Effect of mebudipine on oxidative stress and lipid peroxidation in myocardial ischemic-reperfusion injury in male rat

Journal of Research in Medical Sciences

Volumn 17, Issue 12, 2012, Pages 1150-1155

  Ghyasi, Rafigheh ^a   Sepehri, Gholamreza ^b   Mohammadi, Mustafa ^a   Badalzadeh, Reza ^a   Ghyasi, Akbar ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Ischemia; Lipid peroxidation; Mebudipine; Myocardial; Oxidative stress; Reperfusion

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MEBUDIPINE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; HEART PROTECTION; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; REPERFUSION INJURY;

EID: 84874697193     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. BaroldiG. Letter: Myocardial necrosis: the need for definition. J Mol Cell Cardiol 1974;6:401-2.
2. BoudinaS, LaclauMN, TariosseL, DaretD, GouverneurG, Bonoron-Adele S, et al. Alteration of mitochondrial function in a model of chronic ischemia in vivo in rat heart. Am J Physiol Heart Circ Physiol 2002;282:H821-31.
3. RastaldoR, PagliaroP, CappelloS, PennaC, MancardiD, Westerhof N, et al. Nitric oxide and cardiac function. Life Sci 2007;81:779-93.
4. GrossGJ, AuchampachJA. Reperfusion injury: Does it exist? J Mol Cell Cardiol 2007;42:12-8.
5. PandaVS, NaikSR. Cardioprotective activity of Ginkgo biloba Phytosomes in isoproterenol-induced myocardial necrosis in rats: Abiochemical and histoarchitectural evaluation. Exp Toxicol Pathol 2008;60:397-404.
6. MoensAL, ClaeysMJ, TimmermansJP, VrintsCJ. Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process. Int J Cardiol 2005;100:179-90.
7. GhyasiR, MohammadiM, BadalzadehR, RashidiB, SepehriG. The effect of mebudipine on cardiac function and activity of the myocardial nitric oxide system in ischaemia-reperfusion injury in rats. Cardiovasc J Afr 2011;22:319-23.
8. KatsumataN, MaX, HiguchiH. Protective effect of diltiazem against ischemia-induced decreases in regional myocardial flow in rat heart. Eur J Pharmacol 2000;398:83-91.
9. RousseauG, ProvostP, TranD, CailleG, LatourJG. Clentiazem given at reperfusion improves subendocardial reflow and reduces myocardial infarct size in the dog. JPharmacol Exp Ther 1994;268:1252-60.
10. TamuraK, SuzukiY, KogaT, AkimaM, KatoT, NabataH. Actions of CP-060S on veratridine-induced Ca2+ overload in cardiomyocytes and mechanical activities in vascular strips. Eur J Pharmacol 1996;312:195-202.
11. Ver DonckL, Van ReemptsJ, VandeplasscheG, BorgersM. Anew method to study activated oxygen species induced damage in cardiomyocytes and protection by Ca2+-antagonists. JMol Cell Cardiol 1988;20:811-23.
12. GodfraindT. Antioxidant effects and the therapeutic mode of action of calcium channel blockers in hypertension and atherosclerosis. Philos Trans R Soc Lond B Biol Sci 2005;360:2259-72.
13. MirkhaniH, DirinM, Youssef-ZayehI. Mechanism of vasoselective action of mebudipine, a new calcium channel blocker. Vascul Pharmacol 2004;42:23-9.
14. RouzrokhA, EbrahimiSA, Rahbr-RoshandelN, MahmoudianM. Effects of mebudipine and dibudipine, two new calcium channel blockers on voltage-activated calcium currents of PC12cells. Acta Physiol Hung 2007;94:199-207.
15. BeckerBF, MobertJ. Low-dose calcium antagonists reduce energy demand and cellular damage of isolated hearts during both ischemia and reperfusion. Naunyn Schmiedebergs Arch Pharmacol 1999;360:287-94.
16. MassoudyP, BeckerBF, SeligmannC, GerlachE. Preischaemic as well as postischaemic application of a calcium antagonist affords cardioprotection in the isolated guinea pig heart. Cardiovasc Res 1995;29:577-82.
17. Vander HeideRS, SchwartzLM, ReimerKA. The novel calcium antagonist Ro 40-5967 limits myocardial infarct size in the dog. Cardiovasc Res 1994;28:1526-32.
18. RothermelB, VegaRB, YangJ, WuH, Bassel-DubyR, WilliamsRS. A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling. J Biol Chem 2000;275:8719-25.
19. SiuPM, WangY, AlwaySE. Apoptotic signaling induced by H2O2-mediated oxidative stress in differentiated C2C12 myotubes. Life Sci 2009;84:468-81.
20. Delmas-BeauvieuxMC, PeuchantE, DumonMF, ReceveurMC, LeBrasM, ClercM. Relationship between red blood cell antioxidant enzymatic system status and lipoperoxidation during the acute phase of malaria. Clin Biochem 1995;28:163-9.
21. PagliaDE, ValentineWN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-69.
22. Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6.
23. DrogeW. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
24. Hamilton KL. Antioxidants and cardioprotection. Med Sci Sports Exerc 2007;39:1544-53.
25. NecasJ, BartosikovaL, FlorianT, KlusakovaJ, SuchyV, NaggarEM, et al. Protective effects of the flavonoids osajin and pomiferin on heart ischemia-reperfusion. Ceska Slov Farm 2006;55:168-74.
26. AllanoreY, BorderieD, PerianinA, LemarechalH, EkindjianOG, Kahan A. Nifedipine protects against overproduction of superoxide anion by monocytes from patients with systemic sclerosis. Arthritis Res Ther 2005;7:R93-100.
27. Noronha-DutraAA, Steen-DutraEM, WoolfN. An antioxidant role for calcium antagonists in the prevention of adrenaline mediated myocardial and endothelial damage. Br Heart J 1991;65:322-5.