Renal impairment after high-dose flucloxacillin and single-dose gentamicin prophylaxis in patients undergoing elective hip and knee replacement

Nephrology Dialysis Transplantation

Volumn 28, Issue 3, 2013, Pages 612-619

  Challagundla, Sudhakar Rao ^a   Knox, David ^a   Hawkins, Amanda ^a   Hamilton, David ^a   W v Flynn, Robert ^b   Robertson, Sue ^a   Isles, Chris ^a  

^a DUMFRIES AND GALLOWAY ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Acute kidney injury; Flucloxacillin; Gentamicin; Interstitial nephritis; Primary hip and knee arthroplasty

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CEFUROXIME; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EPHEDRINE; FLUCLOXACILLIN; GENTAMICIN; METARAMINOL; NONSTEROID ANTIINFLAMMATORY AGENT; TOBRAMYCIN;

ACUTE KIDNEY FAILURE; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; CLOSTRIDIUM DIFFICILE INFECTION; CONTROLLED STUDY; DRUG MEGADOSE; ELECTIVE SURGERY; FEMALE; HEMODIALYSIS; HIP ARTHROPLASTY; HUMAN; HUMAN TISSUE; HYPERTENSION; INCIDENCE; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KNEE ARTHROPLASTY; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PERIOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; SINGLE DRUG DOSE; TREATMENT RESPONSE;

ACUTE KIDNEY INJURY; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ANTIBIOTIC PROPHYLAXIS; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOXACILLIN; FOLLOW-UP STUDIES; GENTAMICINS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROGNOSIS; RETROSPECTIVE STUDIES; SURGICAL WOUND INFECTION;

EID: 84874835721     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfs458     Document Type: Article

References (17)

1. Pepin J, Valiquette P, Alary M-E et al. Clostridium difficile associated diarrhoea in a region of Quebec from 1991-2003: a changing pattern of disease severity. CMAJ 2004; 171: 466-472
2. Freeman J, Bauer MP, Baines SD et al. The changing epidemiology of Clostridium difficile infections. Clin Microbiol Rev 2010; 23: 529-549
3. Privitera G, Scarpellini P, Ortisi G et al. Prospective study of Clostridium difficile intestinal colonization and disease following single-dose antibiotic prophylaxis in surgery. Antimicrob Agents Chemother 1991; 35: 208-210
4. Antibiotic Prophylaxis in Surgery. A National Clinical Guideline. Scottish Intercollegiate Guidelines Network (SIGN) 104, July 2008. www.sign.ac.uk/guidelines (19 April 2012, date last accessed)
5. American Academy of Orthopaedic Surgeons. Information Statement: Recommendations for the Use of Intravenous Antibiotic Prophylaxis in Primary Total Joint Arthroplasty. http ://www.aaos.org/about/papers/advistmt/1027.asp (19 April 2012, date last accessed)
6. SAPG. Antibiotic prophylaxis in surgery. 2009. http://www. scottishmedicines.org.uk/files/Microsoft-Word-SAPG-Guidance-on-surgical- prophylaxis.pdf (29 February 2012, date last accessed)
7. Scottish Arthroplasty Project - Annual Report 2010. www.isdscotland.org/ isd/6457.html. (29 February 2012, date last accessed)
8. Solgaard L, Tuxoe JI, Mafi M et al. Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. Int Orthop 2000; 24: 155-157
9. Levey AS, Stevens LA, Schmid CH et al. A new equation to estimated glomerular filtration rate. Ann Intern Med 2009; 150: 604-612
10. Bellomo R, Ronco C, Kellum JA et al. on behalf of ADQI Work Group. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004; 8: R204-R212
11. Cochrane Effective Practice and Organisation of Care Review Group. The Data Collection Checklist. Ottawa: Cochrane Effective Practice and Organisation of Care Review Group, 2007
12. Rossert JA, Fischer EA. Acute interstitial nephritis. In: Feehally J, Floege J, Johnson RJ (eds). Comprehensive Clinical Nephrology, 3rd edn. Philadelphia: Mosby, 2007, pp. 681-689
13. Pusey CD, Saltissi D, Bloodworth L et al. Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy. Q J Med 1983; 52: 194-211
14. Spanou Z, Keller M, Britschgi M et al. Involvement of drugspecific T cells in acute drug-induced interstitialnephritis. J Am Soc Nephrol 2006; 17: 2919-2927
15. Xu B, Murray M. Flucloxacillin induced renal failure. Aust Fam Physician 2008; 37: 1009-1011
16. Wahlig H, Dingeldein E, Buchholz HW et al. Pharmacokinetic study of gentamicin-loaded cement in total hip replacements: comparative effects of varying dosage. J Bone Joint Surgery Br 1984; 66-B: 175-179
17. Jenkins PJ, Teoh K, Simpson PM et al. Clostridium difficile in patients undergoing primary hip and knee replacement. J Bone Joint Surg Br 2010; 92: 994-998