Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr- SO§ssub§3§esub§H) and their docking and urease inhibitory activity

DARU, Journal of Pharmaceutical Sciences

Volumn 21, Issue 1, 2013, Pages

  Ziarani, Ghodsi Mohammadi ^a   Faramarzi, Sakineh ^a   Asadi, Shima ^a   Badiei, Alireza ^b   Bazl, Roya ^c   Amanlou, Massoud ^c  

^a ALZAHRA UNIVERSITY   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Barbituric acid; Multicomponent reaction (MCRs); Pyrano 2,3 d pyrimidine diones; SBA Pr SOH; Urease inhibitory

Indexed keywords

7 AMINO 6 CYANO 1,3 DIMETHYL 5 (4 HYDROXYPHENYL)1,5 DIHYDROPYRANO[2,3 D]PYRIMIDINE 2,4 DIONE; 7 AMINO 6 CYANO 5 (2,6 DICHLOROPHENYL) 5H PYRANO[2,3 D]PYRIMIDINONE; 7 AMINO 6 CYANO 5 (3 METHOXYLPHENYL) 5H PYRANO[2,3 D]PYRIMIDINE 2,4(1H,3H) DIONE DERIVATIVE; 7 AMINO 6 CYANO 5 (3 METHYLPHENYL) 5H PYRANO[2,3 D]PYRIMIDINE 2,4(1H,3H) DIONE DERIVATIVE; BARBITURIC ACID; METHYL GROUP; PHENOLSULFONPHTHALEIN; PYRANO[2,3 D]PYRIMIDINE DIONE DERIVATIVE; SILICON DIOXIDE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; UREASE;

ARTICLE; CATALYST; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG HYDROLYSIS; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; HYDROPHOBICITY; MASS FRAGMENTOGRAPHY; MOLECULAR DOCKING; POROSITY;

EID: 84874600334     PISSN: 15608115     EISSN: 20082231     Source Type: Journal    
DOI: 10.1186/2008-2231-21-3     Document Type: Article

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