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Volumn 32, Issue SUPP2, 2012, Pages 21-29

Iron and infection: Narrative review of a major iron supplementation study in Papua New Guinea undertaken by the Department of Tropical Paediatrics, Liverpool School of Tropical Medicine, 1979-1983, its aftermath and the continuing relevance of its results

Author keywords

Infection; Iron; Malaria; Meta analysis; Trials

Indexed keywords

FOLIC ACID; IRON; IRON DEXTRAN; ZINC;

EID: 84874891497     PISSN: 20469047     EISSN: 20469055     Source Type: Journal    
DOI: 10.1179/2046904712Z.00000000075     Document Type: Article
Times cited : (5)

References (46)
  • 1
  • 2
    • 0035146949 scopus 로고    scopus 로고
    • Iron and its relation to immunity and infectious disease
    • Oppenheimer SJ. Iron and its relation to immunity and infectious disease. J Nutr. 2001;131:616-33S.
    • (2001) J Nutr , vol.131 , pp. 616-633
    • Oppenheimer, S.J.1
  • 4
    • 0023008228 scopus 로고
    • Effect of iron prophylaxis on morbidity due to infectious disease: Report on clinical studies in Papua New Guinea
    • Oppenheimer SJ, Macfarlane SB, Moody JB, Bunari O, Hendrickse RG. Effect of iron prophylaxis on morbidity due to infectious disease: report on clinical studies in Papua New Guinea. Trans R Soc Trop Med Hyg. 1986;80:596-602.
    • (1986) Trans R Soc Trop Med Hyg , vol.80 , pp. 596-602
    • Oppenheimer, S.J.1    Macfarlane, S.B.2    Moody, J.B.3    Bunari, O.4    Hendrickse, R.G.5
  • 6
    • 0021737519 scopus 로고
    • Iron and infection in infancy. Report of field studies in Papua New Guinea. 2. Protocol and description of study cohort
    • Oppenheimer SJ, Hendrickse RG, Macfarlane SBJ, Moody JB, Harrison C, Alpers M. et al. Iron and infection in infancy. Report of field studies in Papua New Guinea. 2. Protocol and description of study cohort. Ann Trop Paediatr. 1984;4:145-53.
    • (1984) Ann Trop Paediatr , vol.4 , pp. 145-153
    • Oppenheimer, S.J.1    Hendrickse, R.G.2    Macfarlane, S.B.J.3    Moody, J.B.4    Harrison, C.5    Alpers, M.6
  • 7
    • 0021669106 scopus 로고
    • Iron and infection in infancy. Report on field studies in Papua New Guinea. 1. Demographic description and pilot surveys
    • Oppenheimer SJ, Macfarlane SBJ, Moody, JB, Bunari O, Williams TE, Harrison C, et al. Iron and infection in infancy. Report on field studies in Papua New Guinea. 1. Demographic description and pilot surveys. Ann Trop Paediatr. 1984;4:135-43.
    • (1984) Ann Trop Paediatr , vol.4 , pp. 135-143
    • Oppenheimer, S.J.1    Macfarlane, S.B.J.2    Moody, J.B.3    Bunari, O.4    Williams, T.E.5    Harrison, C.6
  • 8
    • 0017671012 scopus 로고
    • Increased incidence of gram-negative neonatal sepsis with intramuscular iron administration
    • Barry DMJ, Reeve AW. Increased incidence of gram-negative neonatal sepsis with intramuscular iron administration. Pediatrics. 1977;60:908-12.
    • (1977) Pediatrics , vol.60 , pp. 908-912
    • Barry, D.M.J.1    Reeve, A.W.2
  • 9
    • 0014688946 scopus 로고
    • Impaired opsonic activity but normal phagocytosis in low-birth-weight infants
    • Forman ML, Stiehm ER. Impaired opsonic activity but normal phagocytosis in low-birth-weight infants. N Engl J Med. 1969;281:926-31.
    • (1969) N Engl J Med , vol.281 , pp. 926-931
    • Forman, M.L.1    Stiehm, E.R.2
  • 11
    • 0025899243 scopus 로고
    • The effect of insecticide-treated bed nets on mortality of Gambian children
    • Alonso PL, Lindsay SW, Armstrong JRM. The effect of insecticide-treated bed nets on mortality of Gambian children. Lancet. 1991;337:1499-502.
    • (1991) Lancet , vol.337 , pp. 1499-1502
    • Alonso, P.L.1    Lindsay, S.W.2    Armstrong, J.R.M.3
  • 12
    • 30444460600 scopus 로고    scopus 로고
    • Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: Community-based, cluster-randomised, placebo-controlled trial
    • Tielsch JM, Khatry SK, Stoltzfus RJ, Katz J, LeClerq SC, Adhikari R. et al. Effect of routine prophylactic supplementation with iron and folic acid on preschool child mortality in southern Nepal: community-based, cluster-randomised, placebo-controlled trial. Lancet. 2006;367:144-52.
    • (2006) Lancet , vol.367 , pp. 144-152
    • Tielsch, J.M.1    Khatry, S.K.2    Stoltzfus, R.J.3    Katz, J.4    LeClerq, S.C.5    Adhikari, R.6
  • 14
    • 0024834036 scopus 로고
    • Iron and infection: The clinical evidence
    • Oppenheimer SJ. Iron and infection: the clinical evidence. Acta Paediatr Scand. 1989;361:S53-62.
    • (1989) Acta Paediatr Scand , vol.361
    • Oppenheimer, S.J.1
  • 15
    • 85172058820 scopus 로고
    • A re-evaluation of the potential risks of iron therapy in childhood
    • Oppenheimer SJ. A re-evaluation of the potential risks of iron therapy in childhood. Postgrad Doct Afr. 1991;13:92-4.
    • (1991) Postgrad Doct Afr , vol.13 , pp. 92-94
    • Oppenheimer, S.J.1
  • 17
    • 38549161207 scopus 로고
    • Interactions of malaria with nutrition
    • Oppenheimer SJ. Interactions of malaria with nutrition. Hong Kong J Paediatr. 1992;9:5-14.
    • (1992) Hong Kong J Paediatr , vol.9 , pp. 5-14
    • Oppenheimer, S.J.1
  • 19
    • 0031725702 scopus 로고    scopus 로고
    • Iron and infection in the tropics: Paediatric clinical correlates
    • Oppenheimer SJ. Iron and infection in the tropics: paediatric clinical correlates. Ann Trop Paediatr. 1998;18:S81-7.
    • (1998) Ann Trop Paediatr , vol.18
    • Oppenheimer, S.J.1
  • 20
    • 0037121352 scopus 로고    scopus 로고
    • Effect of iron supplementation on incidence of infectious illness in children: Systematic review
    • Gera T, Sachdev HP. Effect of iron supplementation on incidence of infectious illness in children: systematic review. Br Med J. 2002;325:1142-51.
    • (2002) Br Med J , vol.325 , pp. 1142-1151
    • Gera, T.1    Sachdev, H.P.2
  • 21
    • 70049105108 scopus 로고    scopus 로고
    • Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas
    • doi:10.1002/14651858.CD006589.pub2
    • Ojukwu JU, Okebe JU, Yahav D, Paul M. Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas. Cochrane Database Syst Rev. 2009; doi:10.1002/14651858.CD006589.pub2.
    • (2009) Cochrane Database Syst Rev
    • Ojukwu, J.U.1    Okebe, J.U.2    Yahav, D.3    Paul, M.4
  • 22
    • 0000473019 scopus 로고
    • Anaemia in infancy; its prevalence and prevention
    • Mackay HM. Anaemia in infancy; its prevalence and prevention. Arch Dis Child. 1928;3:117-47.
    • (1928) Arch Dis Child , vol.3 , pp. 117-147
    • Mackay, H.M.1
  • 23
    • 0013868093 scopus 로고
    • Utilization of dietary iron by term infants. A study of 1,048 infants from a low socioeconomic population
    • Andelman MB, Sered BR. Utilization of dietary iron by term infants. A study of 1,048 infants from a low socioeconomic population. Am J Dis Child. 1966;111:45-55.
    • (1966) Am J Dis Child , vol.111 , pp. 45-55
    • Andelman, M.B.1    Sered, B.R.2
  • 26
    • 0029148124 scopus 로고
    • Effect of supplementation with an iron-fortified milk on incidence of diarrhea and respiratory infection in urban resident infants
    • Heresi G, Pizarro F, Olivares M, Cayazzo M, Hertrampf E, Walter T, et al. Effect of supplementation with an iron-fortified milk on incidence of diarrhea and respiratory infection in urban resident infants. Scand J Infect Dis. 1995;27:385-9.
    • (1995) Scand J Infect Dis , vol.27 , pp. 385-389
    • Heresi, G.1    Pizarro, F.2    Olivares, M.3    Cayazzo, M.4    Hertrampf, E.5    Walter, T.6
  • 27
    • 0030771313 scopus 로고    scopus 로고
    • Long-term oral supplementation with iron is not harmful for young children in a poor community of Bangladesh
    • Mitra AK, Akramuzzaman SM, Fuchs GJ, Rahman MM, Mahalanabis D. Long-term oral supplementation with iron is not harmful for young children in a poor community of Bangladesh. J Nutr. 1997;127:1451-5.
    • (1997) J Nutr , vol.127 , pp. 1451-1455
    • Mitra, A.K.1    Akramuzzaman, S.M.2    Fuchs, G.J.3    Rahman, M.M.4    Mahalanabis, D.5
  • 28
    • 85172051698 scopus 로고    scopus 로고
    • Proceedings of the Belmont Conference, 21-24 May 2000, Belmont, MD
    • Iron Deficiency Anemia: Reexamining the Nature and Magnitude of the Public Health Problem
    • Iron Deficiency Anemia: Reexamining the Nature and Magnitude of the Public Health Problem. Proceedings of the Belmont Conference, 21-24 May 2000, Belmont, MD. J Nutr. 2001;131:563-703S.
    • (2001) J Nutr , vol.131 , pp. 563-703
  • 29
    • 0035146892 scopus 로고    scopus 로고
    • An analysis of anemia and child mortality
    • Brabin BJ, Premji Z, Verhoeff F. An analysis of anemia and child mortality. J Nutr. 2001;131 (2S-2):636-45S.
    • (2001) J Nutr , vol.131 , Issue.2 S2 , pp. 636-645
    • Brabin, B.J.1    Premji, Z.2    Verhoeff, F.3
  • 30
    • 0035150385 scopus 로고    scopus 로고
    • Defining iron-deficiency anemia in public health terms: A time for reflection
    • Stoltzfus RJ. Defining iron-deficiency anemia in public health terms: a time for reflection. J Nutr. 2001;131 (2S-2):565-7S.
    • (2001) J Nutr , vol.131 , Issue.2 S2 , pp. 565-577
    • Stoltzfus, R.J.1
  • 31
    • 0030882089 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for the prevention of severe anaemia and malaria in Tanzanian infants
    • Menendez C, Kahigwa E, Hirt R, Vounatsou P, Aponte JJ, Font F, et al. Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for the prevention of severe anaemia and malaria in Tanzanian infants. Lancet. 1997;350:844-50.
    • (1997) Lancet , vol.350 , pp. 844-850
    • Menendez, C.1    Kahigwa, E.2    Hirt, R.3    Vounatsou, P.4    Aponte, J.J.5    Font, F.6
  • 32
    • 85172063646 scopus 로고    scopus 로고
    • 1999, Accessed 1 July, INACG Consensus Statement, Washington, DC: ILSI
    • INACG Consensus Statement. Safety of Iron Supplementation Programs in Malaria-Endemic Regions. Washington, DC: ILSI, 1999. http://www.ilsi.org/ResearchFoundation/Publications/SafetyofIronSupp_Malaria.pdf Accessed 1 July, 2011.
    • (2011) Safety of Iron Supplementation Programs in Malaria-Endemic Regions
  • 33
    • 85172052968 scopus 로고    scopus 로고
    • International Life Sciences Institute, Accessed 1 July 2011
    • International Life Sciences Institute. Research Foundation. INACG and IVACG. http://www.ilsi.org/ResearchFoundation/Pages/INACG-IVACG.aspx Accessed 1 July 2011.
    • Research Foundation. INACG and IVACG
  • 34
    • 30444459334 scopus 로고    scopus 로고
    • Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: Community-based, randomised, placebo-controlled trial
    • Sazawal S, Black RE, Ramsan M, Chwaya HM, Stoltzfus RJ, Dutta A, et al. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebo-controlled trial. Lancet. 2006;367:133-43.
    • (2006) Lancet , vol.367 , pp. 133-143
    • Sazawal, S.1    Black, R.E.2    Ramsan, M.3    Chwaya, H.M.4    Stoltzfus, R.J.5    Dutta, A.6
  • 35
    • 85172043527 scopus 로고    scopus 로고
    • 2005, Accessed 1. July, World Health Organization/UNICEF/IVACG Task Force, Sommer A, ed. 1. Report of a WHO/UNICEF/IVACG meeting, Florence, Italy, 17-20 April Available at
    • World Health Organization/UNICEF/IVACG Task Force. Innocenti Micronutrient Research Report #1. Sommer A, ed. 1. Report of a WHO/UNICEF/IVACG meeting, Florence, Italy, 17-20 April 2005. Available at: http://www.micronutrientforum. org/PDF/InnocentiMicronutrientResearchReport_1.pdf: Accessed 1. July 2011.
    • (2011) Innocenti Micronutrient Research Report #1
  • 36
    • 30444453841 scopus 로고    scopus 로고
    • Comment: Iron and folic acid supplementation and malaria risk
    • English M, Snow RW. Comment: Iron and folic acid supplementation and malaria risk. Lancet. 2006;367:90-1.
    • (2006) Lancet , vol.367 , pp. 90-91
    • English, M.1    Snow, R.W.2
  • 38
    • 38549119493 scopus 로고    scopus 로고
    • Comments on expert papers related to iron, folate, malaria and other infection. The WHO Expert Consultation on Prevention and Control of Iron Deficiency in Children from Various Environments, Lyon, 2006
    • Oppenheimer S. Comments on expert papers related to iron, folate, malaria and other infection. The WHO Expert Consultation on Prevention and Control of Iron Deficiency in Children from Various Environments, Lyon, 2006. Food Nutr Bull. 2007;28:S550-9.
    • (2007) Food Nutr Bull , vol.28
    • Oppenheimer, S.1
  • 39
    • 38549164231 scopus 로고    scopus 로고
    • Mechanism of iron toxicity
    • Hershko C. Mechanism of iron toxicity. Food Nutr Bull. 2007;28:S500-9.
    • (2007) Food Nutr Bull , vol.28
    • Hershko, C.1
  • 40
    • 84874864046 scopus 로고    scopus 로고
    • Commentary on 'Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas' with a response from the Cochrane reviewers
    • doi: 10.1002/ebch.505
    • Roth DE, Black RE. Commentary on 'Oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas' with a response from the Cochrane reviewers. Evid Based Child Health. 2010;5:1186-8. doi: 10.1002/ebch.505
    • (2010) Evid Based Child Health , vol.5 , pp. 1186-1188
    • Roth, D.E.1    Black, R.E.2
  • 41
    • 79955501856 scopus 로고    scopus 로고
    • Commentary: Cochrane Review on oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas
    • Stoltzfus R. Commentary: Cochrane Review on oral iron supplementation for preventing or treating anaemia among children in malaria-endemic areas. Int J Epidemiol. 2010;39:32-5.
    • (2010) Int J Epidemiol , vol.39 , pp. 32-35
    • Stoltzfus, R.1
  • 42
    • 0030931452 scopus 로고    scopus 로고
    • Editorial: Meta-analysis and the meta-epidemiology of clinical research: Meta-analysis is an important contribution to research and practice but it's not a panacea
    • Naylor CD. Editorial: Meta-analysis and the meta-epidemiology of clinical research: meta-analysis is an important contribution to research and practice but it's not a panacea. Br Med J. 1997;315:617.
    • (1997) Br Med J , vol.315 , pp. 617
    • Naylor, C.D.1


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