Crucial Role of Hyaluronan in Neointimal Formation after Vascular Injury

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Kashima, Yuichiro ^a   Takahashi, Masafumi ^a,b   Shiba, Yuji ^a   Itano, Naoki ^c   Izawa, Atsushi ^a   Koyama, Jun ^a   Nakayama, Jun ^a   Taniguchi, Shun'ichiro ^a   Kimata, Koji ^d   Ikeda, Uichi ^a  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c KYOTO SANGYO UNIVERSITY   (Japan)

^d AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HERMES ANTIGEN; HYALURONIC ACID; HYALURONIDASE; MITOGEN ACTIVATED PROTEIN KINASE 3; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL INJURY; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CELL ACTIVATION; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE; GENE OVEREXPRESSION; HAS2 GENE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOUSE; NEOINTIMA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANALYSIS OF VARIANCE; ANIMALS; ATHEROSCLEROSIS; BLOTTING, WESTERN; BROMODEOXYURIDINE; CELL MOVEMENT; CELL PROLIFERATION; CYTOKINES; DNA PRIMERS; HUMANS; HYALURONIC ACID; HYMECROMONE; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MUSCLE, SMOOTH, VASCULAR; NEOINTIMA; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASCULAR SYSTEM INJURIES;

EID: 84874592439     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058760     Document Type: Article

References (33)

1. Curcio A, Torella D, Indolfi C, (2011) Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: approach to therapy. Circ J. 75: 1287-96.
2. Wight TN, (2008) Arterial remodeling in vascular disease: a key role for hyaluronan and versican. Front Biosci. 13: 4933-7.
3. Itano N, Sawai T, Yoshida M, Lenas P, Yamada Y, et al. (1999) Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem. 274: 25085-92.
4. Jiang D, Liang J, Noble PW, (2011) Hyaluronan as an immune regulator in human diseases. Physiol Rev. 91: 221-64.
5. Stern R, Asari AA, Sugahara KN, (2006) Hyaluronan fragments: an information-rich system. Eur J Cell Biol. 85: 699-715.
6. Chai S, Chai Q, Danielsen CC, Hjorth P, Nyengaard JR, et al. (2005) Overexpression of hyaluronan in the tunica media promotes the development of atherosclerosis. Circ Res. 96: 583-91.
7. Nagy N, Freudenberger T, Melchior-Becker A, Rock K, Ter Braak M, et al. (2010) Inhibition of hyaluronan synthesis accelerates murine atherosclerosis: novel insights into the role of hyaluronan synthesis. Circulation. 122: 2313-22.
8. Riessen R, Wight TN, Pastore C, Henley C, Isner JM, (1996) Distribution of hyaluronan during extracellular matrix remodeling in human restenotic arteries and balloon-injured rat carotid arteries. Circulation. 93: 1141-7.
9. Koyama H, Hibi T, Isogai Z, Yoneda M, Fujimori M, et al. (2007) Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M. Am J Pathol. 170: 1086-99.
10. Koyama H, Kobayashi N, Harada M, Takeoka M, Kawai Y, et al. (2008) Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis: pivotal role of a hyaluronan-rich tumor microenvironment. Am J Pathol. 172: 179-93.
11. Holtwick R, Gotthardt M, Skryabin B, Steinmetz M, Potthast R, et al. (2002) Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure. Proc Natl Acad Sci U S A. 99: 7142-7.
12. Miano JM, Ramanan N, Georger MA, de Mesy Bentley KL, Emerson RL, et al. (2004) Restricted inactivation of serum response factor to the cardiovascular system. Proc Natl Acad Sci U S A. 101: 17132-7.
13. Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, et al. (2008) Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice. Circulation. 117: 3079-87.
14. Sata M, Maejima Y, Adachi F, Fukino K, Saiura A, et al. (2000) A mouse model of vascular injury that induces rapid onset of medial cell apoptosis followed by reproducible neointimal hyperplasia. J Mol Cell Cardiol. 32: 2097-104.
15. Tanaka K, Sata M, Hirata Y, Nagai R, (2003) Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries. Circ Res. 93: 783-90.
16. Shiba Y, Takahashi M, Yoshioka T, Yajima N, Morimoto H, et al. (2007) M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system. Arterioscler Thromb Vasc Biol. 27: 283-9.
17. Yokouchi K, Numaguchi Y, Kubota R, Ishii M, Imai H, et al. (2006) l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Arterioscler Thromb Vasc Biol. 26: 2231-7.
18. Kolodgie FD, Burke AP, Farb A, Weber DK, Kutys R, et al. (2002) Differential accumulation of proteoglycans and hyaluronan in culprit lesions: insights into plaque erosion. Arterioscler Thromb Vasc Biol. 22: 1642-8.
19. Yoshioka T, Takahashi M, Shiba Y, Suzuki C, Morimoto H, et al. (2006) Granulocyte colony-stimulating factor (G-CSF) accelerates reendothelialization and reduces neointimal formation after vascular injury in mice. Cardiovasc Res. 70: 61-9.
20. Yoshihara S, Kon A, Kudo D, Nakazawa H, Kakizaki I, et al. (2005) A hyaluronan synthase suppressor, 4-methylumbelliferone, inhibits liver metastasis of melanoma cells. FEBS Lett. 579: 2722-6.
21. Nakamura T, Takagaki K, Shibata S, Tanaka K, Higuchi T, et al. (1995) Hyaluronic-acid-deficient extracellular matrix induced by addition of 4-methylumbelliferone to the medium of cultured human skin fibroblasts. Biochem Biophys Res Commun. 208: 470-5.
22. Fischer JW, Schror K, (2007) Regulation of hyaluronan synthesis by vasodilatory prostaglandins. Implications for atherosclerosis. Thromb Haemost. 98: 287-95.
23. Zhao L, Lee E, Zukas AM, Middleton MK, Kinder M, et al. (2008) CD44 expressed on both bone marrow-derived and non-bone marrow-derived cells promotes atherogenesis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol. 28: 1283-9.
24. Davis C, Fischer J, Ley K, Sarembock IJ, (2003) The role of inflammation in vascular injury and repair. J Thromb Haemost. 1: 1699-709.
25. Cuff CA, Kothapalli D, Azonobi I, Chun S, Zhang Y, et al. (2001) The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation. J Clin Invest. 108: 1031-40.
26. Savani RC, Wang C, Yang B, Zhang S, Kinsella MG, et al. (1995) Migration of bovine aortic smooth muscle cells after wounding injury. The role of hyaluronan and RHAMM. J Clin Invest. 95: 1158-68.
27. Goueffic Y, Guilluy C, Guerin P, Patra P, Pacaud P, et al. (2006) Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation. Cardiovasc Res. 72: 339-48.
28. Jain M, He Q, Lee WS, Kashiki S, Foster LC, et al. (1996) Role of CD44 in the reaction of vascular smooth muscle cells to arterial wall injury. J Clin Invest. 98: 877.
29. Kakizaki I, Kojima K, Takagaki K, Endo M, Kannagi R, et al. (2004) A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone. J Biol Chem. 279: 33281-9.
30. Vigetti D, Rizzi M, Viola M, Karousou E, Genasetti A, et al. (2009) The effects of 4-methylumbelliferone on hyaluronan synthesis, MMP2 activity, proliferation, and motility of human aortic smooth muscle cells. Glycobiology. 19: 537-46.
31. Murayama H, Takahashi M, Takamoto M, Shiba Y, Ise H, et al. (2008) Deficiency of tumour necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury. Cardiovasc Res. 80: 175-80.
32. Stacchino C, Spano R, Pettiti A, (1983) Spasmolytic activity of some 4-methylumbelliferone derivatives. Boll Chim Farm. 122: 158-60.
33. Fontaine L, Grand M, Molho D, Chabert MJ, Boschetti E, (1968) [Choleretic, spasmolytic and general pharmacologic activities of 4-methylumbelliferone]. Therapie. 23: 51-62.