How likely is environmental or patient cross-contamination of Chlamydia trachomatis DNA to lead to false positive results in patients attending our clinic?

Sexually Transmitted Infections

Volumn 89, Issue 2, 2013, Pages 105-107

  Chan, Sum Yee ^a   Jose, Sophie ^b   King, Rebecca ^a   Pakianathan, Mark R ^a   Sabin, Caroline ^b   Sadiq, S Tariq ^c   Hay, Phillip E ^a   Planche, Tim ^c  

^a ST GEORGE S HOSPITAL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ANALYSIS; ARTICLE; CHLAMYDIA TRACHOMATIS; CONTAMINATION; CROSS CONTAMINATION; FALSE POSITIVE RESULT; HUMAN; MAJOR CLINICAL STUDY; NONHUMAN; PATIENT THROUGHPUT ANALYSIS; POISSON DISTRIBUTION; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; URINALYSIS;

ADULT; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; CROSS INFECTION; DIAGNOSTIC ERRORS; DNA CONTAMINATION; ENVIRONMENTAL MICROBIOLOGY; FEMALE; HUMANS; MALE;

EID: 84874620672     PISSN: 13684973     EISSN: 14723263     Source Type: Journal    
DOI: 10.1136/sextrans-2012-050667     Document Type: Article

References (6)

1. Dube G, Phattey J, Brown L, et al. Hard surface contamination with Chlamydia and Gonorrhoea. Oral abstract 42. Second Joint Conference of the British HIV Association (BHIVA) with the British Association for Sexual Health and HIV (BASHH). HIV Medicine 11(Suppl 1);16.
2. Lewis N, Dube G, Carter C, et al. Chlamydia and gonorrhoea contamination of clinic surfaces. Sex Transm Infect Published Online First: 25 April 2012. doi:10.1136/sextrans-2012-050543
3. Meader E, Waters J, Sillis M. Chlamydia trachomatis RNA in the environment: is there potential for false-positive nucleic acid amplification test results? Sex Transm Infect 2008; 84:107-10.
4. Novak KD, Kowalski RP, Karenchak LM, et al. Chlamydia trachomatis can be transmitted by a nonporous plastic surface in vitro. Cornea 1995; 14:523-6.
5. Kramer A, Schwebke I, Kampf G. How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infect Dis 2006; 6:130.
6. Perez JL, Gomez E, Sauca G. Survival of gonococci from urethral discharge on fomites (letter). Eur Jr of Clin Microbiol Infect Dis 1990; 1:54-5.