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Volumn 9, Issue 3, 2013, Pages 128-130

Diabetic nephropathy: Could problems with bardoxolone methyl have been predicted?

Author keywords

[No Author keywords available]

Indexed keywords

BARDOXOLONE METHYL; DH 404; RAMIPRIL; RTA 405; UNCLASSIFIED DRUG;

EID: 84874653586     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2013.13     Document Type: Review
Times cited : (26)

References (10)
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    • Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD
    • Pergola, P. E. et al. Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD. Am. J. Nephrol. 33, 469-476 (2011).
    • (2011) Am. J. Nephrol. , vol.33 , pp. 469-476
    • Pergola, P.E.1
  • 2
    • 79960855656 scopus 로고    scopus 로고
    • Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • Pergola, P. E. et al. Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N. Engl. J. Med. 365, 327-336 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , pp. 327-336
    • Pergola, P.E.1
  • 3
    • 84877930774 scopus 로고    scopus 로고
    • Analogues of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects
    • Zoja, C. et al. Analogues of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects. Am. J. Physiol. Renal Physiol. http://dx.doi.org/doi:10.1152/ajprenal.00376.2012.
    • Am. J. Physiol. Renal Physiol
    • Zoja, C.1
  • 4
    • 79955763790 scopus 로고    scopus 로고
    • Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARgamma, and HO-1
    • Wu, Q. Q. et al. Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARgamma, and HO-1. Am. J. Physiol. Renal Physiol. 300, F1180-F1192 (2011).
    • (2011) Am. J. Physiol. Renal Physiol. , vol.300
    • Wu, Q.Q.1
  • 5
    • 77957219845 scopus 로고    scopus 로고
    • Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity
    • Aleksunes, L. M. et al. Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity. J. Pharmacol. Exp. Ther. 335, 2-12 (2010).
    • (2010) J. Pharmacol. Exp. Ther. , vol.335 , pp. 2-12
    • Aleksunes, L.M.1
  • 6
    • 31444451184 scopus 로고    scopus 로고
    • Prediction progression and prevention of diabetic Nephropathy. The Minkowski lecture 2005
    • Rossing, P. Prediction, progression and prevention of diabetic nephropathy. The Minkowski Lecture 2005. Diabetologia 49, 11-19 (2006).
    • (2006) Diabetologia , vol.49 , pp. 11-19
    • Rossing, P.1
  • 7
    • 80455173513 scopus 로고    scopus 로고
    • Bardoxolone methyl, chronic kidney disease, and type 2 diabetes
    • McMahon, G. M. & Forman, J. P. Bardoxolone methyl, chronic kidney disease, and type 2 diabetes. N. Engl. J. Med. 365, 1746-1747 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1746-1747
    • McMahon, G.M.1    Forman, J.P.2
  • 8
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    • Reata Pharmaceuticals
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    • (2012) Company Statement: Termination of the BEACON Trial
  • 9
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    • Reduction in albuminuria predicts a beneficial effect on diminishing the progression of human diabetic nephropathy during antihypertensive treatment
    • Rossing, P., Hommel, E., Smidt, U. M. & Parving, H.-H. Reduction in albuminuria predicts a beneficial effect on diminishing the progression of human diabetic nephropathy during antihypertensive treatment. Diabetologia 37, 511-516 (1994).
    • (1994) Diabetologia , vol.37 , pp. 511-516
    • Rossing, P.1    Hommel, E.2    Smidt, U.M.3    Parving, H.-H.4
  • 10
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    • Albuminuria: A target for treatment of type 2 diabetic nephropathy
    • de Zeeuw, D. Albuminuria: a target for treatment of type 2 diabetic nephropathy. Semin. Nephrol. 27, 172-181 (2007).
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.