Intra-arterial chemotherapy is more effective than sequential periocular and intravenous chemotherapy as salvage treatment for relapsed retinoblastoma

Pediatric Blood and Cancer

Volumn 60, Issue 5, 2013, Pages 766-770

  Schaiquevich, Paula ^a   Ceciliano, Alejandro ^b   Millan, Natalia ^a   Taich, Paula ^a   Villasante, Francisco ^b   Fandino, Adriana C ^a   Dominguez, Julieta ^a   Chantada, Guillermo L ^a  

^a HOSPITAL DE PEDIATRÍA PROF DR JUAN P GARRAHAN   (Argentina)

^b Clinica y Maternidad Suizo Argentina   (Argentina)

Author keywords

Intra arterial chemotherapy; Retinoblastoma; Topotecan

Indexed keywords

CARBOPLATIN; CYCLOPHOSPHAMIDE; MELPHALAN; STEROID; TOPOTECAN;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER INVASION; CANCER LOCALIZATION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; DRUG EFFICACY; DRUG FEVER; EDEMA; ENUCLEATION; EVENT FREE SURVIVAL; EXTERNAL BEAM RADIOTHERAPY; FEVER; HUMAN; MONOTHERAPY; MULTIPLE CYCLE TREATMENT; NEUROLOGICAL COMPLICATION; NEUTROPENIA; OPTIC NERVE DISEASE; OPTIC NERVE EDEMA; ORBIT EDEMA; PRESCHOOL CHILD; PRIORITY JOURNAL; RECURRENT CANCER; RETINA VASCULITIS; RETINOBLASTOMA; RETROSPECTIVE STUDY; SEPSIS; SURVIVAL TIME; SYSTEMIC DISEASE; THROMBOSIS; URINARY TRACT INFECTION;

ADMINISTRATION, INTRAVENOUS; ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ETOPOSIDE; FEMALE; HUMANS; INJECTIONS, INTRA-ARTERIAL; INJECTIONS, INTRAOCULAR; MALE; MELPHALAN; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; OPHTHALMIC ARTERY; RETINAL NEOPLASMS; RETINOBLASTOMA; RETROSPECTIVE STUDIES; SALVAGE THERAPY; TOPOTECAN; TREATMENT OUTCOME; VINCRISTINE; YOUNG ADULT;

EID: 84874971861     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.24356     Document Type: Article

References (30)

1. Chan MP, Hungerford JL, Kingston JE, et al. Salvage external beam radiotherapy after failed primary chemotherapy for bilateral retinoblastoma: Rate of eye and vision preservation. Br J Ophthalmol 2009; 93: 891-894.
2. Abramson DH, Ellsworth RM, Rosenblatt M, et al. Retreatment of retinoblastoma with external beam irradiation. Arch Ophthalmol 1982; 100: 1257-1260.
3. Gombos DS, Cauchi PA, Hungerford JL, et al. Vitreous relapse following primary chemotherapy for retinoblastoma: Is adjuvant diode laser a risk factor? Br J Ophthalmol 2006; 90: 1168-1172.
4. Dunkel IJ, Chantada GL, Fandino AC, et al. Lack of activity of oral etoposide for relapsed intraocular retinoblastoma. Ophthalmic Genet 2004; 25: 25-29.
5. Chantada GL, Fandino AC, Casak SJ, et al. Activity of topotecan in retinoblastoma. Ophthalmic Genet 2004; 25: 37-43.
6. Leahey AM. Chemotherapy protocols. New Delhi: Jaypee Brothers Medical Publisher; 2012.
7. Chantada GL, Fandino AC, Carcaboso AM, et al. A phase I study of periocular topotecan in children with intraocular retinoblastoma. Invest Ophthalmol Vis Sci 2009; 50: 1492-1496.
8. Munier FL, Gaillard MC, Balmer A, et al. Intravitreal chemotherapy for vitreous disease in retinoblastoma revisited: From prohibition to conditional indications. Br J Ophthalmol 2012; 96: 1078-1083.
9. Abramson DH. Second nonocular cancers in retinoblastoma: A unified hypothesis. The Franceschetti Lecture. Ophthalmic Genet 1999; 20: 193-204.
10. Chantada GL, Fandino AC, Raslawski EC, et al. Experience with chemoreduction and focal therapy for intraocular retinoblastoma in a developing country. Pediatr Blood Cancer 2005; 44: 455-460.
11. Antoneli CB, Ribeiro KC, Steinhorst F, et al. Treatment of retinoblastoma patients with chemoreduction plus local therapy: Experience of the AC Camargo Hospital. Brazil J Pediatr Hematol Oncol 2006; 28: 342-345.
12. Marr BP, Dunkel IJ, Linker A, et al. Periocular carboplatin for retinoblastoma: Long-term report (12 years) on efficacy and toxicity. Br J Ophthalmol 2012; 96: 881-883.
13. Abramson DH, Dunkel IJ, Brodie SE, et al. A phase I/II study of direct intraarterial (ophthalmic artery) chemotherapy with melphalan for intraocular retinoblastoma initial results. Ophthalmology 2008; 115: 1398-1404, 404 e1.
14. Gobin YP, Dunkel IJ, Marr BP, et al. Intra-arterial chemotherapy for the management of retinoblastoma: Four-year experience. Arch Ophthalmol 2011; 129: 732-737.
15. Muen WJ, Kingston JE, Robertson F, et al. Efficacy and complications of super-selective intra-ophthalmic artery melphalan for the treatment of refractory retinoblastoma. Ophthalmology 2012; 119: 611-616.
16. Venturi C, Bracco S, Cerase A, et al. Superselective ophthalmic artery infusion of melphalan for intraocular retinoblastoma: Preliminary results from 140 treatments. Acta Ophthalmol 2012. DOI: 10.1111/j.1755-3768.2011.02296.x
17. Levin MH, Gombos DS, O'Brien JM. Intra-arterial chemotherapy for advanced retinoblastoma: Is the time right for a prospective clinical trial? Arch Ophthalmol 2011; 129: 1487-1489.
18. Abramson DH. Chemosurgery for retinoblastoma: What we know after 5 years. Arch Ophthalmol 2011; 129: 1492-1494.
19. Abramson DH, Frank CM, Dunkel IJ. A phase I/II study of subconjunctival carboplatin for intraocular retinoblastoma. Ophthalmology 1999; 106: 1947-1950.
20. Pratt CB, Kun LE. Response of orbital and central nervous system metastases of retinoblastoma following treatment with cyclophosphamide/doxorubicin. Pediatr Hematol Oncol 1987; 4: 125-130.
21. London WB, Frantz CN, Campbell LA, et al. Phase II randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: A Children's Oncology Group study. J Clin Oncol 2010; 28: 3808-3815.
22. Schaiquevich P, Buitrago E, Ceciliano A, et al. Pharmacokinetic analysis of topotecan after superselective ophthalmic artery infusion and periocular administration in a porcine model. Retina 2012; 32: 387-395.
23. Shields CL, Bianciotto CG, Jabbour P, et al. Intra-arterial chemotherapy for retinoblastoma: Report No. 1, control of retinal tumors, subretinal seeds, and vitreous seeds. Arch Ophthalmol 2011; 129: 1399-1406.
24. Shields CL, Bianciotto CG, Jabbour P, et al. Intra-arterial chemotherapy for retinoblastoma: Report No. 2, treatment complications. Arch Ophthalmol 2011; 129: 1407-1415.
25. Vajzovic LM, Murray TG, Aziz-Sultan MA. et al. Supraselective intra-arterial chemotherapy: Evaluation of treatment-related complications in advanced retinoblastoma. Clin Ophthalmol 2011; 5: 171-176.
26. Chantada GL, Dunkel IJ, Antoneli CB, et al. Risk factors for extraocular relapse following enucleation after failure of chemoreduction in retinoblastoma. Pediatr Blood Cancer 2007; 49: 256-260.
27. Vajzovic LM, Murray TG, Aziz-Sultan MA. et al. Clinicopathologic review of enucleated eyes after intra-arterial chemotherapy with melphalan for advanced retinoblastoma. Arch Ophthalmol 2010; 128: 1619-1623.
28. Eagle RC, Jr., Shields CL, Bianciotto C, et al. Histopathologic observations after intra-arterial chemotherapy for retinoblastoma. Arch Ophthalmol 2011; 129: 1416-1421.
29. Suzuki S, Yamane T, Mohri M, et al. Selective ophthalmic arterial injection therapy for intraocular retinoblastoma: The long-term prognosis. Ophthalmology 2011; 118: 2081-2087.
30. Trinavarat A, Chiewvit P, Buaboonnam J, et al. Selective ophthalmic arterial infusion of chemotherapeutic drugs for recurrent retinoblastoma. J Pediatr Hematol Oncol 2012; 34: e218-e221.