When can R-CHOP not be used in an elderly patient?

ONCOLOGY (United States)

Volumn 27, Issue 2, 2013, Pages

  Coiffier, Bertrand ^a,b  

^a HOSPICES CIVILS DE LYON   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BENDAMUSTINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE; PREDNISONE; RITUXIMAB; VINCRISTINE SULFATE;

ALBUMIN BLOOD LEVEL; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CANCER RECURRENCE; COMORBIDITY; GERIATRIC ASSESSMENT; GERIATRIC CARE; HIGH RISK PATIENT; HUMAN; LARGE CELL LYMPHOMA; NOTE; QUALITY OF LIFE; TREATMENT OUTCOME; TREATMENT RESPONSE;

EID: 84874592009     PISSN: 08909091     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (7)

1. Sarkozy C, Coiffier B. Diffuse large B-cell lymphoma in the elderly: a review of potential difficulties. Clin Cancer Res. 2013; in press.
2. Peyrade F, Gastaud L, Re D, et al. Treatment decisions for elderly patients with haematological malignancies: a dilemma. Lancet Oncol. 2012;13:e344-52.
3. Thieblemont C, Grossoeuvre A, Houot R, et al. Non-Hodgkins lymphoma in very elderly patients over 80 years. A descriptive analysis of clinical presentation and outcome. Ann Oncol. 2008;19:774-9.
4. Thieblemont C, Coiffier B. Lymphoma in older patients. J Clin Oncol. 2007;25:1916-23.
5. Coiffier B, Thieblemont C, Van Den Neste E, et al. Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe dEtudes des Lymphomes de lAdulte. Blood. 2010;116:2040-5.
6. Peyrade F, Jardin F, Thieblemont C, et al. Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2011;12:460-8.
7. Hasselblom S, Stenson M, Werlenius O, et al. Improved outcome for very elderly patients with diffuse large B-cell lymphoma in the immunochemotherapy era. Leuk Lymphoma. 2012;53:394-9.