Advances in targeting signal transduction pathways

Oncotarget

Volumn 3, Issue 12, 2012, Pages 1505-1521

  McCubrey, James A ^a   Steelman, Linda S ^a   Chappel, William H ^a   Lin Sun, ^a,b   Davis, Nicole M ^a   Abrams, Stephen L ^a   Franklin, Richard A ^a   Cocco, Lucio ^c   Evangelisti, Camilla ^d   Chiarini, Francesca ^d   Martelli, Alberto M ^c,d   Libra, Massimo ^a   Candido, Saverio ^e   Ligresti, Giovanni ^e   Malaponte, Grazia ^e   Mazzarino, Maria C ^e   Fagone, Paolo ^e   Donia, Marco ^e   Nicoletti, Ferdinando ^e   Polesel, Jerry ^f   Talamini, Renato ^f   Bäsecke, Jörg ^g   Mijatovic, Sanja ^h   Maksimovic Ivanic, Danijela ^h   Milella, Michele ⁱ   Tafuri, Agostino ^j   Dulińska Litewka, Joanna ^k   Laidler, Piotr ^k   D'Assoro, Antonio B ^l   Drobot, Lyudmyla ^m   Umezawa, Kazuo ⁿ   Montalto, Giuseppe ^o   Cervello, Melchiorre ^d   Demidenko, Zoya N ^p   more..

^a EAST CAROLINA UNIVERSITY   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d CNR   (Italy)

^e UNIVERSITY OF CATANIA   (Italy)

^f CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^g UNIVERSITY OF GÖTTINGEN   (Germany)

^h UNIVERSITY OF BELGRADE   (Serbia)

ⁱ REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^j SAPIENZA UNIVERSITY OF ROME   (Italy)

^k JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^l MAYO GRADUATE SCHOOL   (United States)

^m PALLADIN INSTITUTE OF BIOCHEMISTRY   (Ukraine)

ⁿ AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^o UNIVERSITY OF PALERMO   (Italy)

^p ROSWELL PARK CANCER INSTITUTE   (United States)

more..

Author keywords

Akt; AMPK; Cancer stem cells; Metformin; MTOR; PI3K; Raf; Targeted therapy; Therapy resistance

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; 4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; ANTINEOPLASTIC AGENT; B RAF KINASE; B RAF KINASE INHIBITOR; CHLOROQUINE; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; GEFITINIB; HYDROXYCHLOROQUINE; K RAS PROTEIN; LIM KINASE 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; NEUROFIBROMIN; P21 ACTIVATED KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN; SALIRASIB; SORAFENIB; UNINDEXED DRUG; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; BRAF GENE; BRAIN TUMOR; CANCER COMBINATION CHEMOTHERAPY; CARCINOGENESIS; CHEMOSENSITIVITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE MUTATION; HUMAN; KRAS GENE; LIVER CELL CARCINOMA; MALIGNANT NEOPLASTIC DISEASE; MELANOMA; NONHUMAN; PLEIOTROPY; PREDICTION; PROSTATE CANCER; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

EID: 84874737273     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.802     Document Type: Review

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