The residues and environmental risks of multiple veterinary antibiotics in animal faeces

Environmental Monitoring and Assessment

Volumn 185, Issue 3, 2013, Pages 2211-2220

  Li, Yan Xia ^a   Zhang, Xue Lian ^a   Li, Wei ^b   Lu, Xiao Fei ^a   Liu, Bei ^a   Wang, Jing ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b NANJING INSTITUTE OF ENVIRONMENTAL SCIENCES   (China)

Author keywords

Animal faeces; Ecological risk; Risk evaluations; Veterinary antibiotics

Indexed keywords

CONCENTRATED ANIMAL FEEDING OPERATIONS; ECOLOGICAL RISKS; ENVIRONMENTAL RISKS; FLUOROQUINOLONES; HAZARD QUOTIENTS; OXYTETRACYCLINES (OTC); RISK EVALUATION; VETERINARY ANTIBIOTIC;

ANTIBIOTICS; ECOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MANURES; SULFUR COMPOUNDS;

ANIMALS;

ANTIBIOTIC AGENT; CHLORTETRACYCLINE; CIPROFLOXACIN; DIFLOXACIN; ENROFLOXACIN; NORFLOXACIN; OXYTETRACYCLINE; SULFACHLORPYRIDAZINE; SULFAGUANIDINE; SULFAMERAZINE; SULFAMETHOXAZOLE; SULFAMONOMETHOXINE; SULFANILAMIDE; SULFONAMIDE; TETRACYCLINE; TYLOSIN; VETERINARY DRUG; ANTIINFECTIVE AGENT;

ANTIBIOTICS; CONCENTRATION (COMPOSITION); ENVIRONMENTAL ASSESSMENT; ENVIRONMENTAL RISK; FECES; HAZARD ASSESSMENT; MANURE; RISK ASSESSMENT;

ANALYTIC METHOD; ARTICLE; CHICKEN; CHINA; CONCENTRATION (PARAMETERS); COW; DAIRYING; ENVIRONMENT; FECES; HAZARD RATIO; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; RISK ASSESSMENT; SWINE; ANIMAL; CATTLE; CHEMISTRY; ENVIRONMENTAL MONITORING; MANURE; POLLUTANT;

CHINA;

ANIMALIA; SUIDAE;

ANIMALS; ANTI-BACTERIAL AGENTS; CATTLE; CHICKENS; CHINA; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; FECES; MANURE; RISK ASSESSMENT; SWINE; VETERINARY DRUGS;

MLCS; MLOWN;

EID: 84874988753     PISSN: 01676369     EISSN: 15732959     Source Type: Journal    
DOI: 10.1007/s10661-012-2702-1     Document Type: Article

References (46)

1. A.H.I., Animal Health Institute (2002). Available from: http://www.ahi.org. Accessed 25 May 2008.
2. Arikan, O.A., Mulbry, W., & Rice C. (2009). Management of antibiotic residues from agricultural sources: Use of composting to reduce chlortetracycline residues in beef manure from treated animals. Journal of Hazardous Materials, 164(2-3), 483-489
3. Arikan, O. A., Sikora, L. J., Mulbry, W., Khan, S. U., & Foster, G. D. (2007). Composting rapidly reduces levels of extractable oxytetracycline in manure from therapeutically treated beef calves. Bioresource Technology, 98(1), 169-176.
4. Boxall, A. B. A., Kolpin, D. W., Halling-Sørensen, B., & Tolls, J. (2003). Are veterinary medicines causing environmental risks? Environmental Science & Technology, 37(15), 286A-294A.
5. Campagnolo, E. R., Johnson, K. R., Karpati, A., Rubin, C. S., Kolpin, D. W., Meyer, M. T., et al. (2002). Antimicrobial residues in animal waste and water resources proximal to large-scale swine and poultry feeding operations. Science of the Total Environment, 299(1-3), 89-95.
6. Chen, H., Dong, Y. H., Wang, H., An, Q., Zhang, J. Q., & Liu, X. C. (2008). Residual characteristics of sulfanilamide in animal feces in Jiangsu Province. Journal of Agro-Environment Science, 27(1), 0385-0389 (in Chinese).
7. Commission of European Communities. (1992). Commission directive 92/18/EEC of 20 March 1992 modifying the Annex to Council Directive 81/852/EEC on the approximation of the laws of Member States relating to analytical, pharmacotoxicological and clinical standards and protocols in respect of the testing of veterinary medical products. Official Journal of the European Communities, L97, 1.
8. Department of Rural Surveys, National Bureau of Statistics. (2007). China agricultural statistic year book. Beijing: China Statistics Press.
9. Department of Rural Surveys, National Bureau of Statistics. (2009). China agricultural statistic year book. Beijing: China Statistics Press.
10. Dolliver, H., Gupta, S., & Noll, S. (2008). Antibiotic degradation during manure composting. Jounal of Environmental Quality, 37, 1245-1253.
11. European Agency for the Evaluation of Medicinal Products (EMEA). (2006). Guideline on environmental impact assessment for veterinary medicinal products. In support of the VICH guidelines GL6 and GL38, 38-39.
12. Ferrari, B., Paxeus, N., Giudice, R. L., Pollio, A., & Garric, J. (2003). Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofbric acid, and diclofenac. Ecotoxicology and Environmental Safety, 55(3), 359-370.
13. Halling-Sørensen, B. (2000). Algal toxicity of antibacterial agents used in intensive farming. Chemosphere, 40(7), 731-739.
14. Halling-Sørensen, B., Nielsen, S. N., Lanzky, P. F., Ingerslev, F., Holten Lützhøft, H. C., & Jørgense, S. E. (1998). Occurrence, fate and effects of pharmaceutical substances in the environment - a review. Chemosphere, 36(2), 357-393.
15. Hamscher, G., Sczesny, S., Höper, H., & Nau, H. (2002). Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Analytical Chemistry, 74(7), 1509-1518.
16. Heuer, H., Solehati, Q., Zimmerling, U., Kleineidam, K., Schloter, M., Müller, T., et al. (2011). Accumulation of sulfonamide resistance genes in arable soils due to repeated application of manure containing sulfadiazine. Applied and Environmental Microbiology, 77, 2527-2530.
17. Hu, X. G., Luo, Y., Zhou, Q. X., & Xu, L. (2008). Determination of thirteen antibiotics residues in manure by solid phase extraction and high performance liquid chromatography. Chinese Journal of Analytical Chemistry, 36(9), 1162-1166 (in Chinese).
18. Hu, X. G., Zhou, Q. X., & Luo, Y. (2010). Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, northern China. Environmental Pollution, 158(9), 2992-2998.
19. Jacobsen, A. M., & Halling-Sørensen, B. (2006). Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 384(5), 1164-1174.
20. KarcI, A., & BalcIoǧlu, I. A. (2009). Investigation of the tetracycline, sulfonamide, and fluoroquinolone antimicrobial compounds in animal manure and agricultural soils in Turkey. Science of the Total Environment, 407(16), 4652-4664.
21. Kemper, N. (2008). Veterinary antibiotics in the aquatic and terrestrial environment. Ecological Indicators, 8, 1-13.
22. Kim, K. R., Owens, G., Kwon, S. I., So, K. H., Lee, D. B., & Ok, Y. S. (2011). Occurrence and environmental fate of veterinary antibiotics in the terrestrial environment. Water Air & Soil Pollution, 214(1-4), 163-174.
23. Kleineidam, K., Sharma, S., Kotzerke, A., Heuer, H., Thiele-Bruhn, S., Smalla, K., et al. (2010). Effect of sulfadiazine on abundance and diversity of denitrifying bacteria by determining nirK and nirS genes in two arable soils. Microbial Ecology, 60(4), 703-707.
24. Kong, W. D., Zhu, Y. G., Fu, B. J., Marschner, P., & He, J. Z. (2006). The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community. Environmental Pollution, 143(1), 129-137.
25. Kulshrestha, A., Giese, R. F., & Aga, D. S. (2004). Investigating the molecular interactions of oxytetracycline in clay and organic matter: insights on factors affecting its mobility in soil. Environmental Science & Technology, 38(15), 4097-4105.
26. Kumar, K., Gupta, S. C., Chander, Y., & Singh, A. K. (2005). Antibiotic use in agriculture and their impact on the terrestrial environment. Advances in Agronomy, 87, 1-54.
27. Li, W., Li, Y. X., Zhang, F. S., Lin, C. Y., Xiong, X., & Zhang, Z. (2007). The spatial and temporal distribution features of animal production in three Northeast Provinces and the impacts of manure nutrients on the local environment. Journal of Agro-Environment Science, 26(6), 2350-2357 (in Chinese).
28. Luo, Y., Xu, L., Rysz, M., Wang, Y. Q., Zhang, H., & Alvarez, P. J. J. (2011). Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environmental Science & Technology, 45(5), 1827-1833.
29. Martínez-Carballo, E., González-Barreiro, C., Scharf, S., & Gans, O. (2007). Environmental monitoring study of selected veterinary antibiotics in animal manure and soils in Austria. Environmental Pollution, 148(2), 570-579.
30. McEwen, S. A., & Fedorka-Cray, P. J. (2002). Antimicrobial use and resistance in animals. Clinical Infectious Diseases, 34(supplement 3), S93-S106.
31. Mellon, M., Benbrook, C., & Benbrook, K. L. (2001) Hogging it!: estimates of antimicrobial abuse in livestock. Union of concerned scientists, UCS Publications, Cambridge, MA, USA. Available from: http://www.ucsusa.org/ publications/food-and-environment/antibiotics-and-food/hogging-it-estimates-of- antimicrobial-abuse-in-livestock.html. Accessed 4 June 2012.
32. Motoyama, M., Nakagawa, S., Tanoue, R., Sato, Y., Nomiyama, K., & Shinohara, R. (2011). Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. Chemosphere, 84(4), 432-438.
33. Pan, X., Qiang, Z. M., Ben, W. W., & Chen, M. X. (2011). Residual veterinary antibiotics in swine manure from concentrated animal feeding operations in Shandong Province, China. Chemosphere, 84(5), 695-700.
34. Park, S., & Choi, K. (2008). Hazard assessment of commonly used agricultural antibiotics on aquatic ecosystems. Ecotoxicology, 17(6), 526-538.
35. Pils, R. V., & Lairo, D. A. (2007). Sorption of tetracycline and chlortetracycline on K-and Ca-saturated soil clays, humic substances, and clay-humic complexes. Environmental Science & Technology, 41(6), 1928-1933.
36. Rong, X. Y., & Liang, Y. (2008). Examples analysis of validation of analytical methods for testing the non-residual solvents impurities by HPLC. China Licensed Pharmacist, 5(11), 36-40 (in Chinese).
37. Sarmah, A. K., Meyer, M. T., & Boxall, A. B. A. (2006). A global perspective on the use, sales, exposure pathways, ocurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere, 65(5), 725-759.
38. Spaepen, K. R. I., Van Leemput, L. J. J., Wislocki, P. G., & Verschueren, C. (1997). A uniform procedure to estimate the predicted environmental concentration of the residues of veterinary medicines in soil. Environmental Toxicology and Chemistry, 16(9), 1977-1982.
39. Thiele-Bruhn, S., & Beck, I. C. (2005). Effects of sulfonamide and tetracycline antibiotics on soil microbial activity and microbial biomass. Chemosphere, 59(4), 457-465.
40. Vaclavik, E., Halling-Sørensen, B., & Ingerslev, F. (2004). Evaluation of manometric respiration tests to assess the effects of veterinary antibiotics in soil. Chemosphere, 56(7), 667-676.
41. Watanabe, N., Bergamaschi, B. A., Loftin, K. A., Meyer, M. T., & Harter, T. (2010). Use and environmental occurrence of antibiotics in freestall dairy farms with manured forage fields. Environmental Science & Technology, 44(17), 6591-6600.
42. Winckler, C., & Grafe, A. (2000). Abschatzung des stoffeintrags in Böden durch tierarzneimittel und pharmakologisch wirksame futterzusatzstoffe. UBA-Texte 44/00, Berlin.
43. Winckler, C., Engels, H., & Hund-Rinke, K. (2003). Verhalten von tetracyclinen und anderen veterinärantibiotika in wirtschaftsdünger und Boden. UFOPLAN, 200 73 248 Berlin.
44. Xu, W. H., Zhang, G., Li, X. D., Zou, S. C., Li, P., Hu, Z. H., et al. (2007). Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China. Water Research, 41(19), 4526-4534.
45. Zhang, H. M., Zhang, M. K., & Gu, G. P. (2008). Residues of tetracyclines in livestock and poultry manures and agricultural soils from North Zhejiang Province. Journal of Ecology and Rural Environment, 24(3), 69-73 (in Chinese).
46. Zhao, L., Dong, Y. H., & Wang, H. (2010). Residues of veterinary antibiotics in manure from feedlot livestocks in eight provinces of China. Science of The Total Environment, 408(5), 1069-1075.