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Volumn 8, Issue 3, 2013, Pages

Multiple Delivery of siRNA against Endoglin into Murine Mammary Adenocarcinoma Prevents Angiogenesis and Delays Tumor Growth

Author keywords

[No Author keywords available]

Indexed keywords

ENDOGLIN; MESSENGER RNA; SMALL INTERFERING RNA;

EID: 84874625300     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058723     Document Type: Article
Times cited : (43)

References (49)
  • 1
    • 80053186583 scopus 로고    scopus 로고
    • Controllingangiogenesis by two unique TGF-beta type I receptor signaling pathways
    • Orlova VV, Liu Z, Goumans MJ, ten Dijke P, (2011) Controllingangiogenesis by two unique TGF-beta type I receptor signaling pathways. HistolHistopathol 26: 1219-1230.
    • (2011) HistolHistopathol , vol.26 , pp. 1219-1230
    • Orlova, V.V.1    Liu, Z.2    Goumans, M.J.3    ten Dijke, P.4
  • 2
    • 53849106782 scopus 로고    scopus 로고
    • VEGFand Delta-Notch: interacting signalling pathways in tumour angiogenesis
    • Thurston G, Kitajewski J, (2008) VEGFand Delta-Notch: interacting signalling pathways in tumour angiogenesis. Br J Cancer 99: 1204-1209.
    • (2008) Br J Cancer , vol.99 , pp. 1204-1209
    • Thurston, G.1    Kitajewski, J.2
  • 3
    • 41049094560 scopus 로고    scopus 로고
    • Endoglin in angiogenesis and vascular diseases
    • ten Dijke P, Goumans MJ, Pardali E, (2008) Endoglin in angiogenesis and vascular diseases. Angiogenesis 11: 79-89.
    • (2008) Angiogenesis , vol.11 , pp. 79-89
    • ten Dijke, P.1    Goumans, M.J.2    Pardali, E.3
  • 4
    • 84856710142 scopus 로고    scopus 로고
    • Structural and functional insights into endoglin ligandrecognition and binding
    • Alt A, Miguel-Romero L, Donderis J, Aristorena M, Blanco FJ, et al. (2012) Structural and functional insights into endoglin ligandrecognition and binding. PLoS One 7: e29948.
    • (2012) PLoS One , vol.7
    • Alt, A.1    Miguel-Romero, L.2    Donderis, J.3    Aristorena, M.4    Blanco, F.J.5
  • 5
    • 0029611184 scopus 로고
    • Up-regulationof endoglin on vascular endothelial cells in human solid tumors: implicationsfor diagnosis and therapy
    • Burrows FJ, Derbyshire EJ, Tazzari PL, Amlot P, Gazdar AF, et al. (1995) Up-regulationof endoglin on vascular endothelial cells in human solid tumors: implicationsfor diagnosis and therapy. Clin Cancer Res 1: 1623-1634.
    • (1995) Clin Cancer Res , vol.1 , pp. 1623-1634
    • Burrows, F.J.1    Derbyshire, E.J.2    Tazzari, P.L.3    Amlot, P.4    Gazdar, A.F.5
  • 6
    • 42249110348 scopus 로고    scopus 로고
    • Endoglin (CD105): a marker of tumor vasculature and potentialtarget for therapy
    • Dallas NA, Samuel S, Xia L, Fan F, Gray MJ, et al. (2008) Endoglin (CD105): a marker of tumor vasculature and potentialtarget for therapy. Clin Cancer Res 14: 1931-1937.
    • (2008) Clin Cancer Res , vol.14 , pp. 1931-1937
    • Dallas, N.A.1    Samuel, S.2    Xia, L.3    Fan, F.4    Gray, M.J.5
  • 7
    • 0032908133 scopus 로고    scopus 로고
    • Elevatedexpression of endoglin, a component of the TGF-beta-receptorcomplex, correlates with proliferation of tumor endothelial cells
    • Miller DW, Graulich W, Karges B, Stahl S, Ernst M, et al. (1999) Elevatedexpression of endoglin, a component of the TGF-beta-receptorcomplex, correlates with proliferation of tumor endothelial cells. Int J Cancer 81: 568-572.
    • (1999) Int J Cancer , vol.81 , pp. 568-572
    • Miller, D.W.1    Graulich, W.2    Karges, B.3    Stahl, S.4    Ernst, M.5
  • 8
    • 0034060755 scopus 로고    scopus 로고
    • Imagingof tumour neovasculature by targeting the TGF-beta binding receptorendoglin
    • Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R, (2000) Imagingof tumour neovasculature by targeting the TGF-beta binding receptorendoglin. Eur J Cancer 36: 675-681.
    • (2000) Eur J Cancer , vol.36 , pp. 675-681
    • Bredow, S.1    Lewin, M.2    Hofmann, B.3    Marecos, E.4    Weissleder, R.5
  • 9
    • 1342330882 scopus 로고    scopus 로고
    • Perfusion of Tc-99(m)-labeled CD105 Mab into kidneysfrom patients with renal carcinoma suggests that CD105 is a promising vasculartarget
    • Costello B, Chenggang LG, Duff S, Butterworth D, Khan A, et al. (2004) Perfusion of Tc-99(m)-labeled CD105 Mab into kidneysfrom patients with renal carcinoma suggests that CD105 is a promising vasculartarget. International Journal of Cancer 109: 436-441.
    • (2004) International Journal of Cancer , vol.109 , pp. 436-441
    • Costello, B.1    Chenggang, L.G.2    Duff, S.3    Butterworth, D.4    Khan, A.5
  • 10
    • 0034027107 scopus 로고    scopus 로고
    • Endoglin is a suitable target for efficient imagingof solid tumors: in vivo evidence in a canine mammary carcinoma model
    • Fonsatti E, Jekunen AP, Kairemo KJ, Coral S, Snellman M, et al. (2000) Endoglin is a suitable target for efficient imagingof solid tumors: in vivo evidence in a canine mammary carcinoma model. ClinCancer Res 6: 2037-2043.
    • (2000) ClinCancer Res , vol.6 , pp. 2037-2043
    • Fonsatti, E.1    Jekunen, A.P.2    Kairemo, K.J.3    Coral, S.4    Snellman, M.5
  • 11
    • 79951704331 scopus 로고    scopus 로고
    • Multimodality molecular imaging ofCD105 (Endoglin) expression
    • Zhang Y, Yang Y, Hong H, Cai W, (2011) Multimodality molecular imaging ofCD105 (Endoglin) expression. Int J Clin Exp Med 4: 32-42.
    • (2011) Int J Clin Exp Med , vol.4 , pp. 32-42
    • Zhang, Y.1    Yang, Y.2    Hong, H.3    Cai, W.4
  • 12
    • 0033557520 scopus 로고    scopus 로고
    • Breastcarcinoma: vascular density determined using CD105 antibody correlateswith tumor prognosis
    • Kumar S, Ghellal A, Li C, Byrne G, Haboubi N, et al. (1999) Breastcarcinoma: vascular density determined using CD105 antibody correlateswith tumor prognosis. Cancer Res 59: 856-861.
    • (1999) Cancer Res , vol.59 , pp. 856-861
    • Kumar, S.1    Ghellal, A.2    Li, C.3    Byrne, G.4    Haboubi, N.5
  • 13
    • 33744739507 scopus 로고    scopus 로고
    • Endoglin (CD105) as a prognostic factor inhead and neck squamous cell carcinoma
    • Kyzas PA, Agnantis NJ, Stefanou D, (2006) Endoglin (CD105) as a prognostic factor inhead and neck squamous cell carcinoma. Virchows Archiv 448: 768-775.
    • (2006) Virchows Archiv , vol.448 , pp. 768-775
    • Kyzas, P.A.1    Agnantis, N.J.2    Stefanou, D.3
  • 14
    • 0035179614 scopus 로고    scopus 로고
    • Evaluationof angiogenesis in non-small cell lung cancer: comparison betweenanti-CD34 antibody and anti-CD105 antibody
    • Tanaka F, Otake Y, Yanagihara K, Kawano Y, Miyahara R, et al. (2001) Evaluationof angiogenesis in non-small cell lung cancer: comparison betweenanti-CD34 antibody and anti-CD105 antibody. ClinCancer Res 7: 3410-3415.
    • (2001) ClinCancer Res , vol.7 , pp. 3410-3415
    • Tanaka, F.1    Otake, Y.2    Yanagihara, K.3    Kawano, Y.4    Miyahara, R.5
  • 16
    • 0030932552 scopus 로고    scopus 로고
    • Invitro inhibition of endothelial cell growth by the antiangiogenic drug AGM-1470 (TNP-470)and the anti-endoglin antibody TEC-11
    • Maier JA, Delia D, Thorpe PE, Gasparini G, (1997) Invitro inhibition of endothelial cell growth by the antiangiogenic drug AGM-1470 (TNP-470)and the anti-endoglin antibody TEC-11. AnticancerDrugs 8: 238-244.
    • (1997) AnticancerDrugs , vol.8 , pp. 238-244
    • Maier, J.A.1    Delia, D.2    Thorpe, P.E.3    Gasparini, G.4
  • 17
    • 0346121353 scopus 로고    scopus 로고
    • Synergybetween anti-endoglin (CD105) monoclonal antibodies and TGF-betain suppression of growth of human endothelial cells
    • She X, Matsuno F, Harada N, Tsai H, Seon BK, (2004) Synergybetween anti-endoglin (CD105) monoclonal antibodies and TGF-betain suppression of growth of human endothelial cells. Int J Cancer 108: 251-257.
    • (2004) Int J Cancer , vol.108 , pp. 251-257
    • She, X.1    Matsuno, F.2    Harada, N.3    Tsai, H.4    Seon, B.K.5
  • 18
    • 0032971818 scopus 로고    scopus 로고
    • Inductionof lasting complete regression of preformed distinct solid tumors by targetingthe tumor vasculature using two new anti-endoglin monoclonal antibodies
    • Matsuno F, Haruta Y, Kondo M, Tsai H, Barcos M, et al. (1999) Inductionof lasting complete regression of preformed distinct solid tumors by targetingthe tumor vasculature using two new anti-endoglin monoclonal antibodies. ClinCancer Res 5: 371-382.
    • (1999) ClinCancer Res , vol.5 , pp. 371-382
    • Matsuno, F.1    Haruta, Y.2    Kondo, M.3    Tsai, H.4    Barcos, M.5
  • 19
    • 0030858765 scopus 로고    scopus 로고
    • Long-lastingcomplete inhibition of human solid tumors in SCID mice by targeting endothelialcells of tumor vasculature with antihuman endoglin immunotoxin
    • Seon BK, Matsuno F, Haruta Y, Kondo M, Barcos M, (1997) Long-lastingcomplete inhibition of human solid tumors in SCID mice by targeting endothelialcells of tumor vasculature with antihuman endoglin immunotoxin. ClinCancer Res 3: 1031-1044.
    • (1997) ClinCancer Res , vol.3 , pp. 1031-1044
    • Seon, B.K.1    Matsuno, F.2    Haruta, Y.3    Kondo, M.4    Barcos, M.5
  • 20
    • 0033609719 scopus 로고    scopus 로고
    • Antiangiogenicradioimmunotherapy of human solid tumors in SCID mice using (125)I-labeledanti-endoglin monoclonal antibodies
    • Tabata M, Kondo M, Haruta Y, Seon BK, (1999) Antiangiogenicradioimmunotherapy of human solid tumors in SCID mice using (125)I-labeledanti-endoglin monoclonal antibodies. Int J Cancer 82: 737-742.
    • (1999) Int J Cancer , vol.82 , pp. 737-742
    • Tabata, M.1    Kondo, M.2    Haruta, Y.3    Seon, B.K.4
  • 21
    • 0035503538 scopus 로고    scopus 로고
    • Antiangiogenictherapy of established tumors in human skin/severe combined immunodeficiencymouse chimeras by anti-endoglin (CD105) monoclonal antibodies,and synergy between anti-endoglin antibody and cyclophosphamide
    • Takahashi N, Haba A, Matsuno F, Seon BK, (2001) Antiangiogenictherapy of established tumors in human skin/severe combined immunodeficiencymouse chimeras by anti-endoglin (CD105) monoclonal antibodies,and synergy between anti-endoglin antibody and cyclophosphamide. CancerRes 61: 7846-7854.
    • (2001) CancerRes , vol.61 , pp. 7846-7854
    • Takahashi, N.1    Haba, A.2    Matsuno, F.3    Seon, B.K.4
  • 22
    • 42149083332 scopus 로고    scopus 로고
    • Anti-tumoractivity of an anti-endoglin monoclonal antibody is enhanced in immunocompetentmice
    • Tsujie M, Tsujie T, Toi H, Uneda S, Shiozaki K, et al. (2008) Anti-tumoractivity of an anti-endoglin monoclonal antibody is enhanced in immunocompetentmice. Int J Cancer 122: 2266-2273.
    • (2008) Int J Cancer , vol.122 , pp. 2266-2273
    • Tsujie, M.1    Tsujie, T.2    Toi, H.3    Uneda, S.4    Shiozaki, K.5
  • 23
    • 39049176805 scopus 로고    scopus 로고
    • Effectiveanti-angiogenic therapy of established tumors in mice by naked anti-humanendoglin (CD105) antibody: differences in growth rate andtherapeutic response between tumors growing at different sites
    • Tsujie M, Uneda S, Tsai H, Seon BK, (2006) Effectiveanti-angiogenic therapy of established tumors in mice by naked anti-humanendoglin (CD105) antibody: differences in growth rate andtherapeutic response between tumors growing at different sites. Int J Oncol 29: 1087-1094.
    • (2006) Int J Oncol , vol.29 , pp. 1087-1094
    • Tsujie, M.1    Uneda, S.2    Tsai, H.3    Seon, B.K.4
  • 24
    • 68249147445 scopus 로고    scopus 로고
    • Anti-endoglinmonoclonal antibodies are effective for suppressing metastasis and the primarytumors by targeting tumor vasculature
    • Uneda S, Toi H, Tsujie T, Tsujie M, Harada N, et al. (2009) Anti-endoglinmonoclonal antibodies are effective for suppressing metastasis and the primarytumors by targeting tumor vasculature. Int J Cancer 125: 1446-1453.
    • (2009) Int J Cancer , vol.125 , pp. 1446-1453
    • Uneda, S.1    Toi, H.2    Tsujie, T.3    Tsujie, M.4    Harada, N.5
  • 25
    • 8144230707 scopus 로고    scopus 로고
    • Endoglin promotes endothelial cell proliferation andTGF-beta/ALK1 signal transduction
    • Lebrin F, Goumans MJ, Jonker L, Carvalho RL, Valdimarsdottir G, et al. (2004) Endoglin promotes endothelial cell proliferation andTGF-beta/ALK1 signal transduction. EMBO J 23: 4018-4028.
    • (2004) EMBO J , vol.23 , pp. 4018-4028
    • Lebrin, F.1    Goumans, M.J.2    Jonker, L.3    Carvalho, R.L.4    Valdimarsdottir, G.5
  • 26
    • 0036215654 scopus 로고    scopus 로고
    • Effective gene transfer to solid tumors using different nonviralgene delivery techniques: electroporation, liposomes, and integrin-targetedvector
    • Cemazar M, Sersa G, Wilson J, Tozer GM, Hart SL, et al. (2002) Effective gene transfer to solid tumors using different nonviralgene delivery techniques: electroporation, liposomes, and integrin-targetedvector. Cancer Gene Ther 9: 399-406.
    • (2002) Cancer Gene Ther , vol.9 , pp. 399-406
    • Cemazar, M.1    Sersa, G.2    Wilson, J.3    Tozer, G.M.4    Hart, S.L.5
  • 27
    • 0038725471 scopus 로고    scopus 로고
    • CD105is important for angiogenesis: evidence and potential applications
    • Duff SE, Li C, Garland JM, Kumar S, (2003) CD105is important for angiogenesis: evidence and potential applications. FASEB J 17: 984-992.
    • (2003) FASEB J , vol.17 , pp. 984-992
    • Duff, S.E.1    Li, C.2    Garland, J.M.3    Kumar, S.4
  • 29
    • 70349497161 scopus 로고    scopus 로고
    • Theendothelial cell tube formation assay on basement membrane turns 20:state of the science and the art
    • Arnaoutova I, George J, Kleinman HK, Benton G, (2009) Theendothelial cell tube formation assay on basement membrane turns 20:state of the science and the art. Angiogenesis 12: 267-274.
    • (2009) Angiogenesis , vol.12 , pp. 267-274
    • Arnaoutova, I.1    George, J.2    Kleinman, H.K.3    Benton, G.4
  • 30
    • 0001421509 scopus 로고    scopus 로고
    • CD105antagonizes the inhibitory signaling of transforming growth factor beta1 onhuman vascular endothelial cells
    • Li C, Hampson IN, Hampson L, Kumar P, Bernabeu C, et al. (2000) CD105antagonizes the inhibitory signaling of transforming growth factor beta1 onhuman vascular endothelial cells. FASEB J 14: 55-64.
    • (2000) FASEB J , vol.14 , pp. 55-64
    • Li, C.1    Hampson, I.N.2    Hampson, L.3    Kumar, P.4    Bernabeu, C.5
  • 31
    • 33749827108 scopus 로고    scopus 로고
    • Electrically-assistednucleic acids delivery to tissues in vivo: where do we stand?
    • Cemazar M, Golzio M, Sersa G, Rols MP, Teissie J, (2006) Electrically-assistednucleic acids delivery to tissues in vivo: where do we stand? CurrPharm Des 12: 3817-3825.
    • (2006) CurrPharm Des , vol.12 , pp. 3817-3825
    • Cemazar, M.1    Golzio, M.2    Sersa, G.3    Rols, M.P.4    Teissie, J.5
  • 32
    • 70349339054 scopus 로고    scopus 로고
    • Targetedgene silencing into solid tumors with electrically mediated siRNA delivery
    • Golzio M, Mazzolini L, Paganin-Gioanni A, Teissie J, (2009) Targetedgene silencing into solid tumors with electrically mediated siRNA delivery. MethodsMol Biol 555: 15-27.
    • (2009) MethodsMol Biol , vol.555 , pp. 15-27
    • Golzio, M.1    Mazzolini, L.2    Paganin-Gioanni, A.3    Teissie, J.4
  • 33
    • 78650877069 scopus 로고    scopus 로고
    • Targetedgene-and-host progenitor cell therapy for nonunion bone fracturerepair
    • Kimelman-Bleich N, Pelled G, Zilberman Y, Kallai I, Mizrahi O, et al. (2011) Targetedgene-and-host progenitor cell therapy for nonunion bone fracturerepair. Mol Ther 19: 53-59.
    • (2011) Mol Ther , vol.19 , pp. 53-59
    • Kimelman-Bleich, N.1    Pelled, G.2    Zilberman, Y.3    Kallai, I.4    Mizrahi, O.5
  • 34
    • 58049200809 scopus 로고    scopus 로고
    • Phase I trial of interleukin-12 plasmid electroporationin patients with metastatic melanoma
    • Daud AI, DeConti RC, Andrews S, Urbas P, Riker AI, et al. (2008) Phase I trial of interleukin-12 plasmid electroporationin patients with metastatic melanoma. Journal of ClinicalOncology 26: 5896-5903.
    • (2008) Journal of ClinicalOncology , vol.26 , pp. 5896-5903
    • Daud, A.I.1    DeConti, R.C.2    Andrews, S.3    Urbas, P.4    Riker, A.I.5
  • 35
    • 80052922767 scopus 로고    scopus 로고
    • Electrochemotherapy:a new technological approach in treatment of metastases in the liver
    • Edhemovic I, Gadzijev EM, Brecelj E, Miklavcic D, Kos B, et al. (2011) Electrochemotherapy:a new technological approach in treatment of metastases in the liver. TechnolCancer Res Treat 10: 475-485.
    • (2011) TechnolCancer Res Treat , vol.10 , pp. 475-485
    • Edhemovic, I.1    Gadzijev, E.M.2    Brecelj, E.3    Miklavcic, D.4    Kos, B.5
  • 38
    • 34247141017 scopus 로고    scopus 로고
    • Invivo gene silencing in solid tumors by targeted electrically mediated siRNAdelivery
    • Golzio M, Mazzolini L, Ledoux A, Paganin A, Izard M, et al. (2007) Invivo gene silencing in solid tumors by targeted electrically mediated siRNAdelivery. Gene Ther 14: 752-759.
    • (2007) Gene Ther , vol.14 , pp. 752-759
    • Golzio, M.1    Mazzolini, L.2    Ledoux, A.3    Paganin, A.4    Izard, M.5
  • 39
    • 38349148685 scopus 로고    scopus 로고
    • Invivo silencing of a molecular target by short interfering RNA electroporation:tumor vascularization correlates to delivery efficiency
    • Takei Y, Nemoto T, Mu P, Fujishima T, Ishimoto T, et al. (2008) Invivo silencing of a molecular target by short interfering RNA electroporation:tumor vascularization correlates to delivery efficiency. MolCancer Ther 7: 211-221.
    • (2008) MolCancer Ther , vol.7 , pp. 211-221
    • Takei, Y.1    Nemoto, T.2    Mu, P.3    Fujishima, T.4    Ishimoto, T.5
  • 40
    • 84855207557 scopus 로고    scopus 로고
    • Examining the role of Rac1 in tumorangiogenesis and growth: a clinically relevant RNAi-mediatedapproach
    • Vader P, vander Meel R, Symons MH, Fens MH, Pieters E, et al. (2011) Examining the role of Rac1 in tumorangiogenesis and growth: a clinically relevant RNAi-mediatedapproach. Angiogenesis 14: 457-466.
    • (2011) Angiogenesis , vol.14 , pp. 457-466
    • Vader, P.1    vander Meel, R.2    Symons, M.H.3    Fens, M.H.4    Pieters, E.5
  • 41
    • 54249143980 scopus 로고    scopus 로고
    • Barriers to successful delivery of short interferingRNA after systemic administration
    • White PJ, (2008) Barriers to successful delivery of short interferingRNA after systemic administration. Clin Exp Pharmacol Physiol 35: 1371-1376.
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 1371-1376
    • White, P.J.1
  • 44
    • 0034894956 scopus 로고    scopus 로고
    • Involvementof p38 MAP kinase in TGF-beta-stimulated VEGF synthesis in aorticsmooth muscle cells
    • Yamamoto T, Kozawa O, Tanabe K, Akamatsu S, Matsuno H, et al. (2001) Involvementof p38 MAP kinase in TGF-beta-stimulated VEGF synthesis in aorticsmooth muscle cells. J Cell Biochem 82: 591-598.
    • (2001) J Cell Biochem , vol.82 , pp. 591-598
    • Yamamoto, T.1    Kozawa, O.2    Tanabe, K.3    Akamatsu, S.4    Matsuno, H.5
  • 45
    • 81755162307 scopus 로고    scopus 로고
    • Intracranialhemorrhage in patients treated with bevacizumab: report of two cases
    • Nishimura T, Furihata M, Kubo H, Tani M, Agawa S, et al. (2011) Intracranialhemorrhage in patients treated with bevacizumab: report of two cases. World J Gastroenterol 17: 4440-4444.
    • (2011) World J Gastroenterol , vol.17 , pp. 4440-4444
    • Nishimura, T.1    Furihata, M.2    Kubo, H.3    Tani, M.4    Agawa, S.5
  • 46
  • 47
  • 48
    • 77953912008 scopus 로고    scopus 로고
    • Smooth-muscle-likecells derived from human embryonic stem cells support and augment cord-likestructures in vitro
    • Vo E, Hanjaya-Putra D, Zha Y, Kusuma S, Gerecht S, (2010) Smooth-muscle-likecells derived from human embryonic stem cells support and augment cord-likestructures in vitro. Stem Cell Rev 6: 237-247.
    • (2010) Stem Cell Rev , vol.6 , pp. 237-247
    • Vo, E.1    Hanjaya-Putra, D.2    Zha, Y.3    Kusuma, S.4    Gerecht, S.5


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