Gold nanoparticle aerosols for rodent inhalation and translocation studies

Journal of Nanoparticle Research

Volumn 15, Issue 4, 2013, Pages

  Möller, Winfried ^a   Gibson, Neil ^b   Geiser, Marianne ^c   Pokhrel, Suman ^d   Wenk, Alexander ^a   Takenaka, Shinji ^a   Schmid, Otmar ^a   Bulgheroni, Antonio ^b   Simonelli, Federica ^b   Kozempel, Jan ^b   Holzwarth, Uwe ^b   Wigge, Christoph ^c   Eigeldinger Berthou, Sylvie ^c   Mädler, Lutz ^d   Kreyling, Wolfgang G ^a  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b JOINT RESEARCH CENTRE   (Italy)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF BREMEN   (Germany)

Author keywords

Au 195 radiolabel; Chain aggregate agglomerate; Gold nanoparticles; Proton irradiation; Spark ignition; X ray diffraction

Indexed keywords

AEROSOLS; BIOLOGICAL ORGANS; GAMMA RAYS; GOLD NANOPARTICLES; MAMMALS; METAL NANOPARTICLES; MORPHOLOGY; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; PROTON IRRADIATION; RISK ASSESSMENT; SAFE HANDLING; SPECIFIC SURFACE AREA; X RAY DIFFRACTION;

CHAIN AGGREGATES; CHEMICAL COMPOSITIONS; GEOMETRIC STANDARD DEVIATIONS; NANO-SIZED PARTICLES; NANOPARTICLE AEROSOLS; NUMBER CONCENTRATION; RADIOLABEL; SPARK IGNITION;

GOLD METALLOGRAPHY;

GOLD NANOPARTICLE; SILICON DIOXIDE;

AEROSOL; ARTICLE; CHEMICAL COMPOSITION; CRYSTAL STRUCTURE; DOSIMETRY; GAMMA RADIATION; HALF LIFE TIME; IN VIVO STUDY; ISOTOPE LABELING; LIMIT OF DETECTION; LUNG ALVEOLUS CELL; LUNG PARENCHYMA; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RADIOACTIVITY; RISK ASSESSMENT; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION;

EID: 84874939239     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-013-1574-9     Document Type: Article

References (39)

1. Alessandrini F, Semmler-Behnke M, Jakob T, Schulz H, Behrendt H, Kreyling W (2008) Total and regional deposition of ultrafine particles in a mouse model of allergic inflammation of the lung. Inhal Toxicol 20(6):585-593 (Pubitemid 351601403)
2. Arvizo R, Bhattacharya R, Mukherjee P (2010) Gold nanoparticles: opportunities and challenges in nanomedicine. Expert Opin Drug Deliv 7(6):753-763. doi: 10.1517/17425241003777010
3. Baron PA, Willeke K (2001) Aerosol measurement: principles, techniques, and applications, 2nd edn. Wiley, New York
4. Baumeister W (2002) Electron tomography: towards visualizing the molecular organization of the cytoplasm. Curr Opin Struct Biol 12(5):679-684 (Pubitemid 35449079)
5. Buffat P, Borel JP (1976) Size effect on the melting temperature of gold particles. Phys Rev A 13(6):2287-2298
6. Doane TL, Burda C (2012) The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy. Chem Soc Rev 41(7):2885-2911. doi: 10.1039/C2cs15260f
7. Donaldson K, Stone V, Tran CL, Kreyling W, Borm PJA (2004) Nanotoxicology. Occup Environ Med 61(9):727-728 (Pubitemid 39178799)
8. Ferin J, Oberdörster G, Penney DP (1992) Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6(5):535-542
9. Fierz M, Kaegi R, Burtscher H (2007) Theoretical and experimental evaluation of a portable electrostatic TEM sampler. Aerosol Sci Technol 41(5):520-528
10. Firestone RB, Ekström LP (2004) WWW table of radioactive isotopes. LBNL Isotopes Project - LUNDS Universitet, vol 2.1. Lund University, Lund, Sweden
11. Geiser M, Kreyling W (2010) Deposition and biokinetics of inhaled nanoparticles. Part Fibre Toxicol 7(1):2
12. Geiser M, Rothen-Rutishauser B, Kapp N, Schurch S, Kreyling W, Schulz H, Semmler M, Hof VI, Heyder J, Gehr P (2005) Ultrafine particles cross cellular membranes by nonphagocytic mechanisms in lungs and in cultured cells. Environ Health Perspect 113(11):1555-1560 (Pubitemid 41614911)
13. Geiser M, Casaulta M, Kupferschmid B, Schulz H, Semmler-Behnke M, Kreyling W (2008) The role of macrophages in the clearance of inhaled ultrafine titanium dioxide particles. Am J Respir Cell Mol Biol 38(3):371-376 (Pubitemid 351567707)
14. George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Madler L, Nel AE (2010) Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano 4(1):15-29. doi: 10.1021/nn901503q
15. Gibson PN, Özsan ME, Lincot D, Cowache P, Summa D (2000) Modelling of the structure of CdS thin films. Thin Solid Films 361-362:34-40. doi: 10.1016/s0040-6090(99)00833-0 (Pubitemid 30552356)
16. Hainfeld JF, Slatkin DN, Focella TM, Smilowitz HM (2006) Gold nanoparticles: a new X-ray contrast agent. Br J Radiol 79(939):248-253
17. Holzwarth U, Bulgheroni A, Gibson N, Kozempel J, Cotogno G, Abbas K, Simonelli F, Cydzik I (2012) Radiolabelling of nanoparticles by proton irradiation: temperature control in nanoparticulate powder targets. J Nanopart Res 14(6):1-15. doi: 10.1007/s11051-012-0880-y
18. Kreuter J (2004) Influence of the surface properties on nanoparticle-mediated transport of drugs to the brain. J Nanosci Nanotech 4(5):484-488 (Pubitemid 39387399)
19. Kreyling W, Biswas P, Messing M, Gibson N, Geiser M, Wenk A, Sahu M, Deppert K, Cydzik I, Wigge C, Schmid O, Semmler-Behnke M (2011) Generation and characterization of stable, highly concentrated titanium dioxide nanoparticle aerosols for rodent inhalation studies. J Nanopart Res 13(2):511-524. doi: 10.1007/s11051-010-0081-5
20. Kreyling WG, Semmler-Behnke M, Takenaka S, Möller W (2013) Differences in the biokinetics of inhaled nano-versus micrometer-sized particles. Accounts Chem Res (in press). doi: 10.1021/ar300043r
21. Kuehl PJ, Anderson TL, Candelaria G, Gershman B, Harlin K, Hesterman JY, Holmes T, Hoppin J, Lackas C, Norenberg JP, Yu H, McDonald JD (2012) Regional particle size dependent deposition of inhaled aerosols in rats and mice. Inhal Toxicol 24(1):27-35. doi: 10.3109/08958378.2011.632787
22. Liu Z, Kim SC, Wang J, Shin WG, Fissan H, Pui DYH (2012) Measurement of metal nanoparticle agglomerates generated by spark discharge using the universal nanoparticle analyzer (UNPA). Aerosol Sci Technol 46(3):333-346. doi: 10.1080/02786826.2011.626002
23. Ma-Hock L, Gamer AO, Landsiedel R, Leibold E, Frechen T, Sens B, Linsenbuehler M, van Ravenzwaay B (2007) Generation and characterization of test atmospheres with nanomaterials. Inhal Toxicol 19(10):833-848 (Pubitemid 47237751)
24. Maynard AD, Aitken RJ, Butz T, Colvin V, Donaldson K, Oberdörster G, Philbert MA, Ryan J, Seaton A, Stone V, Tinkle SS, Tran L, Walker NJ, Warheit DB (2006) Safe handling of nanotechnology. Nature 444(7117):267-269 (Pubitemid 44764087)
25. Moghimi SM, Hunter AC, Murray JC (2005) Nanomedicine: current status and future prospects. FASEB J 19(3):311-330 (Pubitemid 40316520)
26. Nel A, Xia T, Madler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622-627 (Pubitemid 43191298)
27. Nel AE, Mädler L, Velegol D, Xia T, Hoek EMV, Somasundaran P, Klaessig F, Castranova V, Thompson M (2009) Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 8(7):543-557
28. Oberdörster G, Oberdörster E, Oberdörster J (2005) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823-839 (Pubitemid 40984181)
29. Papasani MR, Wang G, Hill RA (2012) Gold nanoparticles: the importance of physiological principles to devise strategies for targeted drug delivery. Nanomedicine (Lond). doi: 10.1016/j.nano.2012.01.008
30. Peters A, Veronesi B, Calderon-Garciduenas L, Gehr P, Chen L, Geiser M, Reed W, Rothen-Rutishauser B, Schurch S, Schulz H (2006) Translocation and potential neurological effects of fine and ultrafine particles a critical update. Part Fibre Toxicol 3(1):13 (Pubitemid 44468855)
31. Porter D, Sriram K, Wolfarth M, Jefferson A, Schwegler-Berry D, Andrew ME, Castranova V (2008) A biocompatible medium for nanoparticle dispersion. Nanotoxicology 2(3):144-154
32. Rand D, Ortiz V, Liu Y, Derdak Z, Wands JR, Tatíček M, Rose-Petruck C (2011) Nanomaterials for X-ray imaging: gold nanoparticle enhancement of X-ray scatter imaging of hepatocellular carcinoma. Nano Lett 11(7):2678-2683. doi: 10.1021/nl200858y
33. Seaton A, Donaldson K (2005) Nanoscience, nanotoxicology, and the need to think small. Lancet 365(9463):923-924 (Pubitemid 41071418)
34. Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, Takenaka S, Schmid G, Brandau W (2008) Biodistribution of 1.4- and 18-nm gold particles in rats. Small 4(12):2108-2111. doi: 10.1002/smll.200800922
35. Stoeger T, Reinhard C, Takenaka S, Schroeppel A, Karg E, Ritter B, Heyder J, Schulz H (2006) Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice. Environ Health Perspect 114(3):328-333 (Pubitemid 43338255)
36. Takenaka S, Karg E, Kreyling WG, Lentner B, Möller W, Behnke-Semmler M, Jennen L, Walch A, Michalke B, Schramel P, Heyder J, Schulz H (2006) Distribution pattern of inhaled ultrafine gold particles in the rat lung. Inhal Toxicol 18(10):733-740
37. Takenaka S, Möller W, Semmler-Behnke M, Karg E, Wenk A, Schmid O, Stoeger T, Jennen L, Aichler M, Walch A, Pokhrel S, Mädler L, Eickelberg O, Kreyling WG (2012) Efficient internalization and intracellular translocation of inhaled gold nanoparticles in rat alveolar macrophages. Nanomedicine (Lond) 7:855-865. doi: 10.2217/nnm.11.152
38. Wilson BJ (1966) The radiochemical manual, 2nd edn. Radiochemical Centre, Amersham
39. Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao Y-P, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE (2012) Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano 6(5):4349-4368. doi: 10.1021/nn3010087