The long-term regulation of food intake and body weight depends on the availability of thyroid hormones in the brain

Neuroendocrinology Letters

Volumn 33, Issue 7, 2012, Pages 703-708

  Alva Sánchez, Claudia ^a   Pacheco Rosado, Jorge ^a   Fregoso Aguilar, Tomás ^a   Villanueva, Iván ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

Body weight regulation; Feeding behavior; Food intake; Long term; Methimazole; Pharmacological hypothyroidism; PTU; Thyroid hormones; Thyroxine

Indexed keywords

LIOTHYRONINE; THYROID HORMONE; THYROXINE;

ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; BODY WEIGHT; BRAIN; ENERGY BALANCE; ENERGY EXPENDITURE; FEEDING BEHAVIOR; FLUID INTAKE; FOOD INTAKE; HYPOTHYROIDISM; LIOTHYRONINE BLOOD LEVEL; NONHUMAN; RAT; THYROXINE BLOOD LEVEL;

EID: 84874746910     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Aschoff J, Günther B, Kramer K (1971). Energiehaushalt und temperaturregulation. Munich: Urban & Schwarzenberg.
2. Bates JM, St Germain DL, Galton VA (1999). Expression profiles of the three iodothyronine deiodinases, D1, D2, and D3, in the developing rat. Endocrinology. 140: 844-851. (Pubitemid 29058221)
3. Bernal J (2005). The significance of thyroid hormone transporters in the brain. Endocrinology. 146: 1698-1700.
4. Bianco AC, Salvatore D, Gereben, B, Berry MJ, Larsen PR (2002). Biochemistry, cellular and molecular biology, and physiologycal roles of the iodothyronine selenodeiodinases. Endoc Rev. 23: 38-89. (Pubitemid 34185306)
5. Cabanac M (2001). Regulation and the ponderostat. Int J Obes Relat Metab Disord. 25 Suppl 5: S7-S12.
6. Crantz FR, Silva JE, Larsen PR (1982). An analysis of the sources and quantity of 3,5,3′-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology. 110: 367-375. (Pubitemid 12162924)
7. De Pergola G, Ciampolillo A, Paolotti S, Trerotoli P, Giorgino R (2007). Free triiodothyronine and thyroid stimulating hormone are directly associated with waist circumference, independently of insulin resistance, metabolic parameters and blood pressure in overweight and obese women. Clin Endocrinol (Oxf). 67: 265-269. (Pubitemid 47076304)
8. Escobar-Morreale HF, del Rey FE, Obregón MJ, de Escobar GM (1996). Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat. Endocrinology. 137: 2490-2502. (Pubitemid 26155786)
9. Gereben B, Zeöld A, Dentice M, Salvatore D, Bianco AC (2008). Activation and inactivation of thyroid hormone by deiodinases: Local action with general consequences. Cell Mol Life Sci. 65: 570-590.
10. Gurney C, Hall R, Harper M, Owen SG, Roth M, Smart GA (1970). Newcastle thyrotoxicosis index. Lancet. 2: 1275-1278.
11. Hagen GA, Solberg LA Jr (1974). Brain and cerebrospinal fluid permeability to intravenous thyroid hormones. Endocrinology. 95: 1398-1410.
12. Hsieh CJ, Wang PW, Wang ST, Liu RT, Tung SC, Chien WY, et al (2002). Serum leptin concentrations of patients with sequential thyroid function changes. Clin Endocrinol (Oxf). 57: 29-34.
13. Kong WM, Martin NM, Smith KL, Gardiner JV, Connoley IP, Stephens DA, et al (2004). Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure. Endocrinology. 145: 5252-5258. (Pubitemid 39551147)
14. Levin BE, Keesey RE (1998). Defense of differing body weight set points in diet-induced obese and resistant rats. Am J Physiol. 274: R412-R419.
15. López M, Varela L, Vázquez MJ, Rodríguez-Cuenca S, González CR, Velagapudi VR, et al (2010). Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med. 16: 1001-1008.
16. Luo L, MacLean DB (2003). Effects of thyroid hormone on food intake, hypothalamic Na/K ATPase activity and ATP content. Brain Res. 973: 233-239. (Pubitemid 36549161)
17. Matsumura M, Kuzuya N, Kawakami Y, Yamashita K (1992). Effects of fasting, refeeding, and fasting with T3 administration on Na-K, ATPase in rat skeletal muscle. Metabolism. 41: 995-999.
18. Oge A, Bayraktar F, Saygili F, Guney E, Demir S (2005). TSH influences serum leptin levels independent of thyroid hormones in hypothyroid and hyperthyroid patients. Endocr J. 52: 213-217. (Pubitemid 40745709)
19. O'Mara BA, Dittrich W, Lauterio TJ, St Germain DL (1993). Pretranslational regulation of type I 5′-deiodinase by thyroid hormones and in fasted and diabetic rats. Endocrinology. 133: 1715-1723. (Pubitemid 23295200)
20. Pinkney JH, Goodrick SJ, Katz J, Johnson AB, Lightman SL, Coppack SW, et al (1998). Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. Clin Endocrinol (Oxf). 49: 583-588. (Pubitemid 28529755)
21. Reinehr T, Andler W (2002). Thyroid hormones before and after weight loss in obesity. Arch Dis Child. 87: 320-323.
22. Roy G, Mugesh G (2006). Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. Bioinorg Chem Appl 2006: 23214.
23. Sharlin DS, Gilbert ME, Taylor MA, Ferguson DC, Zoeller RT (2010). The nature of the compensatory response to low thyroid hormone in the developing brain. J Neuroendocrinol. 22: 153-165.
24. Silva JE, Leonard JL, Crantz FR, Larsen PR (1982). Evidence for two tissue-specific pathways for in vivo thyroxine 5′-deiodination in the rat. J Clin Invest. 69: 1176-1184. (Pubitemid 12115682)
25. Westerterp KR, Speakman JR (2008). Physical activity energy expenditure has not declined since the 1980s and matches energy expenditures of wild mammals. Int J Obes (Lond). 32: 1256-1263.
26. Ying H, Araki O, Furuya F, Kato Y, Cheng SY (2007). Impaired adipogenesis caused by a mutated thyroid hormone alpha 1 receptor. Mol Cell Biol. 27: 2359-2371. (Pubitemid 46418487)