UbcH10 overexpression in human lung carcinomas and its correlation with EGFR and p53 mutational status

European Journal of Cancer

Volumn 49, Issue 5, 2013, Pages 1117-1126

  Pallante, Pierlorenzo ^a   Malapelle, Umberto ^b   Berlingieri, Maria Teresa ^a   Bellevicine, Claudio ^b   Sepe, Romina ^a   Federico, Antonella ^a   Rocco, Danilo ^c   Galgani, Mario ^a   Chiariotti, Lorenzo ^a   Sanchez Cespedes, Montserrat ^d   Fusco, Alfredo ^a   Troncone, Giancarlo ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c Azienda Ospedaliera di Rilievo Nazionale v Monaldi   (Italy)

^d HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Diagnosis; Immunohistochemistry; Non small cell lung cancer; UbcH10

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN P53; UBIQUITIN CONJUGATING ENZYME E2;

ARTICLE; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER PROGNOSIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG CARCINOMA; LUNG NON SMALL CELL CANCER; LUNG PARENCHYMA; LUNG SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY;

CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DNA MUTATIONAL ANALYSIS; EPISTASIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; LUNG NEOPLASMS; MALE; MUTATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UBIQUITIN-CONJUGATING ENZYMES;

EID: 84874936370     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.09.033     Document Type: Article

References (36)

1. S. Walker Updates in non-small cell lung cancer Clin J Oncol Nurs 12 2008 587 596
2. D.C. Christiani Genetic susceptibility to lung cancer J Clin Oncol 24 2006 1651 1652
3. S. Sun, J.H. Schiller, and A.F. Gazdar Lung cancer in never smokers-a different disease Nat Rev Cancer 7 2007 778 790
4. A. Spira, and D.S. Ettinger Multidisciplinary management of lung cancer N Engl J Med 350 2004 379 392
5. R. Meuwissen, and A. Berns Mouse models for human lung cancer Genes Dev 19 2005 643 664
6. S.W. Lowe, and C.J. Sherr Tumor suppression by Ink4a-Arf: progress and puzzles Curr Opin Genet Dev 13 2003 77 83
7. Y.P. Sher, C.C. Chou, and R.H. Chou Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness Cancer Res 66 2006 11763 11770
8. G. Rossi, G. Pelosi, P. Graziano, M. Barbareschi, and M. Papotti A reevaluation of the clinical significance of histological subtyping of non-small-cell lung carcinoma: diagnostic algorithms in the era of personalized treatments Int J Surg Pathol 17 2009 206 218
9. Y. Okamoto, T. Ozaki, K. Miyazaki, M. Aoyama, M. Miyazaki, and A. Nakagawara UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme Cancer Res 63 2003 4167 4173
10. Y. Lin, W.C. Hwang, and R. Basavappa Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10 J Biol Chem 277 2002 21913 21921
11. M. Rape, and M.W. Kirschner Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry Nature 432 2004 588 595
12. A. de Gramont, O. Ganier, and O. Cohen-Fix Before and after the spindle assembly checkpoint-an APC/C point of view Cell Cycle 5 2006 2168 2171
13. P. Pallante, M.T. Berlingieri, and G. Troncone UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas Br J Cancer 93 2005 464 471
14. M.T. Berlingieri, P. Pallante, and A. Sboner UbcH10 is overexpressed in malignant breast carcinomas Eur J Cancer 43 2007 2729 2735
15. M.T. Berlingieri, P. Pallante, and M. Guida UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomas Oncogene 26 2007 2136 2140
16. S.M. Chen, C.Y. Jiang, and J.Y. Wu RNA interference-mediated silencing of UBCH10 gene inhibits colorectal cancer cell growth in vitro and in vivo Clin Exp Pharmacol Physiol 37 2010 525 529
17. G. Donato, G. Iofrida, and A. Lavano Analysis of UbcH10 expression represents a useful tool for the diagnosis and therapy of astrocytic tumors Clin Neuropathol 27 2008 219 223
18. G. Troncone, E. Guerriero, and P. Pallante UbcH10 expression in human lymphomas Histopathology 54 2009 731 740
19. B. Angulo, A. Suarez-Gauthier, and F. Lopez-Rios Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification J Pathol 214 2008 347 356
20. W.D. Travis, E. Brambilla, H.K. Müller-Hermelink, and C.C. Harris Pathology and genetics of tumours of lung, pleura, thymus and heart W.D. Travis, World Health Organization Classification of Tumours 2004 IARC Press Lyon 9 122
21. C. Quintavalle, M. Incoronato, and L. Puca C-FLIPL enhances anti-apoptotic Akt functions by modulation of Gsk3beta activity Cell Death Differ 17 2010 1908 1916
22. C. Quintavalle, M. Garofalo, and C. Zanca MiR-221/222 overexpression in human glioblastoma increases invasiveness by targeting the protein phosphate PTPmu Oncogene 31 2011 858 868
23. S. Toyooka, T. Tsuda, and A.F. Gazdar The TP53 gene, tobacco exposure, and lung cancer Hum Mutat 21 2003 229 239
24. Y. Sekido, K.M. Fong, and J.D. Minna Molecular genetics of lung cancer Annu Rev Med 54 2003 73 87
25. D.G. Beer, S.L. Kardia, and C.C. Huang Gene-expression profiles predict survival of patients with lung adenocarcinoma Nat Med 8 2002 816 824
26. C.A. Granville, and P.A. Dennis An overview of lung cancer genomics and proteomics Am J Respir Cell Mol Biol 32 2005 169 176
27. M.S. Tsao, A. Sakurada, and J.C. Cutz Erlotinib in lung cancer-molecular and clinical predictors of outcome N Engl J Med 353 2005 133 144
28. D.A. Wigle, I. Jurisica, and N. Radulovich Molecular profiling of non-small cell lung cancer and correlation with disease-free survival Cancer Res 62 2002 3005 3008
29. H. Endoh, S. Tomida, and Y. Yatabe Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction J Clin Oncol 22 2004 811 819
30. J.D. Hoheisel Microarray technology: beyond transcript profiling and genotype analysis Nat Rev Genet 7 2006 200 210
31. S.S. Han, Q.G. Liu, and Y.M. Yao UbcH10 expression in hepatocellular carcinoma and its clinicopathological significance Nan Fang Yi Ke Da Xue Xue Bao 31 2011 280 284
32. T. Fujita, H. Ikeda, and K. Kawasaki Clinicopathological relevance of UbcH10 in breast cancer Cancer Sci 100 2009 238 248
33. T. Fujita, H. Ikeda, N. Taira, S. Hatoh, M. Naito, and H. Doihara Overexpression of UbcH10 alternates the cell cycle profile and accelerate the tumor proliferation in colon cancer BMC Cancer 9 2009 87
34. G. Troncone, M. Volante, and A. Iaccarino Cyclin D1 and D3 overexpression predicts malignant behavior in thyroid fine-needle aspirates suspicious for Hurthle cell neoplasms Cancer Cytopathol 117 2009 522 529
35. D.M. Feldser, K.K. Kostova, and M.M. Winslow Stage-specific sensitivity to p53 restoration during lung cancer progression Nature 468 2010 572 575
36. J. Lukas, and J. Bartek Cell division: the heart of the cycle Nature 432 2004 564 567