The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL

Transfusion

Volumn 53, Issue 3, 2013, Pages 539-544

  Reid, Marion E ^a   Halter Hipsky, Christine ^b   Hue Roye, Kim ^b   Coghlan, Gail ^b   Olsen, Coral ^b   Lomas Francis, Christine ^b  

^a NEW YORK BLOOD CENTER   (United States)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; RHESUS ANTIGEN; RHESUS ANTIGEN STEM; THYMINE; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; COHORT ANALYSIS; GENE; GENETIC CODE; HEMAGGLUTINATION TEST; HEMIZYGOSITY; HETEROZYGOTE; HUMAN; HUMAN CELL; PHENOTYPE; RHCE GENE; RHD GENE;

ALLELES; ANTIGENS; GENE FREQUENCY; GENE ORDER; GENETIC LINKAGE; GENOTYPE; HUMANS; PHENOTYPE; POLYMORPHISM, GENETIC; PREVALENCE; PROTEIN ISOFORMS; RH-HR BLOOD-GROUP SYSTEM;

EID: 84874946562     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2012.03754.x     Document Type: Article

References (19)

1. B-(Rh: -31, -34). Transfus Med 1993; 3: 35-41.
2. Reid ME, Lomas-Francis C,. Blood group antigen factsbook. 2nd ed. San Diego (CA): Academic Press; 2004.
3. Flegel WA,. The Rhesus site: explore the intricacies of the most complex blood group gene locus [website]. Ulm, Germany: Institut für Klinische Transfusionsmedizin und Immungenetik Ulm; 2007. [cited 2011]. Available from: URL: http://www.uni-ulm.de/%7Ewflegel/RH/
4. Human Genome Variation Society. Blood Group Antigen Gene Mutation Database [website]. 2006. [cited 2011]. Available from: URL: http://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/home
5. Westhoff CM, Vege S, Halter-Hipsky C, Whorley T, Hue-Roye K, Lomas-Francis C, Reid ME,. DIIIa and DIII Type 5 are encoded by the same allele and are associated with altered RHCE ce alleles: clinical implications. Transfusion 2010; 50: 1303-11.
6. Reid ME, Storry JR, Sausais L, Tossas E, Rios M, Hue-Roye K, Gloster ES, Miller ST, Wolf C, Lomas-Francis C,. DAK, a new low-incidence antigen in the Rh blood group system. Transfusion 2003; 43: 1394-7.
7. Halter-Hipsky C, Hue-Roye K, Coghlan G, Lomas-Francis C, Reid ME,. Two alleles with RHCEE*nt818C>T change encode the low prevalence Rh antigen STEM. Blood 2009; 114: 1226-7.
8. B+, STEM+ phenotype. Transfusion 2010; 50: 48A.
9. Halter Hipsky C, da Costa DC, Omoto R, Zanette A, Castilho L, Reid ME,. Prevalence of RHDE*DOL and RHCEE*ce(818T) in two populations. Immunohematology 2011; 27: 66-7.
10. Noizat-Pirenne F, Lee K, Le Pennec PY, Simon P, Kazup P, Bachir D, Rousaud AM, Roussel M, Juszczak G, Ménanteau C, Rouger P, Cartron JP, Ansart-Pirenne H,. Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety. Blood 2002; 100: 4223-31.
11. Halter Hipsky C, Lomas-Francis C, Fuchisawa A, Reid ME, Moulds M, Christensen J, Nickle P, Vege S, Westhoff C,. RHCE ceCF encodes partial c and partial e but not CELO, an antigen antithetical to Crawford. Transfusion 2011; 51: 25-31.
12. Halter Hipsky C, Hue-Roye K, Lomas-Francis C, Huang CH, Reid ME,. Molecular basis of the rare gene complex, DIV(C)-, which encodes four low prevalence antigens in the Rh blood group system. Vox Sang 2012; 102: 167-70.
13. Perco P, Shao CP, Mayr WR, Panzer S, Legler TJ,. Testing for the D zygosity with three different methods revealed altered Rhesus boxes and a new weak D type. Transfusion 2003; 43: 335-9.
14. Denomme G, Fernandes BJ,. The assignment of RHD gene zygosity by densitometric quantification. Transfusion 1999; 39: 51s.
15. Wagner FF, Moulds JM, Tounkara A, Kouriba B, Flegel WA,. RHD allele distribution in Africans of Mali. BMC Genet 2003; 4: 14.
16. Matheson KA, Denomme GA,. Novel 3′Rhesus box sequences confound RHD zygosity assignment. Transfusion 2002; 42: 645-50.
17. Halter Hipsky C, Velliquette RW, Larimore K, Olsen C, Lomas-Francis C, Reid ME,. Molecular background of RHCE in Bastiaan, the RH:-31,-34 index case, and two novel RHD alleles. Immunohematology. In press.
18. B. Transfusion 2010; 50: 144A.
19. Hue-Roye K, Reid ME, Westhoff CM, Lomas-Francis C,. Red cells from the original JAL+ proband are also DAK+ and STEM+. Vox Sang 2011; 101: 61-4.