A randomized controlled trial of 1% aqueous chlorhexidine gluconate compared with 10% povidone-iodine for topical antiseptic in neonates: Effects on blood culture contamination rates

Infection Control and Hospital Epidemiology

Volumn 34, Issue 4, 2013, Pages 430-432

  Nuntnarumit, Pracha ^a   Sangsuksawang, Nartsiri ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORHEXIDINE GLUCONATE; POVIDONE IODINE;

ARTICLE; BACTERIUM CONTAMINATION; BLOOD CULTURE; BURN; CONTACT DERMATITIS; CONTROLLED STUDY; DRUG EFFICACY; ERYTHEMA; HUMAN; NEWBORN; RANDOMIZED CONTROLLED TRIAL; SKIN FLORA; STAPHYLOCOCCUS EPIDERMIDIS;

ADMINISTRATION, CUTANEOUS; ANTI-INFECTIVE AGENTS, LOCAL; ANTISEPSIS; BLOOD; BLOOD SPECIMEN COLLECTION; CHLORHEXIDINE; HUMANS; INFANT, NEWBORN; OUTCOME ASSESSMENT (HEALTH CARE); POVIDONE-IODINE; SKIN; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 84874888720     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/669863     Document Type: Article

References (10)

1. Bates DW, Goldman L, Lee TH. Contaminant blood cultures and resource utilization: the true consequences of false-positive results. JAMA 1991;265:365-369.
2. Suwanpimolkul G, Pongkumpai M, Suankratay C. A randomized trial of 2% chlorhexidine tincture compared with 10% aqueous povidone-iodine for venipuncture site disinfection: effects on blood culture contamination rates. J Infect 2008;56:354-359.
3. Linder N, Prince S, Barzilai A, et al. Disinfection with 10% povidone-iodine versus 0.5% chlorhexidine gluconate in 70% isopropanol in the neonatal intensive care unit. Acta Paediatr 2004;93:205-210.
4. Lim KS, Kam PC. Chlorhexidine-pharmacology and clinical applications. Anaesth Intensive Care 2008;36:502-512.
5. Caldeira D, David C, Sampaio C. Skin antiseptics in venous puncture-site disinfection for prevention of blood culture contamination: systematic review with meta-analysis. J Hosp Infect 2011;77:223-232.
6. Chaiyakunapruk N, Veenstra DL, Lipsky BA, Saint S. Chlorhexidine compared with povidone-iodine solution for vascular catheter-site care: a meta-analysis. Ann Intern Med 2002;136: 792-801.
7. O'Grady NP, Alexander M, Burns LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control 2011;39:S1-S34.
8. Chapman AK, Aucott SW, Milstone AM. Safety of chlorhexidine gluconate used for skin antisepsis in the preterm infant. J Perinatol 2012;32:4-9.
9. Garland JS, Alex CP, Mueller CD, Cisler-Kahill LA. Local reactions to a chlorhexidine gluconate-impregnated antimicrobial dressing in very low birth weight infants. Pediatr Infect Dis J 1996;15:912-914.
10. Reynolds PR, Banerjee S, Meek JH. Alcohol burns in extremely low birthweight infants: still occurring. Arch Dis Child Fetal Neonatal Ed 2005;90:F10.