Optimization and production of prodigiosin from Serratia marcescens MBB05 using various natural substrates

Asian Journal of Pharmaceutical and Clinical Research

Volumn 6, Issue 1, 2013, Pages 34-41

  Pradeep, Bhathini Vaikuntavasan ^a   Pradeep, Francis Stanly ^a   Angayarkanni, Jayaraman ^b   Palaniswamy, Muthusamy ^a  

^a KARPAGAM UNIVERSITY   (India)

^b BHARATHIAR UNIVERSITY   (India)

Author keywords

Natural substrate; Peanut powder; Prodigiosin; Serratia marcescens

Indexed keywords

PRODIGIOSIN; RNA 16S;

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATION; CARBON SOURCE; CONTROLLED STUDY; DRUG SYNTHESIS; INCUBATION TIME; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; PHYSICAL CHEMISTRY; PROCESS OPTIMIZATION; RNA SEQUENCE; SEQUENCE ALIGNMENT; SERRATIA MARCESCENS; TEMPERATURE;

EID: 84874749801     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Williamson NR, Simonsen HT, Harris AKP, Leeper F, Salmond GPC. Disruption of the copper efflux pump (CopA) of Serratia marcescens ATCC 274 pleiotropically affects copper sensitivity and production of the tripyrrole secondary metabolite, prodigiosin. J Ind Microbiol Biotechnol 2006b; 33:151-158.
2. Sole M, Francia A, Rius N, Loren JG. The role of pH in the glucose effect on prodigiosin production by non-proliferating cells of Serratia marcescens. Lett Appl Microbiol 1997; 25: 81-84.
3. Williams RP, Green JA, Rappoport DA. Studies on pigmentation of Serratia marcescens I. Spectral and paper chromatographic properties of prodigiosin. J Bacteriol 1956b; 71:115-120.
4. Williamson NR, Fineran PC, Leeper FJ, Salmond GPC. The biosynthesis and regulation of bacterial prodiginines. Nature Rev Microbiol 2006a; 4: 887-899.
5. D'Alessio RA, Bargiotti, Carlin O, Colotta F, Ferrari M, Gnocchi P, Isetta A, Mongelli N, Motta P, Rossi A, Tibolla M, Vanotti E. Synthesis and immunosuppressive activity of novel prodigiosin derivatives. J Med Chem 2000; 43: 2557-2565.
6. Deorukhkar AA, Chander R, Ghosh SK, Sainis KB. Identification of a red-pigmented bacterium producing a potent anti-tumor N-alkylated prodigiosin as Serratia marcescens. Res Microbiol 2007; 58: 399-404.
7. Azambuja P, Feder D, Garcia ES. Isolation of Serratia marcescens in the midgut of Rhodnius prolixus: impact on the establishment of the parasite Trypanosoma cruzi in the vector. Exp Parasitol 2004; 107: 89-96.
8. Gerber NN. Prodigiosin-like pigments. Crit Rev Microbiol 1975; 3: 469-485.
9. Williams RP, Qadri SMH. The pigment of Serratia. In The Genus Serratia ed. Boca Raton, FL: CRC Press; 1980. p. 31-78.
10. Bennett JW, Bentley R. Seeing red: The story of prodigiosin. Advan Appl Microbiol 2000; 47: 1-32.
11. Sathya R, Pradeep BV, Angayarkanni J, Palaniswamy M. Production of milk clotting protease by a local isolate of Mucor circinelloides under SSF using agro-industrial wastes. Biotechnol Bioprocess Eng 2009; 14: 788-794.
12. Cang S, Sanada M, Johdo O, Ohta S, Nagamatsu Y, Yoshimoto A. High production of prodigiosin by Serratia marcescens grown on ethanol. Biotechnol Lett 2000; 22: 1761-1765.
13. Cook AE, Meyers PR. Rapid identification of filamentous actinomycetes to the genus level using genus-specific 16S rRNA gene restriction fragment patterns. Int J Syst Evol Microbiol 2003; 53: 1907-1915.
14. Coombs JT, Franco CM. Isolation and identification of actinobacteria isolated from surface-sterilized wheat roots. Appl Environ Microbiol 2003; 69: 5303-5308.
15. Weisburg WG, Barns SM, Pelletier DA, Lane DJ. 16S ribosomal DNA amplification for phylogenetic study. J Bacteriol 1991; 173: 697-703.
16. Gargallo-Viola D. Enzyme polymorphism, prodigiosin production, and plasmid fingerprints in clinical and naturally occurring isolates of Serratia marcescens. J Clin Microbiol 1989; 27: 860-868.
17. Ajithkumar B, Ajithkumar VP, Iriye R, Doi Y, Sakai T. Spore-forming Serratia marcescens subsp. sakuensis subsp. nov., isolated from a domestic wastewater treatment tank. Int J Syst Evol Microbiol 2003; 53: 253-258.
18. Deorukhkar AA, Chander R, Ghosh SK, Sainis KB. Identification of a red-pigmented bacterium producing a potent anti-tumor N-alkylated prodigiosin as Serratia marcescens. Res Microbiol 2007; 58: 399-404.
19. Anuradha VG, Nandini A, Geetha M, Gautam P. A novel medium for the enhanced cell growth and production of prodigiosin from Serratia marcescens isolated from soil. BMC Microbiol 2004; 4: 1-11.
20. Pryce LH, Terry FW. Spectrophotometric assay of gene expression: Serratia marcescens Pigmentation. Bioscen 2000; 26: 3-13.
21. Williams RP, Goldschmidt ME, Gott CL. Inhibition by temperature of the terminal step in biosynthesis of prodigiosin. Biochem Biophys Res Commun 1965; 19: 177-181.
22. Williams RP, Gott CL, Qadri SMH, Scott RH. Influence of temperature of incubation and type of growth medium on pigmentation in Serratia marcescens. J Bacteriol 1971b; 106: 438-443.
23. Haavik HI. Studies on the formation of bacitracin by Bacillus licheniformis: role of catabolite repression and organic aids. J Gen Microbiol 1974; 84: 321-326.
24. Chang SC, Wei YH, Wei DL, Chen YY, Jong SC. Factors affecting the production of eremofortin C and PR toxin in Penicillium roqueforti. Appl Environ Microbiol 1991; 57: 2581-2585.
25. James PDA, Edwards C, Dawson M. The effects of temperature, pH and growth rate on secondary metabolism in Streptomyces thermoviolaceus grown in a chemostat. J Gen Microbiol 1991; 137: 1715-1720.
26. Shah AJ, Tinhorns V, Aldard MW, Arst HN. pH regulation of penicillin production in Aspergillus nidulans. FEMS Microbiol Lett 1991; 77: 209-212.
27. Sole M, Rius N, Francia A, Loren JG. The effect of pH on prodigiosin production by non-proliferating cells of Serratia marcescens. Lett Appl Microbiol 1994; 19: 341-344.
28. Woods R, Mosmann TR, Hanson S, Hendry DA. Pigmentatoin and Acriflavin resistance in Serratia marcescens. J Bacteriol 1971; 108: 765-769.
29. Ruis N, Sole, Francia M, Loren AJG. Buffering capacity of pigmented and non-pigmented strains of Serratia marcescens. Appl Environ Microbiol 1994; 60: 2152-2154.
30. Williams RP, Qadri SMH. The pigment of Serratia. In The Genus Serratia ed. Boca Raton, FL: CRC Press; 1980. p. 31-78.
31. Jonas D, Schultheis B, Klas C, Krammer PH, Bhakdi S. Cytocidal effects of Escherichia coli hemolysin on human T lymphocytes. Infect Immunol 1993; 61: 1715-1721.
32. Tao JL, Wang XD, Shen YL, Wei DZ. Strategy for the improvement of prodigiosin production by a Serratia marcescens mutant through fed-batch fermentation. World J Microbiol Biotechnol 2005; 21: 969-972.
33. Yuan Z, Cang S, Matsufuji M, Nakata K, Nagamatsu Y, Yoshimoto A. High production of pyoluteorin and 2, 4-diacetylphloroglucinol by Pseudomonas fluorescens 272 grown ethanol as a sole carbon source. J Ferment Bioeng 1998; 86: 559-563.
34. Gallo M, Katz E. Regulation of secondary metabolite biosynthesis: catabolite repression of phenoxazinone synthase and actinomycin formation by glucose. J Bacteriol 1972; 109: 659-667.
35. Martin JF, Demain AL. Control of antibiotic biosynthesis. Microbiol Rev 1980; 44: 230-251.
36. Loren JG, Guinea J. Effect of glucose concentration on the biosynthesis of prodigiosin by Serratia marcescens. Evista Espanola de Fisiologia 1978; 34: 247-252.
37. Pastan I, Adhya S. Cyclic adenosine 5'-monophosphate in Escherichia coli. Bacteriol Rev 1976; 40: 527-551.
38. Tanaka WK, deMedina LB, Hearn WR. Labeling patterns in prodigiosin biosynthesis. Biochem Biophys Res Commun 1972; 46: 731-737.
39. Bostford JL. Cyclic nucleotides in prokaryotes. Microbiol Rev 1981; 45: 620-642.
40. Haavik HI. Studies on the formation of bacitracin by Bacillus licheniformis: role of catabolite repression and organic aids. J Gen Microbiol 1974; 84: 321-326.
41. Ragan CM, Vining C. Intracellular cyclic adenosine 3', 5' monophosphate levels and streptomycin production in cultures of Streptomyces griseus. Can J Microbiol 1978; 24: 1012-1015.
42. Chatterjee S, Vining LC. Catabolite repression in Streptomyces venezuelae. Induction of betagalactosidase, chloramphenicol production and intracellular cyclic adenosine 3', 5' monophosphate. Can J Microbiol 1982; 28: 311-317.
43. Kragelund L, Christrofferson B, Nybore O, de Bruijin FT. Isolation of lux gene fusion in Pseudomonas fluorescens DF57 inducible by starvation for nitrogen or phosphorus. FEMS Microbiol Ecol 1995; 17: 95-106.
44. Scott RH, Qadri SMH, Williams RP. Role of L-Proline in the biosynthesis of prodigiosin. Appl Environ Microbiol 1976; 32: 561-565.
45. Williams RP, Scott RH, Lim DV, Qadri SMH. Macromolecular synthesis during biosynthesis of prodigiosin by Serratia marcescens. Appl Environ Microbiol 1976; 31: 70-77.
46. Williams RP, Gott CL, Qadri SMH. Induction of pigmentation in nonproliferating cells of Serratia marcescens by addition of single amino acids. J Bacteriol 1971a; 106: 444-448.
47. Tanaka WK, deMedina LB, Hearn WR. Labeling patterns in prodigiosin biosynthesis. Biochem Biophys Res Commun 1972; 46: 731-737.
48. Wasserman HH, Sykes RJ, Peverada PP, Shaw CK, Cushley RJ, Lipsky SR. Biosynthesis of prodigiosin Incorporation patterns of '3C-labeled alanine, proline, glycine, and serine elucidated by Fourier transform nuclear magnetic resonance. J Am Chem Soc 1973; 95: 6874-6875.
49. Kim CH, Sung-Ho K, Suk-In. Isolation and Characteristics of prodigiosin like red pigment produced by Serratia sp. KH-95. Kor J Appl Microbiol Biotechnol 1998; 26(4):283-289.
50. Nakamura.1981; US Patent No: 4, 266, 028.
51. Khanafari A, Assadi MM, Fakh FA. Review of prodigiosin, pigmentation in Serratia marcescens. Online J Biologic Sci 2006; 6: 1-13.