Optimization of spermatogenesis-regulating hormones in patients with non-obstructive azoospermia and its impact on sperm retrieval: A multicentre study

BJU International

Volumn 111, Issue 3 B, 2013, Pages

  Hussein, Alayman ^a   Ozgok, Yasar ^b   Ross, Lawrence ^c   Rao, Pravin ^c   Niederberger, Craig ^c  

^a MINIA UNIVERSITY   (Egypt)

^b GULHANE SCHOOL OF MEDICINE   (Turkey)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

clomiphene citrate; FSH; hCG; hMG; micro TESE; non obstructive azoospermia; testosterone

Indexed keywords

CHORIONIC GONADOTROPIN; CLOMIFENE CITRATE; FOLLITROPIN; HUMAN MENOPAUSAL GONADOTROPIN; LUTEINIZING HORMONE; TESTOSTERONE;

ADJUVANT THERAPY; ADULT; ARTICLE; AZOOSPERMIA; CONTROLLED STUDY; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEMEN ANALYSIS; SPERM RETRIEVAL; SPERMATOGENESIS; SPERMATOZOON DENSITY; TREATMENT OUTCOME;

ADULT; AZOOSPERMIA; CHORIONIC GONADOTROPIN; CLOMIPHENE; FOLLICLE STIMULATING HORMONE; HUMANS; LUTEINIZING HORMONE; MALE; MENOTROPINS; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERM RETRIEVAL; SPERMATOGENESIS; TESTOSTERONE;

EID: 84874754541     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2012.11485.x     Document Type: Article

References (16)

1. Finkel DM, Phillips JL, Snyder PJ,. Stimulation of spermatogenesis by gonadotropins in men with hypogonadotropic hypogonadism. N Engl J Med 1985; 313: 651-5
2. Aydos K, Unlü C, Demirel LC, Evirgen O, Tolunay O,. The effect of pure FSH administration in non-obstructive azoospermic men on testicular sperm retrieval. Eur J Obstet Gynecol Reprod Biol 2003; 108: 54-8
3. Safeer Z, Zulfiqar S, Khan S,. Evaluation of effects of clomiphene citrate on serum testosterone & FSH levels and seminal parameters in idiopathic oligospermia. Biomedica 2009; 25: 48-5
4. Sigman M, Jonathan P,. Jarow: Male Infertility. In, Walsh PC, Retik AB, Vaughan ED, Wein AJ, eds, Campbell's Urology, 8th edn. Philadelphia: Saunders Co., 2003; 43: 1475-531
5. Jarow JP, Zirkin BR,. The androgen microenvironment of the human testis and hormonal control of spermatogenesis. Ann N Y Acad Sci 2005; 1061: 208-20
6. McLachlan RI, Wreford NG, O'Donnell L, De Kretser DM, Robertson DM,. The endocrine regulation of spermatogenesis: independent roles for testosterone and FSH. J Endocrinol 1996; 148: 1-9
7. Hussein A, Ozgok Y, Ross L, Niederberger C,. Clomiphene administration for cases of nonobstructive azoospermia: a multicenter study. J Androl 2005; 26: 787-91
8. Burris AS, Rodbard HW, Winters SJ, Sherins RJ,. Gonadotropin therapy in men with isolated hypogonadotropic hypogonadism: the response to human chorionic gonadotropin is predicted by initial testicular size. J Clin Endocrinol Metab 1988; 66: 1144-51
9. Schill WB, Jungst D, Unterburger P, Braun S,. Combined hMG/hCG treatment in subfertile men with idiopathic normogonadotrophic oligozoospermia. Int J Androl 1982; 5: 467-77
10. Miyagawa Y, Tsujimura A, Matsumiya K, et al,. Outcome of gonadotropin therapy for male hypogonadotropic hypogonadism at university affiliated male infertility centers: a 30-year retrospective study. J Urol 2005; 173: 2072-5
11. Pasqualotto FF, Fonseca GP, Pasqualotto EB,. Azoospermia after treatment with clomiphene citrate in patients with oligospermia. Fertil Steril 2008; 90: 2014-1
12. Dohle GR, Elzanaty S, Van Casteren NJ,. Testicular biopsy: clinical practice and interpretation. Asian J Androl 2012; 14: 88-93
13. Amer M, Ateyah A, Hany R, Zohdy W,. Prospective comparative study between microsurgical and conventional testicular sperm extraction in non-obstructive azoospermia: follow-up by serial ultrasound examinations. Hum Reprod 2000; 15: 653-6
14. Ghalayini IF, Al-Ghazo MA, Hani OB, et al,. Clinical comparison of conventional testicular sperm extraction and microdissection techniques for non-obstructive azoospermia. J Clin Med 2011; 3: 124-31
15. Okada H, Dobashi M, Yamazaki T, et al,. Conventional versus microdissection testicular sperm extraction for nonobstructive azoospermia. J Urol 2002; 168: 1063-7
16. Ramasamy R, Yagan N, Schlegel PN,. Structural and functional changes to the testis after conventional versus microdissection testicular sperm extraction. Urology 2005; 65: 1190-4