The association of serum 25-hydroxyvitamin D and vertebral fractures in patients with type 2 diabetes

Endocrine Journal

Volumn 60, Issue 2, 2013, Pages 179-184

  Kim, Yoon Ji ^a   Park, Seok O ^b   Kim, Tae Ho ^a   Lee, Jae Hyuk ^a   Kim, Se Hwa ^a  

^a Kwandong University College of Medicine   (South Korea)

^b Sung Ae Hospital   (South Korea)

Author keywords

Diabetes; Osteoporosis; Vertebral fracture; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; POSTMENOPAUSE; PREVALENCE; SEX DIFFERENCE; SPINE FRACTURE; SPINE RADIOGRAPHY; THORACOLUMBAR SPINE; VITAMIN BLOOD LEVEL;

25-HYDROXYVITAMIN D 2; AGED; AGED, 80 AND OVER; CALCIFEDIOL; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; MALE; MIDDLE AGED; NUTRITIONAL STATUS; OSTEOPOROTIC FRACTURES; PREVALENCE; RECURRENCE; REPUBLIC OF KOREA; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SPINAL FRACTURES; VITAMIN D DEFICIENCY;

EID: 84874619301     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ12-0269     Document Type: Article

References (27)

1. Lips P (2001) Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 22:477-501.
2. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Dawson-Hughes B (2004) Positive association between 25-hy droxyvitamin D levels and bone mineral density: a population-based study of younger and older adults. Am J Med 116:634-639.
3. Visser M, Deeg DJH, Lips P (2003) Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam. J Clin Endocrinol Metab 88:5766-5772.
4. Pfeifer M, Begerow B, Minne HW, Schlotthauer T, Pospeschill M, et al. (2001) Vitamin D status, trunk muscle strength, body sway, falls and fractures among 237 postmenopausal women with osteoporosis. Exp Clin Endocrinol Diabetes 109:87-92.
5. Gerdhem P, Ringsberg KAM, Obrant KJ, Akesson K (2005) Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of elderly women. Osteoporos Int 16:1425-1431.
6. Van Schoor NM, Visser M, Pluijm SMF, Kuchuk N, Smit JH, et al. (2008) Vitamin D deficiency as a risk factor for osteoporotic fractures. Bone 42:260-266.
7. Looker AC, Mussolino ME (2008) Serum 25-hydroxyvitamin D and hip fracture risk in older US white adults. J Bone Miner Res 23:143-150.
8. Cauley JA, Parimi N, Ensrud KE, Bauer DC, Cawthon PM, et al. (2010) Serum 25-hydroxyvitamin D and the risk of hip and nonspine fractures in older men. J Bone Miner Res 25:545-553.
9. Nakamura K, Saito T, Oyama M, Oshiki R, Kobayashi R, et al. (2011) Vitamin D sufficiency is associated with low incidence of limb and vertebral fractures in community-dwelling elderly Japanese women: the Muramatsu Study. Osteoporos Int 22:97-103.
10. Garnero P, Munoz F, Sornay-Rendu E, Delmas PD (2007) Associations of vitamin D status with bone mineral density, bone turnover, bone loss and fracture risk in healthy postmenopausal women. The OFELY study. Bone 40:716-722.
11. Roddam AW, Neale R, Appleby P, Allen NE, Tipper S, et al. (2007) Association between plasma 25-hydroxyvitamin D levels and fracture risk: the EPIC-Oxford study. Am J Epidemiol 166:1327-1336.
12. Inzerillo AM, Epstein S (2004) Osteoporosis and diabetes mellitus. Rev Endocr Metab Disord 5:261-268.
13. Vestergaard P (2007) Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes-a meta-analysis. Osteoporos Int 18:427-444.
14. De Liefde II, van Klift M, de Laet CE, van Daele PL, Hofman A, et al. (2005) Bone mineral density and fracture risk in type 2 diabetes mellitus: The Rotterdam Study. Osteoporos Int 16:1713-1720.
15. Schwartz AV, Garnero P, Hillier TA, Sellmeyer DE, Strotmeyer ES, et al. (2009) Pentosidine and increased fracture risk in older adults with type 2 diabetes. J Clin Endocrinol Metab 94:2380-2386.
16. Schwartz AV, Hillier TA, Sellmeyer DE, Resnick HE, Gregg E, et al. (2002) Older women with diabetes have a higher risk of falls; A prospective study. Diabetes Care 25:1749-1754.
17. Genant HK, Wu CY, Van Kuijk C, Nevitt M (1993) Vertebral fracture assessment using a SQ technique. J Bone Miner Res 8:1137-1148.
18. Bischoff-Ferrari HA, Dietrich T, Orav EJ, Hu FB, Zhang YQ, et al. (2004) Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged ≥ 60 y. Am J Clin Nutr 80:752-758.
19. Bischoff-Ferrari HA, Orav EJ, Dawson-Hughes B (2006) Effect of cholecalciferol plus calcium on falling in ambulatory older men and women-a 3-year randomized controlled trial. Arch Intern Med 166:424-430.
20. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, et al. (2004) Effect of vitamin D on falls: a meta-analysis. JAMA 291:1999-2006.
21. Mezquita-Raya P, Munoz-Torres M, Luna JD, Luna V, Lopez-Rodriguez F, et al. (2001) Relation between vitamin D insufficiency, bone density, and bone metabolism in healthy postmenopausal women. J Bone Miner Res 16:1408-1415.
22. Cauley JA, Lacroix AZ, Wu L, Horwitz M, Danielson ME, et al. (2008) Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med 149:242-250.
23. McNair P, Madsbad S, Christensen MS, Christiansen C, Faber OK, et al. (1979) Bone mineral loss in insulintreated diabetes mellitus: Studies on pathogenesis. Acta Endocrinol (Copenh) 90:463-472.
24. McNair P, Christensen MS, Madsbad S, Christiansen C, Transbol I (1981) Hypoparathyroidism in diabetes mellitus. Acta Endocrinol (Copenh) 96:81-86.
25. Watts NB, Bilezikian JP, Camacho PM, Greenspan SL, Harris ST, et al. (2010) American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the diagnosis and treatment of postmenopausal osteoporosis. Endocr Pract 16 Suppl 3:1-37.
26. Porthouse J, Cockayne S, King C, Porthouse J, Cockayne S, et al. (2005) Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. BMJ 330:1003-1008.
27. Choi HS, Oh HJ, Choi H, Choi WH, Kim JG, et al. (2011) Vitamin D insufficiency in Korea-A greater threat to younger generation: The Korea National Health and Nutrition Examination Survey (KNHANES) 2008. J Clin Endocrinol Metab 96:643-651.