Reduced default mode network connectivity in treatment-resistant idiopathic generalized epilepsy

Epilepsia

Volumn 54, Issue 3, 2013, Pages 461-470

  Kay, Benjamin P ^a,b   Difrancesco, Mark W ^b   Privitera, Michael D ^c   Gotman, Jean ^d   Holland, Scott K ^b   Szaflarski, Jerzy P ^b,c,e  

^a UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Dual regression; Independent component analysis; Primary generalized epilepsy; Resting state functional connectivity; Seed based voxel correlation; Valproic acid

Indexed keywords

VALPROIC ACID;

ADULT; ARTICLE; BOLD SIGNAL; CONNECTOME; CONTROLLED STUDY; CUNEUS; DEFAULT MODE NETWORK CONNECTIVITY; ELECTROENCEPHALOGRAPHY; FEMALE; FEVER; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENERALIZED EPILEPSY; HIPPOCAMPUS; HUMAN; INDEPENDENT COMPONENT ANALYSIS; LINGUAL GYRUS; MAJOR CLINICAL STUDY; MALE; OCCIPITAL CORTEX; PRIORITY JOURNAL; TREATMENT RESISTANT EPILEPSY;

ADOLESCENT; ADULT; DOWN-REGULATION; EPILEPSY, GENERALIZED; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE NET; PROSPECTIVE STUDIES; TREATMENT FAILURE; TREATMENT OUTCOME; VALPROIC ACID; YOUNG ADULT;

EID: 84874669970     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12057     Document Type: Article

References (68)

1. Aghakhani Y, Bagshaw AP, Bénar CG, Hawco C, Andermann F, Dubeau F, Gotman J,. (2004) fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain 127: 1127-1144.
2. Allen PJ, Josephs O, Turner R,. (2000) A method for removing imaging artifact from continuous EEG recorded during functional MRI. Neuroimage 12: 230-239.
3. Andersson JLR, Jenkinson M, Smith S,. (2007a) Non-linear optimisation. FMRIB technical report TR07JA1. www.fmrib.ox.ac.uk/analysis/techrep.
4. Andersson JLR, Jenkinson M, Smith S,. (2007b) Non-linear registration, aka Spatial normalisation. FMRIB technical report TR07JA2. www.fmrib.ox.ac.uk/ analysis/techrep.
5. Bai X, Guo J, Killory B, Vestal M, Berman R, Negishi M, Danielson N, Novotny EJ, Constable RT, Blumenfeld H,. (2011) Resting functional connectivity between the hemispheres in childhood absence epilepsy. Neurology 76: 1960-1967.
6. Calhoun VD, Adali T, Pearlson GD, Pekar JJ,. (2001) A method for making group inferences from functional MRI data using independent component analysis. Hum Brain Mapp 14: 140-151.
7. Calhoun VD, Liu J, Adali T,. (2009) A review of group ICA for fMRI data and ICA for joint inference of imaging, genetic, and ERP data. Neuroimage 45: S163-S172.
8. Commission on Classification and Terminology of the International League Against Epilepsy. (1989) Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 30: 389-399.
9. Contreras D, Destexhe A, Sejnowski TJ, Steriade M,. (1996) Control of spatiotemporal coherence of a thalamic oscillation by corticothalamic feedback. Science 274: 771-774.
10. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, Quigley MA, Meyerand ME,. (2001) Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data. AJNR Am J Neuroradiol 22: 1326-1333.
11. Cox RW,. (1996) AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 29: 162-173.
12. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF,. (2006) Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 103: 13848-13853.
13. Danielson NB, Guo JN, Blumenfeld H,. (2011) The default mode network and altered consciousness in epilepsy. Behav Neurol 24: 55-65.
14. DiFrancesco MW, Holland SK, Szaflarski JP,. (2008) Simultaneous EEG/functional magnetic resonance imaging at 4 Tesla: correlates of brain activity to spontaneous alpha rhythm during relaxation. J Clin Neurophysiol 25: 255-264.
15. Duewell S, Wolff SD, Wen H, Balaban RS, Jezzard P,. (1996) MR imaging contrast in human brain tissue: assessment and optimization at 4 T. Radiology 199: 780-786.
16. Engel J Jr,. (1993) Surgical treatment of the epilepsies, 2nd ed. Raven Press, New York, Chapters 9-10.
17. Espay AJ, Schmithorst VJ, Szaflarski JP,. (2008) Chronic isolated hemifacial spasm as a manifestation of epilepsia partialis continua. Epilepsy Behav 12: 332-336.
18. Faught E,. (2004) Treatment of refractory primary generalized epilepsy. Rev Neurol Dis 1: S34-S43.
19. Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE,. (2009) Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci U S A 106: 7209-7214.
20. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME,. (2005) The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci U S A 102: 9673-9678.
21. French JA, Kanner AM, Bautista J, Abou-Khalil B, Browne T, Harden CL, Theodore WH, Bazil C, Stern J, Schachter SC, Bergen D, Hirtz D, Montouris GD, Nespeca M, Gidal B, Marks WJ Jr, Turk WR, Fischer JH, Bourgeois B, Wilner A, Faught RE Jr, Sachdeo RC, Beydoun A, Glauser TA,. (2004) Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 62: 1261-1273.
22. Gotman J, Grova C, Bagshaw A, Kobayashi E, Aghakhani Y, Dubeau F,. (2005) Generalized epileptic discharges show thalamocortical activation and suspension of the default state of the brain. Proc Natl Acad Sci U S A 102: 15236-15240.
23. Gotman J, Kobayashi E, Bagshaw AP, Bénar CG, Dubeau F,. (2006) Combining EEG and fMRI: a multimodal tool for epilepsy research. J Magn Reson Imaging 23: 906-920.
24. Greicius MD, Krasnow B, Reiss AL, Menon V,. (2003) Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A 100: 253-258.
25. Greicius MD, Srivastava G, Reiss AL, Menon V,. (2004) Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci USA 101: 4637-4642.
26. Greicius MD, Supekar K, Menon V, Dougherty RF,. (2009) Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 19: 72-78.
27. Groomes LB, Pyzik PL, Turner Z, Dorward JL, Goode VH, Kossoff EH,. (2011) Do patients with absence epilepsy respond to ketogenic diets? J Child Neurol 26: 160-165.
28. Holland KD, Monahan S, Morita D, Vartzelis G, Glauser TA,. (2010) Valproate in children with newly diagnosed idiopathic generalized epilepsy. Acta Neurol Scand 121: 149-153.
29. Hua K, Zhang J, Wakana S, Jiang H, Li X, Reich DS, Calabresi PA, Pekar JJ, van Zijl PC, Mori S,. (2008) Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification. Neuroimage 39: 336-347.
30. Jallon P, Latour P,. (2005) Epidemiology of idiopathic generalized epilepsies. Epilepsia 46: 10-14.
31. Jenkinson M, Smith S,. (2001) A global optimisation method for robust affine registration of brain images. Med Image Anal 5: 143-156.
32. Jenkinson M, Bannister P, Brady M, Smith S,. (2002) Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17: 825-841.
33. Jones DT, Mateen FJ, Lucchinetti CF, Jack CR Jr,., Welker KM,. (2011) Default mode network disruption secondary to a lesion in the anterior thalamus. Arch Neurol 68: 242-247.
34. Kay BP, Meng X, Difrancesco MW, Holland SK, Szaflarski JP,. (2012) Moderating effects of music on resting state networks. Brain Res 1447: 53-64.
35. Killory BD, Bai X, Negishi M, Vega C, Spann MN, Vestal M, Guo J, Berman R, Danielson N, Trejo J, Shisler D, Novotny EJ Jr, Constable RT, Blumenfeld H,. (2011) Impaired attention and network connectivity in childhood absence epilepsy. Neuroimage 56: 2209-2217.
36. Kostov H, Larsson PG, Røste GK,. (2007) Is vagus nerve stimulation a treatment option for patients with drug-resistant idiopathic generalized epilepsy? Acta Neurol Scand Suppl 187: 55-58.
37. Labar D, Murphy J, Tecoma E,. (1999) Vagus nerve stimulation for medication-resistant generalized epilepsy. Neurology 52: 1510-1512.
38. Lagerlund TD, Sharbrough FW, Busacker NE,. (1997) Spatial filtering of multichannel electroencephalographic recordings through principal component analysis by singular value decomposition. J Clin Neurophysiol 14: 73-82.
39. Laufs H, Lengler U, Hamandi K, Kleinschmidt A, Krakow K,. (2006) Linking generalized spike-and-wave discharges and resting state brain activity by using EEG/fMRI in a patient with absence seizures. Epilepsia 47: 444-448.
40. Luo C, Li Q, Lai Y, Xia Y, Qin Y, Liao W, Li S, Zhou D, Yao D, Gong Q,. (2011) Altered functional connectivity in default mode network in absence epilepsy: a resting-state fMRI study. Hum Brain Mapp 32: 438-449.
41. Ma L, Wang B, Chen X, Xiong J,. (2007) Detecting functional connectivity in the resting brain: a comparison between ICA and CCA. Magn Reson Imaging 25: 47-56.
42. McGill ML, Devinsky O, Kelly C, Milham M, Castellanos FX, Quinn BT, DuBois J, Young JR, Carlson C, French J, Kuzniecky R, Halgren E, Thesen T,. (2012) Default mode network abnormalities in idiopathic generalized epilepsy. Epilepsy Behav 23: 353-359.
43. Moeller F, Siebner HR, Wolff S, Muhle H, Boor R, Granert O, Jansen O, Stephani U, Siniatchkin M,. (2008a) Changes in activity of striato-thalamo- cortical network precede generalized spike wave discharges. Neuroimage 39: 1839-1849.
44. Moeller F, Siebner HR, Wolff S, Muhle H, Granert O, Jansen O, Stephani U, Siniatchkin M,. (2008b) Simultaneous EEG-fMRI in drug-naive children with newly diagnosed absence epilepsy. Epilepsia 49: 1510-1519.
45. Ng M, Devinsky O,. (2004) Vagus nerve stimulation for refractory idiopathic generalised epilepsy. Seizure 13: 176-178.
46. Opeskin K, Kalnins RM, Halliday G, Cartwright H, Berkovic SF,. (2000) Idiopathic generalized epilepsy: lack of significant microdysgenesis. Neurology 55: 1101-1106.
47. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE,. (2012) Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59: 2142-2154.
48. R Development Core Team. (2011) R: a language and environment for statistical computing. Available at: http://www.R-project.org (Accessed August 8, 2012).
49. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL,. (2001) A default mode of brain function. Proc Natl Acad Sci U S A 98: 676-682.
50. Sambataro F, Murty VP, Callicott JH, Tan HY, Das S, Weinberger DR, Mattay VS,. (2010) Age-related alterations in default mode network: impact on working memory performance. Neurobiol Aging 31: 839-852.
51. Schmithorst VJ,. (2005) Separate cortical networks involved in music perception: preliminary functional MRI evidence for modularity of music processing. Neuroimage 25: 444-451.
52. Schmithorst VJ, Holland SK,. (2004) Comparison of three methods for generating group statistical inferences from independent component analysis of functional magnetic resonance imaging data. J Magn Reson Imaging 19: 365-368.
53. Schmithorst VJ, Dardzinski BJ, Holland SK,. (2001) Simultaneous correction of ghost and geometric distortion artifacts in EPI using a multiecho reference scan. IEEE Trans Med Imaging 20: 535-539.
54. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TE, Johansen-Berg H, Bannister PR, De Luca M, Drobnjak I, Flitney DE, Niazy RK, Saunders J, Vickers J, Zhang Y, De Stefano N, Brady JM, Matthews PM,. (2004) Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23: S208-S219.
55. Szaflarski JP, Allendorfer JB,. (2012) Topiramate and its effect on fMRI of language in patients with right or left temporal lobe epilepsy. Epilepsy Behav 24: 74-80.
56. Szaflarski JP, Rackley AY, Lindsell CJ, Szaflarski M, Yates SL,. (2008) Seizure control in patients with epilepsy: the physician vs. medication factors. BMC Health Serv Res 8: 264.
57. Szaflarski JP, Lindsell CJ, Zakaria T, Banks C, Privitera MD,. (2010a) Seizure control in patients with idiopathic generalized epilepsies: EEG determinants of medication response. Epilepsy Behav 17: 525-530.
58. Szaflarski JP, DiFrancesco MW, Hirschauer T, Banks C, Privitera MD, Gotman J, Holland SK,. (2010b) Cortical and subcortical contributions to absence seizure onset examined with EEG/fMRI. Epilepsy Behav 18: 404-413.
59. Tyvaert L, Chassagnon S, Sadikot A, LeVan P, Dubeau F, Gotman J,. (2009) Thalamic nuclei activity in idiopathic generalized epilepsy: an EEG-fMRI study. Neurology 73: 2018-2022.
60. Uǧurbil K, Garwood M, Ellermann J, Hendrich K, Hinke R, Hu X, Kim SG, Menon R, Merkle H, Ogawa S,. (1993) Imaging at high magnetic fields: initial experiences at 4 T. Magn Reson Q 9: 259-277.
61. Upchurch K, Stern JM,. (2006) Epilepsy surgery in adults. Available at: http://www.medmerits.com/index.php/article/epilepsy-surgery-in-adults (Accessed August 8, 2012).
62. Van Dijk KR, Sabuncu MR, Buckner RL,. (2012) The influence of head motion on intrinsic functional connectivity MRI. Neuroimage 59: 431-438.
63. Wakana S, Caprihan A, Panzenboeck MM, Fallon JH, Perry M, Gollub RL, Hua K, Zhang J, Jiang H, Dubey P, Blitz A, van Zijl P, Mori S,. (2007) Reproducibility of quantitative tractography methods applied to cerebral white matter. Neuroimage 36: 630-644.
64. Weissenbacher A, Kasess C, Gerstl F, Lanzenberger R, Moser E, Windischberger C,. (2009) Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage 47: 1408-1416.
65. Whitcher B, Schmid VJ, Thornton A,. (2011) Working with the DICOM and NIfTI data standards in R. J Stat Softw 44: 1-28.
66. Yenjun S, Harvey AS, Marini C, Newton MR, King MA, Berkovic SF,. (2003) Epilepsia 44: 242-246.
67. Zhang D, Snyder AZ, Fox MD, Sansbury MW, Shimony JS, Raichle ME,. (2008) Intrinsic functional relations between human cerebral cortex and thalamus. J Neurophysiol 100: 1740-1748.
68. Zhang Z, Liao W, Chen H, Mantini D, Ding JR, Xu Q, Wang Z, Yuan C, Chen G, Jiao Q, Lu G,. (2011) Altered functional-structural coupling of large-scale brain networks in idiopathic generalized epilepsy. Brain 134: 2912-2928.