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Volumn 33, Issue 3, 2013, Pages 381-388

Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers

Author keywords

blood brain barrier; confocal microscopy; endothelium; pharmacology; physiology

Indexed keywords

FINGOLIMOD; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84874665034     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2012.174     Document Type: Article
Times cited : (41)

References (30)
  • 1
    • 27744479194 scopus 로고    scopus 로고
    • Involvement of N-terminal-extended form of sphingosine kinase 2 in serumdependent regulation of cell proliferation and apoptosis
    • Okada T, Ding G, Sonoda H, Kajimoto T, Haga Y, Khosrowbeygi A et al. Involvement of N-terminal-extended form of sphingosine kinase 2 in serumdependent regulation of cell proliferation and apoptosis. J Biol Chem 2005; 280: 36318-36325.
    • (2005) J Biol Chem , vol.280 , pp. 36318-36325
    • Okada, T.1    Ding, G.2    Sonoda, H.3    Kajimoto, T.4    Haga, Y.5    Khosrowbeygi, A.6
  • 2
    • 0242710592 scopus 로고    scopus 로고
    • Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2\+ mobilization independently of G-protein-coupled receptors
    • Meyer ZU, Heringdorf D, Liliom K, Schaefer M, Danneberg K, Jaggar JH et al. Photolysis of intracellular caged sphingosine-1-phosphate causes Ca2\+ mobilization independently of G-protein-coupled receptors. FEBS Lett 2003; 554: 443-449.
    • (2003) FEBS Lett , vol.554 , pp. 443-449
    • Meyer, Z.U.1    Heringdorf, D.2    Liliom, K.3    Schaefer, M.4    Danneberg, K.5    Jaggar, J.H.6
  • 3
  • 4
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: An enigmatic signalling lipid
    • Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 2003; 4: 397-407.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 397-407
    • Spiegel, S.1    Milstien, S.2
  • 7
    • 78751525273 scopus 로고    scopus 로고
    • The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720
    • Hisano Y, Kobayashi N, Kawahara A, Yamaguchi A, Nishi T. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720. J Biol Chem 2011; 286: 1758-1766.
    • (2011) J Biol Chem , vol.286 , pp. 1758-1766
    • Hisano, Y.1    Kobayashi, N.2    Kawahara, A.3    Yamaguchi, A.4    Nishi, T.5
  • 8
    • 58849083220 scopus 로고    scopus 로고
    • The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors
    • Kawahara A, Nishi T, Hisano Y, Fukui H, Yamaguchi A, Mochizuki N. The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors. Science 2009; 323: 524-527.
    • (2009) Science , vol.323 , pp. 524-527
    • Kawahara, A.1    Nishi, T.2    Hisano, Y.3    Fukui, H.4    Yamaguchi, A.5    Mochizuki, N.6
  • 9
    • 84859727262 scopus 로고    scopus 로고
    • The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
    • Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T et al. The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J Clin Invest 2012; 122: 1416-1426.
    • (2012) J Clin Invest , vol.122 , pp. 1416-1426
    • Fukuhara, S.1    Simmons, S.2    Kawamura, S.3    Inoue, A.4    Orba, Y.5    Tokudome, T.6
  • 11
    • 77953687856 scopus 로고    scopus 로고
    • Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier
    • Miller DS. Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier. Trends Pharmacol Sci 2010; 31: 246-254.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 246-254
    • Miller, D.S.1
  • 12
    • 84866844026 scopus 로고    scopus 로고
    • Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain
    • Cannon RE, Peart JC, Hawkins BT, Campos CR, Miller DS. Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain. Proc Natl Acad Sci USA 2012; 109: 15930-15935.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 15930-15935
    • Cannon, R.E.1    Peart, J.C.2    Hawkins, B.T.3    Campos, C.R.4    Miller, D.S.5
  • 13
    • 33646754516 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins: Expression and function in the central nervous system
    • Dallas S, Miller DS, Bendayan R. Multidrug resistance-associated proteins: expression and function in the central nervous system. Pharmacol Rev 2006; 58: 140-161.
    • (2006) Pharmacol Rev , vol.58 , pp. 140-161
    • Dallas, S.1    Miller, D.S.2    Bendayan, R.3
  • 14
    • 77954920933 scopus 로고    scopus 로고
    • Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 down-regulates blood-brain barrier breast cancer resistance protein
    • Hartz AM, Madole EK, Miller DS, Bauer B. Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 down-regulates blood-brain barrier breast cancer resistance protein. J Pharmacol Exp Ther 2010; 334: 467-476.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 467-476
    • Hartz, A.M.1    Madole, E.K.2    Miller, D.S.3    Bauer, B.4
  • 15
    • 27244461958 scopus 로고
    • P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules
    • Schramm U, Fricker G, Wenger R, Miller DS. P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules. Am J Physiol 1995; 268: F46-F52.
    • (1995) Am J Physiol , vol.268
    • Schramm, U.1    Fricker, G.2    Wenger, R.3    Miller, D.S.4
  • 16
    • 84864565346 scopus 로고    scopus 로고
    • ABC transporter function and regulation at the blood-spinal cord barrier
    • Campos CR, Schroter C, Wang X, Miller DS. ABC transporter function and regulation at the blood-spinal cord barrier. J Cereb Blood Flow Metab 2012; 32: 1559-1566.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1559-1566
    • Campos, C.R.1    Schroter, C.2    Wang, X.3    Miller, D.S.4
  • 17
    • 4944230261 scopus 로고    scopus 로고
    • Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1
    • Hartz AM, Bauer B, Fricker G, Miller DS. Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1. Mol Pharmacol 2004; 66: 387-394.
    • (2004) Mol Pharmacol , vol.66 , pp. 387-394
    • Hartz, A.M.1    Bauer, B.2    Fricker, G.3    Miller, D.S.4
  • 18
    • 79957610938 scopus 로고    scopus 로고
    • The outs and the ins of sphingosine-1-phosphate in immunity
    • Spiegel S, Milstien S. The outs and the ins of sphingosine-1-phosphate in immunity. Nat Rev Immunol 2011; 11: 403-415.
    • (2011) Nat Rev Immunol , vol.11 , pp. 403-415
    • Spiegel, S.1    Milstien, S.2
  • 19
    • 31044447881 scopus 로고    scopus 로고
    • Rapid modulation of P-glycoproteinmediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide
    • Hartz AM, Bauer B, Fricker G, Miller DS. Rapid modulation of P-glycoproteinmediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide. Mol Pharmacol 2006; 69: 462-470.
    • (2006) Mol Pharmacol , vol.69 , pp. 462-470
    • Hartz, A.M.1    Bauer, B.2    Fricker, G.3    Miller, D.S.4
  • 20
    • 77954242152 scopus 로고    scopus 로고
    • Activation of PKC isoform beta(I) at the bloodbrain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain
    • Rigor RR, Hawkins BT, Miller DS. Activation of PKC isoform beta(I) at the bloodbrain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain. J Cereb Blood Flow Metab 2010; 30: 1373-1383.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1373-1383
    • Rigor, R.R.1    Hawkins, B.T.2    Miller, D.S.3
  • 22
    • 54949103249 scopus 로고    scopus 로고
    • ABCC1: A gateway for pharmacological compounds to the ischaemic brain
    • Kilic E, Spudich A, Kilic U, Rentsch KM, Vig R, Matter CM et al. ABCC1: a gateway for pharmacological compounds to the ischaemic brain. Brain 2008; 131: 2679-2689.
    • (2008) Brain , vol.131 , pp. 2679-2689
    • Kilic, E.1    Spudich, A.2    Kilic, U.3    Rentsch, K.M.4    Vig, R.5    Matter, C.M.6
  • 24
    • 3242682550 scopus 로고    scopus 로고
    • Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier
    • Berezowski V, Landry C, Dehouck MP, Cecchelli R, Fenart L. Contribution of glial cells and pericytes to the mRNA profiles of P-glycoprotein and multidrug resistance-associated proteins in an in vitro model of the blood-brain barrier. Brain Res 2004; 1018: 1-9.
    • (2004) Brain Res , vol.1018 , pp. 1-9
    • Berezowski, V.1    Landry, C.2    Dehouck, M.P.3    Cecchelli, R.4    Fenart, L.5
  • 25
    • 81755174316 scopus 로고    scopus 로고
    • Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier
    • McGuire PG, Rangasamy S, Maestas J, Das A. Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulates the retinal endothelial cell barrier. Arterioscler Thromb Vasc Biol 2011; 31: e107-e115.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31
    • McGuire, P.G.1    Rangasamy, S.2    Maestas, J.3    Das, A.4
  • 26
    • 77956268005 scopus 로고    scopus 로고
    • Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay
    • Hawkins BT, Rigor RR, Miller DS. Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay. J Cereb Blood Flow Metab 2010; 30: 1593-1597.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1593-1597
    • Hawkins, B.T.1    Rigor, R.R.2    Miller, D.S.3
  • 28
    • 80052490064 scopus 로고    scopus 로고
    • Mammalian multidrug-resistance proteins (MRPs
    • Slot AJ, Molinski SV, Cole SP. Mammalian multidrug-resistance proteins (MRPs). Essays Biochem 2011; 50: 179-207.
    • (2011) Essays Biochem , vol.50 , pp. 179-207
    • Slot, A.J.1    Molinski, S.V.2    Cole, S.P.3
  • 29
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo-and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • Deeley RG, Westlake C, Cole SP. Transmembrane transport of endo-and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol Rev 2006; 86: 849-899.
    • (2006) Physiol Rev , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.3
  • 30
    • 20244386956 scopus 로고    scopus 로고
    • Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
    • Wijnholds J, Evers R, van Leusden MR, Mol CA, Zaman GJ, Mayer U et al. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nat Med 1997; 3: 1275-1279.
    • (1997) Nat Med , vol.3 , pp. 1275-1279
    • Wijnholds, J.1    Evers, R.2    Van Leusden, M.R.3    Mol, C.A.4    Zaman, G.J.5    Mayer, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.