Gas2l3, a Novel Constriction Site-Associated Protein Whose Regulation Is Mediated by the APC/CCdh1 Complex

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Pe'er, Tal ^a   Lahmi, Roxane ^a   Sharaby, Yaara ^a   Chorni, Evelin ^a   Noach, Meirav ^a   Vecsler, Manuela ^a   Zlotorynski, Eitan ^a   Steen, Hanno ^b,c   Steen, Judith A ^b   Tzur, Amit ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN 20; CELL PROTEIN; CYCLIN A2; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; GEMININ; GROWTH ARREST SPECIFIC 2 LIKE PROTEIN 3; SECURIN; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; CYTOKINESIS; MITOSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; UPREGULATION; WESTERN BLOTTING;

ACTINS; AMINO ACID SEQUENCE; ANIMALS; CADHERINS; CELL CYCLE; HUMANS; MICROFILAMENT PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR SEQUENCE DATA; TUBULIN; XENOPUS LAEVIS;

EID: 84874578828     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057532     Document Type: Article

References (33)

1. Peters JM, (2006) The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 7: 644-656.
2. Taylor S, Peters JM, (2008) Polo and Aurora kinases: lessons derived from chemical biology. Curr Opin Cell Biol 20: 77-84.
3. Eggert US, Mitchison TJ, Field CM, (2006) Animal cytokinesis: from parts list to mechanisms. Annu Rev Biochem 75: 543-566.
4. Lindon C, Pines J, (2004) Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells. J Cell Biol 164: 233-241.
5. Zhao WM, Fang G, (2005) Anillin is a substrate of anaphase-promoting complex/cyclosome (APC/C) that controls spatial contractility of myosin during late cytokinesis. J Biol Chem 280: 33516-33524.
6. Bastos RN, Barr FA, (2010) Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission. J Cell Biol 191: 751-760.
7. Raiborg C, Stenmark H, (2011) Cell biology. A helix for the final cut. Science 331: 1533-1534.
8. Elia N, Sougrat R, Spurlin TA, Hurley JH, Lippincott-Schwartz J, (2011) Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission. Proc Natl Acad Sci U S A 108: 4846-4851.
9. Guizetti J, Schermelleh L, Mantler J, Maar S, Poser I, et al. (2011) Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments. Science 331: 1616-1620.
10. Hu CK, Coughlin M, Mitchison TJ, (2012) Midbody assembly and its regulation during cytokinesis. Mol Biol Cell 23: 1024-1034.
11. Sharp DJ, Ross JL, (2012) Microtubule-severing enzymes at the cutting edge. J Cell Sci 125: 2561-2569.
12. Brown NH, (2008) Spectraplakins: the cytoskeleton's Swiss army knife. Cell 135: 16-18.
13. Stroud MJ, Kammerer RA, Ballestrem C, (2011) Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins. J Biol Chem 286: 24987-24995.
14. Goriounov D, Leung CL, Liem RK, (2003) Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules. J Cell Sci 116: 1045-1058.
15. Brancolini C, Bottega S, Schneider C, (1992) Gas2, a growth arrest-specific protein, is a component of the microfilament network system. J Cell Biol 117: 1251-1261.
16. Schneider C, King RM, Philipson L, (1988) Genes specifically expressed at growth arrest of mammalian cells. Cell 54: 787-793.
17. Zhang T, Dayanandan B, Rouiller I, Lawrence EJ, Mandato CA, (2011) Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos. PLoS One 6: e24698.
18. Lee KK, Tang MK, Yew DT, Chow PH, Yee SP, et al. (1999) gas2 is a multifunctional gene involved in the regulation of apoptosis and chondrogenesis in the developing mouse limb. Dev Biol 207: 14-25.
19. Wolter P, Schmitt K, Fackler M, Kremling H, Probst L, et al. (2012) GAS2L3, a target gene of the DREAM complex, is required for proper cytokinesis and genomic stability. J Cell Sci 125: 2393-2406.
20. Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, et al. (2006) Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A 103: 3304-3309.
21. Rape M, Kirschner MW, (2004) Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry. Nature 432: 588-595.
22. Wu T, Merbl Y, Huo Y, Gallop JL, Tzur A, et al. (2010) UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex. Proc Natl Acad Sci U S A 107: 1355-1360.
23. McGarry TJ, Kirschner MW, (1998) Geminin, an inhibitor of DNA replication, is degraded during mitosis. Cell 93: 1043-1053.
24. Ayad NG, Rankin S, Murakami M, Jebanathirajah J, Gygi S, et al. (2003) Tome-1, a trigger of mitotic entry, is degraded during G1 via the APC. Cell 113: 101-113.
25. Zur A, Brandeis M, (2002) Timing of APC/C substrate degradation is determined by fzy/fzr specificity of destruction boxes. Embo J 21: 4500-4510.
26. Lorca T, Castro A, Martinez AM, Vigneron S, Morin N, et al. (1998) Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts. Embo J 17: 3565-3575.
27. Rankin S, Ayad NG, Kirschner MW, (2005) Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates. Mol Cell 18: 185-200.
28. Holt LJ, Krutchinsky AN, Morgan DO, (2008) Positive feedback sharpens the anaphase switch. Nature 454: 353-357.
29. Zou H, McGarry TJ, Bernal T, Kirschner MW, (1999) Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis. Science 285: 418-422.
30. Zur A, Brandeis M, (2001) Securin degradation is mediated by fzy and fzr, and is required for complete chromatid separation but not for cytokinesis. EMBO J 20: 792-801.
31. Ferrell JE Jr, (2000) What do scaffold proteins really do? Sci STKE 2000: pe1.
32. Lui C, Mills K, Brocardo MG, Sharma M, Henderson BR, (2012) APC as a mobile scaffold: regulation and function at the nucleus, centrosomes, and mitochondria. IUBMB Life 64: 209-214.
33. Roper K, Gregory SL, Brown NH, (2002) The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. J Cell Sci 115: 4215-4225.