Letter to the editor regarding the report of Duboc et al: Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel disease

Gut

Volumn 62, Issue 4, 2013, Pages 654-655

  Jones, Mitchell L ^a,b   Martoni, Christopher J ^b   Prakash, Satya ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b Micropharma Limited   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BILE SALT HYDROLASE; C REACTIVE PROTEIN; CHOLESTEROL; G PROTEIN COUPLED RECEPTOR; HYDROLASE; INTERLEUKIN 6; LIPID; PLACEBO; PROBIOTIC AGENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; BILE ACID METABOLISM; CONJUGATION; DISEASE ASSOCIATION; ENTERITIS; ENZYME ACTIVITY; GASTROINTESTINAL TRACT FUNCTION; HUMAN; HYPERCHOLESTEROLEMIA; INTESTINE FLORA; IRRITABLE COLON; LACTOBACILLUS REUTERI; LETTER; LIPID ABSORPTION; MULTICENTER STUDY (TOPIC); NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT OUTCOME;

ANIMALS; BILE ACIDS AND SALTS; HUMANS; INFLAMMATORY BOWEL DISEASES;

EID: 84874664582     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2012-303867     Document Type: Letter

References (4)

1. Duboc H, Rajca S, Rainteau D, et al. Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut 2013;62:531-9.
2. Fiorucci S, Cipriani S, Mencarelli A, et al. Counterregulatory role of bile acid activated receptors in immunity and inflammation. Curr Mol Med 2010;10:579-95.
3. Pols TW, Nomura M, Harach T, et al. TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. Cell Metab 2011;14:747-57.
4. Jones ML, Martoni CJ, Prakash S. Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. Eur J Clin Nutr Published Online First: 19 Sept 2012. doi: 10.1038/ejcn. 2012.126.