Use of the modified Atkins diet for treatment of refractory childhood epilepsy: A randomized controlled trial

Epilepsia

Volumn 54, Issue 3, 2013, Pages 481-486

  Sharma, Suvasini ^a,b   Sankhyan, Naveen ^a,c   Gulati, Sheffali ^a   Agarwala, Anuja ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b KALAWATI SARAN CHILDREN'S HOSPITAL   (India)

^c POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Dietary therapies; Epilepsy surgery; Ketogenic diet

Indexed keywords

ADOLESCENT; ADVERSE OUTCOME; ANOREXIA; ARTICLE; ATKINS DIET; BENIGN CHILDHOOD EPILEPSY; BRAIN DISEASE; CHEST INFECTION; CHILD; CONSTIPATION; CONTROLLED STUDY; DIET; EPILEPSY; FEMALE; FOLLOW UP; HUMAN; INTENTION TO TREAT ANALYSIS; LETHARGY; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; OPEN STUDY; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; VOMITING;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; DIET, CARBOHYDRATE-RESTRICTED; EPILEPSY, ABSENCE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; TREATMENT OUTCOME;

EID: 84874683747     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12069     Document Type: Article

References (18)

1. Ballaban-Gil K, Callahan C, O'dell C, Pappo M, Moshe S, Shinnar S,. (1998) Complications of the ketogenic diet. Epilepsia 39: 744-748.
2. Freeman JM, Vining EP, Pillas DJ, Pyzik PL, Casey JC, Kelly LM,. (1998) The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. Pediatrics 102: 1358-1363.
3. Kang HC, Chung DE, Kim DW, Kim HD,. (2004) Early- and late-onset complications of the ketogenic diet for intractable epilepsy. Epilepsia 45: 1116-1123.
4. Kang HC, Lee HS, You SJ, Kang Du C, Ko TS, Kim HD,. (2007) Use of a modified Atkins diet in intractable childhood epilepsy. Epilepsia 48: 182-186.
5. Kossoff EH, Dorward JL,. (2008) The modified Atkins diet. Epilepsia, 49 (Suppl. 8): 37-41.
6. Kossoff EH, Mcgrogan JR, Bluml RM, Pillas DJ, Rubenstein JE, Vining EP,. (2006) A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy. Epilepsia 47: 421-424.
7. Kossoff EH, Turner Z, Bluml RM, Pyzik PL, Vining EP,. (2007) A randomized, crossover comparison of daily carbohydrate limits using the modified Atkins diet. Epilepsy Behav 10: 432-436.
8. Kossoff EH, Dorward JL, Molinero MR, Holden KR,. (2008a) The modified Atkins diet: a potential treatment for developing countries. Epilepsia 49: 1646-1647.
9. Kossoff EH, Rowley H, Sinha SR, Vining EP,. (2008b) A prospective study of the modified Atkins diet for intractable epilepsy in adults. Epilepsia 49: 316-319.
10. Miranda MJ, Mortensen M, Povlsen JH, Nielsen H, Beniczky S,. (2011) Danish study of a modified Atkins diet for medically intractable epilepsy in children: can we achieve the same results as with the classical ketogenic diet? Seizure 20: 151-155.
11. Neal EG, Chaffe H, Schwartz RH, Lawson MS, Edwards N, Fitzsimmons G, Whitney A, Cross JH,. (2008) The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Lancet Neurol 7: 500-506.
12. Patsalos PN, Duncan JS,. (1993) Antiepileptic drugs. A review of clinically significant drug interactions. Drug Saf 9: 156-184.
13. Peterson SJ, Tangney CC, Pimentel-Zablah EM, Hjelmgren B, Booth G, Berry-Kravis E,. (2005) Changes in growth and seizure reduction in children on the ketogenic diet as a treatment for intractable epilepsy. J Am Diet Assoc 105: 718-725.
14. Raju KN, Gulati S, Kabra M, Agarwala A, Sharma S, Pandey RM, Kalra V,. (2011) Efficacy of 4:1 (classic) versus 2.5:1 ketogenic ratio diets in refractory epilepsy in young children: a randomized open labeled study. Epilepsy Res 96: 96-100.
15. Sharma S, Gulati S, Kalra V, Agarwala A, Kabra M,. (2009) Seizure control and biochemical profile on the ketogenic diet in young children with refractory epilepsy-Indian experience. Seizure 18: 446-449.
16. Sharma S, Sankhyan N, Gulati S, Agarwala A,. (2012) Use of the modified Atkins diet in infantile spasms refractory to first-line treatment. Seizure 21: 45-48.
17. Stainman RS, Turner Z, Rubenstein JE, Kossoff EH,. (2007) Decreased relative efficacy of the ketogenic diet for children with surgically approachable epilepsy. Seizure 16: 615-619.
18. Weber S, Molgaard C, Karen taudorf, Uldall P,. (2009) Modified Atkins diet to children and adolescents with medical intractable epilepsy. Seizure 18: 237-240.