Safety and efficacy of drug-eluting bead chemoembolization for hepatocellular carcinoma: Comparison of small-versus medium-size particles

Journal of Vascular and Interventional Radiology

Volumn 24, Issue 3, 2013, Pages 301-306

  Padia, Siddharth A ^a   Shivaram, Giri ^a   Bastawrous, Sarah ^a   Bhargava, Puneet ^a   Vo, Nghia J ^a   Vaidya, Sandeep ^a   Valji, Karim ^a   Harris, William P ^a   Hippe, Daniel S ^a   Kogut, Matthew J ^a  

^a UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

complete response; CR; DEB; drug eluting bead; EASL; European Association for the Study of the Liver; HCC; hepatocellular carcinoma; partial response; PR; WHO; World Health Organization

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CEFAZOLIN; DOXORUBICIN; METRONIDAZOLE;

ABDOMINAL PAIN; ABSCESS; ADULT; AGED; ALOPECIA; ANTIBIOTIC PROPHYLAXIS; ARTICLE; ASCITES; BACTERIAL INFECTION; BILOMA; BRAIN DISEASE; CANCER PATIENT; CANCER REGRESSION; CANCER SIZE; CHEMOEMBOLIZATION; CHOLECYSTITIS; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG ELUTING BEAD; DRUG FATALITY; DRUG INDUCED DISEASE; DRUG RESPONSE; DRUG SAFETY; ERYTHEMA; FATIGUE; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; LEUKOCYTE; LIVER CELL CARCINOMA; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; PANCREATITIS; PARTICLE SIZE; PLEURA EFFUSION; POSTEMBOLIZATION SYNDROME; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SIDE EFFECT; THROMBOCYTE;

AGED; ANTIBIOTICS, ANTINEOPLASTIC; CARCINOMA, HEPATOCELLULAR; CHEMOEMBOLIZATION, THERAPEUTIC; CHI-SQUARE DISTRIBUTION; DOXORUBICIN; DRUG CARRIERS; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PARTICLE SIZE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 84874784518     PISSN: 10510443     EISSN: 15357732     Source Type: Journal    
DOI: 10.1016/j.jvir.2012.11.023     Document Type: Article

References (21)

1. G.L. Davis, M.J. Alter, H. El-Serag, T. Poynard, and L.W. Jennings Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progression Gastroenterology 138 2010 513 521
2. A.B. Benson, T.A. Abrams, and E. Ben-Josef NCCN clinical practice guidelines in oncology: hepatobiliary cancers J Natl Compr Canc Netw 7 2009 350 391
3. J. Lammer, K. Malagari, and T. Vogl Prospective randomized study of doxorubicin-eluting-bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study Cardiovasc Intervent Radiol 33 2010 41 52
4. R.C. Gaba Chemoembolization practice patterns and technical methods among interventional radiologists: results of an online survey AJR Am J Roentgenol 198 2012 692 699
5. K. Malagari, M. Pomoni, and A. Kelekis Prospective randomized comparison of chemoembolization with doxorubicin-eluting beads and bland embolization with BeadBlock for hepatocellular carcinoma Cardiovasc Intervent Radiol 33 2010 541 551
6. K. Malagari, M. Pomoni, and T.N. Spyridopoulos Safety profile of sequential transcatheter chemoembolization with DC Bead: results of 237 hepatocellular carcinoma (HCC) patients Cardiovasc Intervent Radiol 34 2011 774 785
7. R Lencioni, T de Baere, and M Burrel Transcatheter treatment of hepatocellular carcinoma with Doxorubicin-loaded DC Bead (DEBDOX): technical recommendations Cardiovasc Intervent Radiol 35 2012 980 985
8. R. Martin, J. Irurzun, and J. Munchart Optimal techniques and response of doxorubicin beads in hepatocellular cancer: bead size and dose Korean J Hepatol 17 2011 51 60
9. A. Trotti, A.D. Colevas, and A. Setser CTCAE v3.0: development of a comprehensive grading system for the adverse effects of cancer treatment Semin Radiat Oncol 13 2003 176 181
10. A.B. Miller, B. Hoogstraten, M. Staquet, and A. Winkler Reporting results of cancer treatment Cancer 47 1981 207 214
11. J. Bruix, M. Sherman, and J.M. Llovet Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver J Hepatol 35 2001 421 430
12. R. Sacco, I. Bargellini, and M. Bertini Conventional versus doxorubicin-eluting bead transarterial chemoembolization for hepatocellular carcinoma J Vasc Interv Radiol 22 2011 1545 1552
13. J. Kettenbach, A. Stadler, and IV Katzler Drug-loaded microspheres for the treatment of liver cancer: review of current results Cardiovasc Intervent Radiol 31 2008 468 476
14. T.M. Pawlik, D.K. Reyes, D. Cosgrove, I.R. Kamel, N. Bhagat, and J.F. Geschwind Phase II trial of sorafenib combined with concurrent transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma J Clin Oncol 29 2011 3960 3967
15. M.J. Song, C.H. Park, and J.D. Kim Drug-eluting bead loaded with doxorubicin versus conventional Lipiodol-based transarterial chemoembolization in the treatment of hepatocellular carcinoma: a case-control study of Asian patients Eur J Gastroenterol Hepatol 23 2011 521 527
16. K.H. Lee, E. Liapi, and J.A. Vossen Distribution of iron oxide-containing Embosphere particles after transcatheter arterial embolization in an animal model of liver cancer: evaluation with MR imaging and implication for therapy J Vasc Interv Radiol 19 2008 1490 1496
17. J. Namur, S.J. Citron, and M.T. Sellers Embolization of hepatocellular carcinoma with drug-eluting beads: doxorubicin tissue concentration and distribution in patient liver explants J Hepatol 55 2011 1332 1338
18. E.A. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) Eur J Cancer 45 2009 228 247
19. J.H. Shim, H.C. Lee, and S.O. Kim Which response criteria best help predict survival of patients with hepatocellular carcinoma following chemoembolization? A validation study of old and new models Radiology 262 2012 708 718
20. A. Riaz, F.H. Miller, and L.M. Kulik Imaging response in the primary index lesion and clinical outcomes following transarterial locoregional therapy for hepatocellular carcinoma JAMA 303 2010 1062 1069
21. K. Memon, L. Kulik, and R.J. Lewandowski Radiographic response to locoregional therapy in hepatocellular carcinoma predicts patient survival times Gastroenterology 141 2011 526 535