Disruption of prefrontal cortical-hippocampal balance in a developmental model of schizophrenia: Reversal by sulpiride

International Journal of Neuropsychopharmacology

Volumn 16, Issue 3, 2013, Pages 507-512

  Belujon, Pauline ^a   Patton, Mary H ^a   Grace, Anthony A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Antipsychotic; nucleus accumbens; synaptic plasticity

Indexed keywords

METHYLAZOXYMETHANOL ACETATE; SULPIRIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DIATHERMY; DISEASE COURSE; ELECTROSTIMULATION THERAPY; EVOKED RESPONSE; FEMALE; HIPPOCAMPUS; LATENT PERIOD; LONG TERM DEPRESSION; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; SPIKE WAVE; SYNAPTIC EFFICACY;

ANIMALS; ANTIPSYCHOTIC AGENTS; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; METHYLAZOXYMETHANOL ACETATE; PREFRONTAL CORTEX; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SCHIZOPHRENIA; SULPIRIDE;

EID: 84874636320     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S146114571200106X     Document Type: Article

References (23)

1. Belujon P, Grace AA (2008). Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow. Journal of Neuroscience 28, 9797-9805.
2. Belujon P, Patton MH, Grace AA (2011). Altered hippocampal-accumbens synaptic plasticity in a developmental animal model of schizophrenia. Program No. 900.16 2011 Neuroscience Meeting Planner. Washington, DC: Society for Neuroscience.
3. Bogerts B, Lieberman JA, Ashtari M, Bilder RM, et al. (1993). Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biological Psychiatry 33, 236-246. (Pubitemid 23091498)
4. Flagstad P, Mork A, Glenthoj BY, van Beek J, et al. (2004). Disruption of neurogenesis on gestational day 17 in the rat causes behavioral changes relevant to positive and negative schizophrenia symptoms and alters amphetamine-induced dopamine release in nucleus accumbens. Neuropsychopharmacology 29, 2052-2064. (Pubitemid 39486557)
5. Floresco SB, Magyar O, Ghods-Sharifi S, Vexelman C, et al. (2006). Multiple dopamine receptor subtypes in the medial prefrontal cortex of the rat regulate set-shifting. Neuropsychopharmacology 31, 297-309. (Pubitemid 43113395)
6. Goldman-Rakic PS (1990). Cellular and circuit basis of working memory in prefrontal cortex of nonhuman primates. Progress in Brain Research 85, 325-335; discussion 335-326.
7. Goto Y, Grace AA (2005). Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior. Nature Neuroscience 8, 805-812. (Pubitemid 43085848)
8. Goto Y, Grace AA (2006). Alterations in medial prefrontal cortical activity and plasticity in rats with disruption of cortical development. Biological Psychiatry, 60, 1259-1267. (Pubitemid 44693541)
9. Gourevitch R, Rocher C, Le Pen G, Krebs MO, et al. (2004). Working memory deficits in adult rats after prenatal disruption of neurogenesis. Behavioural Pharmacology 15, 287-292. (Pubitemid 39062558)
10. Grace AA (2012). Dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia. Neuropharmacology 62, 1342-1348.
11. Jarrard LE (1995). What does the hippocampus really do? Behavioural Brain Research 71, 1-10.
12. Lavin A, Moore HM, Grace AA (2005). Prenatal disruption of neocortical development alters prefrontal cortical neuron responses to dopamine in adult rats. Neuropsychopharmacology 30, 1426-1435. (Pubitemid 41153114)
13. Lewis DA, Moghaddam B (2006). Cognitive dysfunction in schizophrenia : convergence of gamma-aminobutyric acid and glutamate alterations. Archives of Neurology 63, 1372-1376. (Pubitemid 44547546)
14. Lodge DJ, Behrens MM, Grace AA (2009). A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. Journal of Neuroscience 29, 2344-2354.
15. Lodge DJ, Grace AA (2007). Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. Journal of Neuroscience 27, 11424-11430. (Pubitemid 47621327)
16. Meyer-Lindenberg A, Poline JB, Kohn PD, Holt JL, et al. (2001). Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. American Journal of Psychiatry, 158, 1809-1817. (Pubitemid 33054773)
17. Moore H, Jentsch JD, Ghajarnia M, Geyer MA, et al. (2006). A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biological Psychiatry 60, 253-264. (Pubitemid 44093447)
18. Ongur D, Price JL (2000). The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cerebral Cortex 10, 206-219. (Pubitemid 30159289)
19. Paxinos G, Watson C (1996) The Rat Brain in Stereotatic Coordinates. San Diego, CA: Academic Press.
20. Saks E (2008). The Center Cannot Hold: My Journey Through Madness. New York: Hyperion.
21. Schultz W (2010). Dopamine signals for reward value and risk : basic and recent data. Behavioural and Brain Functions 6, 24.
22. Sesack SR, Grace AA (2010). Cortico-basal ganglia reward network: microcircuitry. Neuropsychopharmacology, 35, 27-47.
23. Tamminga CA, Thaker GK, Buchanan R, Kirkpatrick B, et al. (1992). Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Archives of General Psychiatry, 49, 522-530.