5
-
21
-
-
0032559362
-
Rho GTPases and actin cytoskeleton
-
Hall A. Rho GTPases and actin cytoskeleton. Science. 1998; 279:509-514.
-
(1998)
Science.
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
22
-
-
0029995797
-
Rho-stimulated contractility drives the formation of actin stress fibers and focal adhesions
-
Chrzanowska-Wodnicka M, Burridge K. Rho-stimulated contractility drives the formation of actin stress fibers and focal adhesions. J Cell Biol. 1996;133:1403-1415.
-
(1996)
J Cell Biol.
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
23
-
-
0032860424
-
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
-
Kaibuchi K, Kuroda S, Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu Rev Biochem. 1999;68:459-486.
-
(1999)
Annu Rev Biochem.
, vol.68
, pp. 459-486
-
-
Kaibuchi, K.1
Kuroda, S.2
Amano, M.3
|