메뉴 건너뛰기




Volumn 18, Issue 1, 2013, Pages 155-163

A promising injectable scaffold: The biocompatibility and effect on osteogenic differentiation of mesenchymal stem cells

Author keywords

chitosan; hydrogel; mesenchymal stem cells; osteogenic differentiation; tissue engineering

Indexed keywords

ALKALINE PHOSPHATASE ACTIVITY; BONE TISSUE ENGINEERING; ECTOPIC BONE FORMATIONS; LASER CONFOCAL SCANNING MICROSCOPES; MESENCHYMAL STEM CELL; MORPHOLOGICAL OBSERVATIONS; OSTEOGENIC DIFFERENTIATION; REAL-TIME POLYMERASE CHAIN REACTION (REAL-TIME PCR);

EID: 84874829989     PISSN: 12268372     EISSN: 19763816     Source Type: Journal    
DOI: 10.1007/s12257-012-0429-z     Document Type: Article
Times cited : (23)

References (34)
  • 2
    • 49149096671 scopus 로고    scopus 로고
    • Biocompatibility and gelation of chitosan-glycerol phosphate hydrogels
    • Ahmadi, R. and J. D. de Bruijn (2008) Biocompatibility and gelation of chitosan-glycerol phosphate hydrogels. J. Biomed. Mater. Res. A 86: 824-832.
    • (2008) J. Biomed. Mater. Res. A , vol.86 , pp. 824-832
    • Ahmadi, R.1    De Bruijn, J.D.2
  • 3
    • 45549095243 scopus 로고    scopus 로고
    • Chitosan gel as an in situforming scaffold for rat bone marrow mesenchymal stem cells in vivo
    • 10.1089/ten.tea.2007.0305 1:CAS:528:DC%2BD1cXns1Oqsro%3D
    • Cho, M. H.; K. S. Kim, H. H. Ahn, M. S. Kim, S. H. Kim, G. Khang, B. Lee, and H. B. Lee (2008) Chitosan gel as an in situforming scaffold for rat bone marrow mesenchymal stem cells in vivo. Tissue Eng. Part A 14: 1099-1108.
    • (2008) Tissue Eng. Part A , vol.14 , pp. 1099-1108
    • Cho, M.H.1    Kim, K.S.2    Ahn, H.H.3    Kim, M.S.4    Kim, S.H.5    Khang, G.6    Lee, B.7    Lee, H.B.8
  • 4
    • 35348971546 scopus 로고    scopus 로고
    • Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels
    • 10.1016/j.biomaterials.2007.09.018 1:CAS:528:DC%2BD2sXht1Wqtb%2FO
    • Richardson, S. M.; N. Hughes, J. A. Hunt, A. J. Freemont, and J. A. Hoyland (2008) Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels. Biomaterials 29: 85-93.
    • (2008) Biomaterials , vol.29 , pp. 85-93
    • Richardson, S.M.1    Hughes, N.2    Hunt, J.A.3    Freemont, A.J.4    Hoyland, J.A.5
  • 5
    • 51049102115 scopus 로고    scopus 로고
    • The osteogenic differentiation of rat muscle-derived stem cells in vivo within in situ-forming chitosan scaffolds
    • 10.1016/j.biomaterials.2008.08.005 1:CAS:528:DC%2BD1cXhtVOrt7fE
    • Kim, K. S.; J. H. Lee, H. H. Ahn, J. Y. Lee, G. Khang, B. Lee, H. B. Lee, and M. S. Kim (2008) The osteogenic differentiation of rat muscle-derived stem cells in vivo within in situ-forming chitosan scaffolds. Biomaterials 29: 4420-4428.
    • (2008) Biomaterials , vol.29 , pp. 4420-4428
    • Kim, K.S.1    Lee, J.H.2    Ahn, H.H.3    Lee, J.Y.4    Khang, G.5    Lee, B.6    Lee, H.B.7    Kim, M.S.8
  • 6
    • 77649272267 scopus 로고    scopus 로고
    • Thermogelling chitosan and collagen composite hydrogels initiated with beta-glycerophosphate for bone tissue engineering
    • 10.1016/j.biomaterials.2010.01.131 1:CAS:528:DC%2BC3cXjtFKju7s%3D
    • Wang, L. and J. P. Stegemann (2010) Thermogelling chitosan and collagen composite hydrogels initiated with beta-glycerophosphate for bone tissue engineering. Biomaterials 31: 3976-3985.
    • (2010) Biomaterials , vol.31 , pp. 3976-3985
    • Wang, L.1    Stegemann, J.P.2
  • 7
    • 78349308986 scopus 로고    scopus 로고
    • Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels
    • 10.1007/s10856-010-4131-4 1:CAS:528:DC%2BC3cXhtlahs7vL
    • Song, K.; M. Qiao, T. Liu, B. Jiang, H. M. Macedo, X. Ma, and Z. Cui (2010) Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels. J. Mater. Sci. Mater. Med. 21: 2835-2842.
    • (2010) J. Mater. Sci. Mater. Med. , vol.21 , pp. 2835-2842
    • Song, K.1    Qiao, M.2    Liu, T.3    Jiang, B.4    Macedo, H.M.5    Ma, X.6    Cui, Z.7
  • 8
    • 80755133590 scopus 로고    scopus 로고
    • The osteogenic differentiation of dog bone marrow mesenchymal stem cells in a thermo-sensitive injectable chitosan/collagen/beta-glycerophosphate hydrogel: In vitro and in vivo
    • 10.1007/s10856-011-4386-4 1:CAS:528:DC%2BC3MXhtFWlsr%2FJ
    • Sun, B.; W. Ma, F. Su, Y. Wang, J. Liu, D. Wang, and H. Liu (2011) The osteogenic differentiation of dog bone marrow mesenchymal stem cells in a thermo-sensitive injectable chitosan/collagen/beta-glycerophosphate hydrogel: In vitro and in vivo. J. Mater. Sci. Mater. Med. 22: 2111-2118.
    • (2011) J. Mater. Sci. Mater. Med. , vol.22 , pp. 2111-2118
    • Sun, B.1    Ma, W.2    Su, F.3    Wang, Y.4    Liu, J.5    Wang, D.6    Liu, H.7
  • 9
    • 47749121495 scopus 로고    scopus 로고
    • Collagen scaffolds for tissue engineering
    • 10.1002/bip.20871 1:CAS:528:DC%2BD1cXksFWqs7o%3D
    • Glowacki, J. and S. Mizuno (2008) Collagen scaffolds for tissue engineering. Biopolymers 89: 338-344.
    • (2008) Biopolymers , vol.89 , pp. 338-344
    • Glowacki, J.1    Mizuno, S.2
  • 10
    • 79955009111 scopus 로고    scopus 로고
    • In vitro assessment of the differentiation potential of bone marrow-derived mesenchymal stem cells on genipin-chitosan conjugation scaffold with surface hydroxyapatite nanostructure for bone tissue engineering
    • 10.1089/ten.tea.2010.0497 1:CAS:528:DC%2BC3MXltVWquro%3D
    • Wang, G.; L. Zheng, H. Zhao, J. Miao, C. Sun, N. Ren, J. Wang, H. Liu, and X. Tao (2011) In vitro assessment of the differentiation potential of bone marrow-derived mesenchymal stem cells on genipin-chitosan conjugation scaffold with surface hydroxyapatite nanostructure for bone tissue engineering. Tissue Eng. Part A 17: 1341-1349.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 1341-1349
    • Wang, G.1    Zheng, L.2    Zhao, H.3    Miao, J.4    Sun, C.5    Ren, N.6    Wang, J.7    Liu, H.8    Tao, X.9
  • 11
    • 34247846240 scopus 로고    scopus 로고
    • Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/ polyamide composite scaffolds for bone tissue engineering
    • 10.1016/j.biomaterials.2007.04.014 1:CAS:528:DC%2BD2sXltFyntL8%3D
    • Wang, H.; Y. Li, Y. Zuo, J. Li, S. Ma, and L. Cheng (2007) Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering. Biomaterials 28: 3338-3348.
    • (2007) Biomaterials , vol.28 , pp. 3338-3348
    • Wang, H.1    Li, Y.2    Zuo, Y.3    Li, J.4    Ma, S.5    Cheng, L.6
  • 12
    • 82955182189 scopus 로고    scopus 로고
    • Synergistic effect of recombinant human bone morphogenic protein-7 and osteogenic differentiation medium on human bone-marrow-derived mesenchymal stem cells in vitro
    • 10.1007/s00264-011-1247-1
    • Zhi, L.; C. Chen, X. Pang, H. Uludag, and H. Jiang (2011) Synergistic effect of recombinant human bone morphogenic protein-7 and osteogenic differentiation medium on human bone-marrow-derived mesenchymal stem cells in vitro. Int. Orthop. 35: 1889-1895.
    • (2011) Int. Orthop. , vol.35 , pp. 1889-1895
    • Zhi, L.1    Chen, C.2    Pang, X.3    Uludag, H.4    Jiang, H.5
  • 13
    • 48349083016 scopus 로고    scopus 로고
    • PEG-stabilized carbodiimide crosslinked collagen-chitosan hydrogels for corneal tissue engineering
    • 10.1016/j.biomaterials.2008.06.017 1:CAS:528:DC%2BD1cXps1Srt7s%3D
    • Rafat, M.; F. Li, P. Fagerholm, N. S. Lagali, M. A. Watsky, R. Munger, T. Matsuura, and M. Griffith (2008) PEG-stabilized carbodiimide crosslinked collagen-chitosan hydrogels for corneal tissue engineering. Biomaterials 29: 3960-3972.
    • (2008) Biomaterials , vol.29 , pp. 3960-3972
    • Rafat, M.1    Li, F.2    Fagerholm, P.3    Lagali, N.S.4    Watsky, M.A.5    Munger, R.6    Matsuura, T.7    Griffith, M.8
  • 14
    • 33847026435 scopus 로고    scopus 로고
    • Biomaterials and scaffold design: Key to tissue-engineering cartilage
    • 10.1042/BA20060134 1:CAS:528:DC%2BD2sXitlSqurY%3D
    • Raghunath, J.; J. Rollo, K. M. Sales, P. E. Butler, and A. M. Seifalian (2007) Biomaterials and scaffold design: Key to tissue-engineering cartilage. Biotechnol. Appl. Biochem. 46: 73-84.
    • (2007) Biotechnol. Appl. Biochem. , vol.46 , pp. 73-84
    • Raghunath, J.1    Rollo, J.2    Sales, K.M.3    Butler, P.E.4    Seifalian, A.M.5
  • 15
    • 80455124097 scopus 로고    scopus 로고
    • Osteogenic differentiation and ectopic bone formation of canine bone marrowderived mesenchymal stem cells in injectable thermo-responsive polymer hydrogel
    • 10.1089/ten.tec.2011.0140 1:CAS:528:DC%2BC3MXhsVSit7fL
    • Liao, H. T.; C. T. Chen, and J. P. Chen (2011) Osteogenic differentiation and ectopic bone formation of canine bone marrowderived mesenchymal stem cells in injectable thermo-responsive polymer hydrogel. Tissue Eng. Part C Methods 17: 1139-1149.
    • (2011) Tissue Eng. Part C Methods , vol.17 , pp. 1139-1149
    • Liao, H.T.1    Chen, C.T.2    Chen, J.P.3
  • 16
    • 72149124487 scopus 로고    scopus 로고
    • Osteogenic differentiation of human amniotic fluid-derived stem cells induced by bone morphogenetic protein-7 and enhanced by nanofibrous scaffolds
    • 10.1016/j.biomaterials.2009.10.030 1:CAS:528:DC%2BD1MXhs1SltL7J
    • Sun, H.; K. Feng, J. Hu, S. Soker, A. Atala, and P. X. Ma (2010) Osteogenic differentiation of human amniotic fluid-derived stem cells induced by bone morphogenetic protein-7 and enhanced by nanofibrous scaffolds. Biomaterials 31: 1133-1139.
    • (2010) Biomaterials , vol.31 , pp. 1133-1139
    • Sun, H.1    Feng, K.2    Hu, J.3    Soker, S.4    Atala, A.5    Ma, P.X.6
  • 17
    • 78650891917 scopus 로고    scopus 로고
    • Osteogenic differentiation of human Wharton's jelly stem cells on nanofibrous substrates in vitro
    • 10.1089/ten.tea.2010.0224 1:CAS:528:DC%2BC3MXhvVCquw%3D%3D
    • Gauthaman, K.; J. R. Venugopal, F. C. Yee, A. Biswas, S. Ramakrishna, and A. Bongso (2011) Osteogenic differentiation of human Wharton's jelly stem cells on nanofibrous substrates in vitro. Tissue Eng. Part A 17: 71-81.
    • (2011) Tissue Eng. Part A , vol.17 , pp. 71-81
    • Gauthaman, K.1    Venugopal, J.R.2    Yee, F.C.3    Biswas, A.4    Ramakrishna, S.5    Bongso, A.6
  • 18
    • 36248989188 scopus 로고    scopus 로고
    • Chitosan and its derivatives for tissue engineering applications
    • 10.1016/j.biotechadv.2007.07.009 1:CAS:528:DC%2BD2sXhtlGnsrbF
    • Kim, I. Y.; S. J. Seo, H. S. Moon, M. K. Yoo, I. Y. Park, B. C. Kim, and C. S. Cho (2008) Chitosan and its derivatives for tissue engineering applications. Biotechnol. Adv. 26: 1-21.
    • (2008) Biotechnol. Adv. , vol.26 , pp. 1-21
    • Kim, I.Y.1    Seo, S.J.2    Moon, H.S.3    Yoo, M.K.4    Park, I.Y.5    Kim, B.C.6    Cho, C.S.7
  • 19
    • 0035811285 scopus 로고    scopus 로고
    • Synthesis and characterization of macroporous chitosan/calcium phosphate composite scaffolds for tissue engineering
    • 10.1002/1097-4636(20010605)55:3<304: AID-JBM1018>3.0.CO;2-J 1:CAS:528:DC%2BD3MXisVChtbs%3D
    • Zhang, Y. and M. Zhang (2001) Synthesis and characterization of macroporous chitosan/calcium phosphate composite scaffolds for tissue engineering. J. Biomed. Mater. Res. 55: 304-312.
    • (2001) J. Biomed. Mater. Res. , vol.55 , pp. 304-312
    • Zhang, Y.1    Zhang, M.2
  • 20
    • 0026744033 scopus 로고
    • Experimental study on osteoconductive properties of a chitosan-bonded hydroxyapatite self-hardening paste
    • 10.1016/0142-9612(92)90014-F 1:CAS:528:DyaK38XmsFyit7k%3D
    • Kawakami, T.; M. Antoh, H. Hasegawa, T. Yamagishi, M. Ito, and S. Eda (1992) Experimental study on osteoconductive properties of a chitosan-bonded hydroxyapatite self-hardening paste. Biomaterials 13: 759-763.
    • (1992) Biomaterials , vol.13 , pp. 759-763
    • Kawakami, T.1    Antoh, M.2    Hasegawa, H.3    Yamagishi, T.4    Ito, M.5    Eda, S.6
  • 21
    • 20444409137 scopus 로고    scopus 로고
    • Chitosan: A versatile biopolymer for orthopaedic tissue-engineering
    • 10.1016/j.biomaterials.2005.03.016
    • Di, M. A.; M. Sittinger, and M. V. Risbud (2005) Chitosan: A versatile biopolymer for orthopaedic tissue-engineering. Biomaterials 26: 5983-5990.
    • (2005) Biomaterials , vol.26 , pp. 5983-5990
    • Di, M.A.1    Sittinger, M.2    Risbud, M.V.3
  • 22
    • 51849153694 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein acts synergistically with beta-glycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells
    • 10.1002/jcb.21812 1:CAS:528:DC%2BD1cXhtFGns7zM
    • Bear, M.; M. Butcher, and S. G. Shaughnessy (2008) Oxidized low-density lipoprotein acts synergistically with beta-glycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells. J. Cell. Biochem. 105: 185-193.
    • (2008) J. Cell. Biochem. , vol.105 , pp. 185-193
    • Bear, M.1    Butcher, M.2    Shaughnessy, S.G.3
  • 24
    • 32344449299 scopus 로고    scopus 로고
    • Exogenous type i collagen facilitates osteogenic differentiation and acts as a substrate for mineralization of rat marrow mesenchymal stem cells in vitro
    • 10.1016/j.bbrc.2006.01.059 1:CAS:528:DC%2BD28Xhs1Wms7s%3D
    • Kihara, T.; M. Hirose, A. Oshima, and H. Ohgushi (2006) Exogenous type I collagen facilitates osteogenic differentiation and acts as a substrate for mineralization of rat marrow mesenchymal stem cells in vitro. Biochem. Biophys. Res. Commun. 341: 1029-1035.
    • (2006) Biochem. Biophys. Res. Commun. , vol.341 , pp. 1029-1035
    • Kihara, T.1    Hirose, M.2    Oshima, A.3    Ohgushi, H.4
  • 25
    • 79958700738 scopus 로고    scopus 로고
    • In vitro mineralization of human mesenchymal stem cells on threedimensional type i collagen versus PLGA scaffolds: A comparative analysis
    • 10.1097/PRS.0b013e318213a004 1:CAS:528:DC%2BC3MXmsF2lsL4%3D
    • Kruger, E. A.; D. D. Im, D. S. Bischoff, C. T. Pereira, W. Huang, G. H. Rudkin, D. T. Yamaguchi, and T. A. Miller (2011) In vitro mineralization of human mesenchymal stem cells on threedimensional type I collagen versus PLGA scaffolds: a comparative analysis. Plast. Reconstr. Surg. 127: 2301-2311.
    • (2011) Plast. Reconstr. Surg. , vol.127 , pp. 2301-2311
    • Kruger, E.A.1    Im, D.D.2    Bischoff, D.S.3    Pereira, C.T.4    Huang, W.5    Rudkin, G.H.6    Yamaguchi, D.T.7    Miller, T.A.8
  • 26
    • 80052475717 scopus 로고    scopus 로고
    • Osteogenic differentiation of human periosteal-derived cells in a three-dimensional collagen scaffold
    • 10.1007/s11033-010-9950-3 1:CAS:528:DC%2BC3MXlsVGjtbY%3D
    • Ryu, Y. M.; Y. S. Hah, B. W. Park, D. R. Kim, G. S. Roh, J. R. Kim, U. K. Kim, G. J. Rho, G. H. Maeng, and J. H. Byun (2011) Osteogenic differentiation of human periosteal-derived cells in a three-dimensional collagen scaffold. Mol. Biol. Rep. 38: 2887-2894.
    • (2011) Mol. Biol. Rep. , vol.38 , pp. 2887-2894
    • Ryu, Y.M.1    Hah, Y.S.2    Park, B.W.3    Kim, D.R.4    Roh, G.S.5    Kim, J.R.6    Kim, U.K.7    Rho, G.J.8    Maeng, G.H.9    Byun, J.H.10
  • 27
    • 77954765958 scopus 로고    scopus 로고
    • Type i collagen promotes proliferation and osteogenesis of human mesenchymal stem cells via activation of ERK and Akt pathways
    • Tsai, K. S.; S. Y. Kao, C. Y. Wang, Y. J. Wang, J. P. Wang, and S. C. Hung (2010) Type I collagen promotes proliferation and osteogenesis of human mesenchymal stem cells via activation of ERK and Akt pathways. J. Biomed. Mater. Res. A 94: 673-682.
    • (2010) J. Biomed. Mater. Res. A , vol.94 , pp. 673-682
    • Tsai, K.S.1    Kao, S.Y.2    Wang, C.Y.3    Wang, Y.J.4    Wang, J.P.5    Hung, S.C.6
  • 28
    • 80054060394 scopus 로고    scopus 로고
    • A novel tripolymer coating demonstrating the synergistic effect of chitosan, collagen type 1 and hyaluronic acid on osteogenic differentiation of human bone marrow derived mesenchymal stem cells
    • 10.1016/j.bbrc.2011.09.071 1:CAS:528:DC%2BC3MXhtlaksL7O
    • Mathews, S.; R. Bhonde, P. K. Gupta, and S. Totey (2011) A novel tripolymer coating demonstrating the synergistic effect of chitosan, collagen type 1 and hyaluronic acid on osteogenic differentiation of human bone marrow derived mesenchymal stem cells. Biochem. Biophys. Res. Commun. 414: 270-276.
    • (2011) Biochem. Biophys. Res. Commun. , vol.414 , pp. 270-276
    • Mathews, S.1    Bhonde, R.2    Gupta, P.K.3    Totey, S.4
  • 29
    • 0141534360 scopus 로고    scopus 로고
    • Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering
    • 10.1016/S0142-9612(03)00374-0 1:CAS:528:DC%2BD3sXnsF2qt7c%3D
    • Ma, L.; C. Gao, Z. Mao, J. Zhou, J. Shen, X. Hu, and C. Han (2003) Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering. Biomaterials 24: 4833-4841.
    • (2003) Biomaterials , vol.24 , pp. 4833-4841
    • Ma, L.1    Gao, C.2    Mao, Z.3    Zhou, J.4    Shen, J.5    Hu, X.6    Han, C.7
  • 31
    • 80053102721 scopus 로고    scopus 로고
    • The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials
    • 10.1016/j.biomaterials.2011.08.037 1:CAS:528:DC%2BC3MXht1WmtrfK
    • Hu, X.; S. H. Park, E. S. Gil, X. X. Xia, A. S. Weiss, and D. L. Kaplan (2011) The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials 32: 8979-8989.
    • (2011) Biomaterials , vol.32 , pp. 8979-8989
    • Hu, X.1    Park, S.H.2    Gil, E.S.3    Xia, X.X.4    Weiss, A.S.5    Kaplan, D.L.6
  • 32
    • 70849130059 scopus 로고    scopus 로고
    • Designing materials to direct stem-cell fate
    • 10.1038/nature08602 1:CAS:528:DC%2BD1MXhsVylsLnF
    • Lutolf, M. P.; P. M. Gilbert, and H. M. Blau (2009) Designing materials to direct stem-cell fate. Nature 462: 433-441.
    • (2009) Nature , vol.462 , pp. 433-441
    • Lutolf, M.P.1    Gilbert, P.M.2    Blau, H.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.