HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

Journal of Experimental Medicine

Volumn 210, Issue 2, 2013, Pages 339-353

  Gautier, Emmanuel L ^a   Westerterp, Marit ^b,c   Bhagwat, Neha ^d,e   Cremers, Serge ^b   Shih, Alan ^d,e   Abdel Wahab, Omar ^d,e   Lütjohann, Dieter ^f   Randolph, Gwendalyn J ^a   Levine, Ross L ^d,e   Tall, Alan R ^b   Yvan Charvet, Laurent ^b,g  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d Human Oncology and Pathogenesis Program   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f UNIVERSITY HOSPITAL BONN   (Germany)

^g CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; APOLIPOPROTEIN A1; GLUCOSE; GLUCOSE TRANSPORTER 1; HIGH DENSITY LIPOPROTEIN; SHORT HAIRPIN RNA;

ALLELE; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL PROLIFERATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; FEEDING; GLUCOSE METABOLISM; GLUCOSE OXIDATION; HYPERMETABOLISM; IN VIVO STUDY; LEUKEMIA; LIPID STORAGE; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE; WASTING SYNDROME;

ADIPOSE TISSUE; ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BONE MARROW TRANSPLANTATION; DISEASE MODELS, ANIMAL; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HUMANS; INSULIN RESISTANCE; INTERLEUKIN-3; LEUKOCYTES; LIPOPROTEINS; LIPOPROTEINS, HDL; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOPROLIFERATIVE DISORDERS; OXIDATIVE PHOSPHORYLATION; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84874568275     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121357     Document Type: Article

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