Novel biomarkers of hyperlipidemic acute pancreatitis: Metabolomic identification

Asian Biomedicine

Volumn 6, Issue 5, 2012, Pages 765-769

  Zhao, Yan ^a   Jia, Wei ^b   Su, Mingming ^a   Qiu, Yunping ^c   Wang, Xingpeng ^a  

^a TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c Shanghai Jiao Tong University   (China)

Author keywords

Blood; Hyperlipidemic pancreatitis; Metabolism; Urine

Indexed keywords

16 HEXADECANOIC ACID; 18 OCTADECANOIC ACID; 4 HYDROXYPHENYLACETIC ACID; 4 HYDROXYPHENYLPOPIONIC ACID; ACONITIC ACID; BIOLOGICAL MARKER; CITRIC ACID; HIPPURIC ACID; TRYPTOPHAN; TYRAMINE; TYROSINE; UNCLASSIFIED DRUG;

ACUTE PANCREATITIS; ADULT; AMINO ACID METABOLISM; ARTICLE; BLOOD; CLINICAL ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; FATTY ACID METABOLISM; FEMALE; GAS CHROMATOGRAPHY; HUMAN; HYPERLIPIDEMIA; INTESTINE FLORA; MALE; MASS SPECTROMETRY; METABOLOMICS; MICROBIAL METABOLISM; URINE;

EID: 84874610222     PISSN: 19057415     EISSN: 1875855X     Source Type: Journal    
DOI: 10.5372/1905-7415.0605.119     Document Type: Article

References (18)

1. Yadav D, Pitchumoni CS. Issues in hyperlipidemic pancreatitis. J Pancreas. 2008; 9:664-5.
2. Hood L, Perlmutter RM. The impact of systems approaches on biological problems in drug discovery. Nat Biotechnol. 2004; 22:1215-7.
3. Hwang D, Rust AG, Ramsey S, Smith JJ, Leslie DM, Weston AD, et al. A data integration methodology for systems biology. Proc Natl Acad Sci. 2005; 102: 17296-301.
4. Nicholson JK, Holmes E, Wilson ID. Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol. 2005; 3:431-8.
5. Branch Association for Diseases of Digestive System, Chinese Medical Association. Draft criteria for diagnosis and treatment of acute pancreatitis in China (in Chinese). Zhonghua Neike Zazhi. 2004; 43:236-8.
6. Balthazar EJ, Robinson DL, Megibow AJ, Ranson JH. Acute pancreatitis: value of CT in establishing prognosis. Radiology. 1990; 174:331-6.
7. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med.1985;13:818-29.
8. Qiu Y, Su M, Liu Y, Chen M, Gu J, Zhang J, et al. Application of ethyl chloroformate derivatization for gas chromatography-mass spectrometry based metabonomic profiling. Anal Chim Acta. 2007; 583: 277-83.
9. Trygg J, Gullberg J, Johansson AI, Jonsson P, Antti H, Marklund SL, et al. Extraction and GC/MS analysis of the human blood plasma metabolome. Anal Chem. 2005; 77: 8086-94.
10. Wang X, Su M, Qiu Y, Ni Y, Zhao T, Zhou M, et al. Metabolic regulatory network alterations in response to acute cold stress and ginsenoside intervention. J Proteome Res. 2007; 6: 3449-55.
11. Andersson R, Wang XD, Sun ZW, Deng XM, Soltesz V, Ihse I. Effect of a platelet-activating factor antagonist on pancreatitis-associated gut barrier dysfunction in rats. Pancreas. 1998; 17:107-19.
12. Wang XD, Sun ZW, Borjesson A, Andersson R. Inhibition of platelet-activating factor, intercellular adhesion molecule 1 and platelet endothelial cell adhesion molecule 1 reduces experimental pancreatitisassociated gut endothelial barrier dysfunction. Br J Surg. 1999; 86:411-6.
13. Ammori BJ, Leeder PC, King RF, Barclay GR, Martin IG, Larvin M, et al. Early increase in intestinal permeability in patients with severe acute pancreatitis: correlation with endotoxemia, organ failure, and mortality. J Gastrointest Surg. 1999; 3:252-62.
14. Juvonen PO, Alhava EM, Takala JA. Gut permeability in patients with acute pancreatitis. Scand J Gastroenterol. 2000; 35: 1314-8.
15. Jennifer S Carew, Peng Huang. Mitochondrial defects in cancer. Mol Cancer. 2002; 1:9.
16. Mark P, Mattson, Marc Gleichmann, Cheng A. Mitochondria in neuroplasticity and neurologica disorders. Neuron. 2008; 60:748-66.
17. Halestrap AP, Clarke SJ, Khaliulin I. The role of mitochondria in protection of the heart by preconditioning. Biochim Biophys Acta. 2007; 1767: 1007-31.
18. Havel RJ. Pathogenesis, differentiation and management of hypertriglyceridemia. Adv Intern Med. 1969; 15:117-54.