메뉴 건너뛰기




Volumn 24, Issue 3, 2013, Pages 693-701

A clinical-biological risk stratification model for resected gastric cancer: Prognostic impact of HER2, FHIT, AND APC expression status

Author keywords

Apc; Fhit; Gastric cancer; Her2; Prognosis; Score

Indexed keywords

APC PROTEIN; BETA CATENIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE 2A; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FRAGILE HISTIDINE TRIAD PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 84874560562     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mds506     Document Type: Article
Times cited : (53)

References (55)
  • 2
    • 73649128552 scopus 로고    scopus 로고
    • Cell cycle regulators, APC/beta-catenin, NFkappaB and Epstein-Barr virus in gastric carcinomas
    • Kim B, Byun SJ, Kim YA et al.. Cell cycle regulators, APC/beta-catenin, NFkappaB and Epstein-Barr virus in gastric carcinomas. Pathology 2011; 42: 58-65.
    • (2011) Pathology , vol.42 , pp. 58-65
    • Kim, B.1    Byun, S.J.2    Kim, Y.A.3
  • 3
    • 80053589765 scopus 로고    scopus 로고
    • Prognostic impact of microscopic positive margin in gastric cancer patients
    • Nagata T, Ichikawa D, Komatsu S et al.. Prognostic impact of microscopic positive margin in gastric cancer patients. J Surg Oncol 2011; 104: 592-597.
    • (2011) J Surg Oncol , vol.104 , pp. 592-597
    • Nagata, T.1    Ichikawa, D.2    Komatsu, S.3
  • 4
    • 77649159783 scopus 로고    scopus 로고
    • Prognostic value of preoperative clinical staging assessed by computed tomography in resectable gastric cancer patients: a viewpoint in the era of preoperative treatment
    • Park SR, Kim MJ, Ryu KW et al.. Prognostic value of preoperative clinical staging assessed by computed tomography in resectable gastric cancer patients: a viewpoint in the era of preoperative treatment. Ann Surg 2011; 251: 428-435.
    • (2011) Ann Surg , vol.251 , pp. 428-435
    • Park, S.R.1    Kim, M.J.2    Ryu, K.W.3
  • 5
    • 80051647503 scopus 로고    scopus 로고
    • Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome
    • Begnami MD, Fukuda E, Fregnani JH et al.. Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome. J Clin Oncol 2011; 29: 3030-3036.
    • (2011) J Clin Oncol , vol.29 , pp. 3030-3036
    • Begnami, M.D.1    Fukuda, E.2    Fregnani, J.H.3
  • 6
    • 50849123421 scopus 로고    scopus 로고
    • HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
    • Gravalos C, Jimeno A. HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol 2008; 19: 1523-1529.
    • (2008) Ann Oncol , vol.19 , pp. 1523-1529
    • Gravalos, C.1    Jimeno, A.2
  • 7
    • 28244470074 scopus 로고    scopus 로고
    • Loss of Fhit expression is associated with poorer survival in gastric cancer but is not an independent prognostic marker
    • Bragantini E, Barbi S, Beghelli S et al.. Loss of Fhit expression is associated with poorer survival in gastric cancer but is not an independent prognostic marker. J Cancer Res Clin Oncol 2006; 132: 45-50.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 45-50
    • Bragantini, E.1    Barbi, S.2    Beghelli, S.3
  • 8
    • 0033961251 scopus 로고    scopus 로고
    • Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival
    • Capuzzi D, Santoro E, Hauck WW et al.. Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival. Cancer 2000; 88: 24-34.
    • (2000) Cancer , vol.88 , pp. 24-34
    • Capuzzi, D.1    Santoro, E.2    Hauck, W.W.3
  • 9
    • 0037314656 scopus 로고    scopus 로고
    • Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer
    • Rocco A, Schandl L, Chen J et al.. Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer. J Cancer Res Clin Oncol 2003; 129: 84-88.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 84-88
    • Rocco, A.1    Schandl, L.2    Chen, J.3
  • 10
    • 33644998539 scopus 로고    scopus 로고
    • Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers
    • Beghelli S, de Manzoni G, Barbi S et al.. Microsatellite instability in gastric cancer is associated with better prognosis in only stage II cancers. Surgery 2006; 139: 347-356.
    • (2006) Surgery , vol.139 , pp. 347-356
    • Beghelli, S.1    de Manzoni, G.2    Barbi, S.3
  • 11
    • 3242755102 scopus 로고    scopus 로고
    • Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches
    • Scartozzi M, Galizia E, Freddari F et al.. Molecular biology of sporadic gastric cancer: prognostic indicators and novel therapeutic approaches. Cancer Treat Rev 2004; 30: 451-459.
    • (2004) Cancer Treat Rev , vol.30 , pp. 451-459
    • Scartozzi, M.1    Galizia, E.2    Freddari, F.3
  • 12
    • 0032732728 scopus 로고    scopus 로고
    • Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer
    • Ramesh S, Nash J, McCulloch PG. Reduction in membranous expression of beta-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer. Br J Cancer 1999; 81: 1392-1397.
    • (1999) Br J Cancer , vol.81 , pp. 1392-1397
    • Ramesh, S.1    Nash, J.2    McCulloch, P.G.3
  • 13
    • 0036900195 scopus 로고    scopus 로고
    • Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival
    • Zhou YN, Xu CP, Han B et al.. Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survival. World J Gastroenterol 2002; 8: 987-993.
    • (2002) World J Gastroenterol , vol.8 , pp. 987-993
    • Zhou, Y.N.1    Xu, C.P.2    Han, B.3
  • 14
    • 33845437420 scopus 로고    scopus 로고
    • Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer
    • Mattioli E, Vogiatzi P, Sun A et al.. Immunohistochemical analysis of pRb2/p130, VEGF, EZH2, p53, p16(INK4A), p27(KIP1), p21(WAF1), Ki-67 expression patterns in gastric cancer. J Cell Physiol 2007; 210: 183-191.
    • (2007) J Cell Physiol , vol.210 , pp. 183-191
    • Mattioli, E.1    Vogiatzi, P.2    Sun, A.3
  • 15
    • 1842844370 scopus 로고    scopus 로고
    • Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma
    • Pinto-de-Sousa J, Silva F, David L et al.. Clinicopathological significance and survival influence of p53 protein expression in gastric carcinoma. Histopathology 2004; 44: 323-331.
    • (2004) Histopathology , vol.44 , pp. 323-331
    • Pinto-de-Sousa, J.1    Silva, F.2    David, L.3
  • 16
    • 77950819136 scopus 로고    scopus 로고
    • The analysis of PIK3CA mutations in gastric carcinoma and meta-analysis of literature suggest that exon-selectivity is a signature of cancer type
    • Barbi S, Cataldo I, De Manzoni G et al.. The analysis of PIK3CA mutations in gastric carcinoma and meta-analysis of literature suggest that exon-selectivity is a signature of cancer type. J Exp Clin Cancer Res 2010; 29: 32.
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 32
    • Barbi, S.1    Cataldo, I.2    De Manzoni, G.3
  • 17
    • 84855202929 scopus 로고    scopus 로고
    • Are biomarkers correlated with recurrence patterns in patients with resectable gastric adenocarcinoma
    • Li GC, Zhang Z, Ma XJ et al.. Are biomarkers correlated with recurrence patterns in patients with resectable gastric adenocarcinoma. Mol Biol Rep 2011; 39: 399-405.
    • (2011) Mol Biol Rep , vol.39 , pp. 399-405
    • Li, G.C.1    Zhang, Z.2    Ma, X.J.3
  • 18
    • 22144491262 scopus 로고    scopus 로고
    • Mutations of PIK3CA in gastric adenocarcinoma
    • Li VS, Wong CW, Chan TL et al.. Mutations of PIK3CA in gastric adenocarcinoma. BMC Cancer 2005; 5: 29.
    • (2005) BMC Cancer , vol.5 , pp. 29
    • Li, V.S.1    Wong, C.W.2    Chan, T.L.3
  • 19
    • 41649106685 scopus 로고    scopus 로고
    • How to build and interpret a nomogram for cancer prognosis
    • Iasonos A, Schrag D, Raj GV et al.. How to build and interpret a nomogram for cancer prognosis. J Clin Oncol 2008; 26: 1364-1370.
    • (2008) J Clin Oncol , vol.26 , pp. 1364-1370
    • Iasonos, A.1    Schrag, D.2    Raj, G.V.3
  • 20
    • 33644553034 scopus 로고    scopus 로고
    • Standards for reporting prognostic tumor marker studies
    • Alonzo TA. Standards for reporting prognostic tumor marker studies. J Clin Oncol 2005; 23: 9053-9054.
    • (2005) J Clin Oncol , vol.23 , pp. 9053-9054
    • Alonzo, T.A.1
  • 21
    • 70449420123 scopus 로고    scopus 로고
    • Use of archived specimens in evaluation of prognostic and predictive biomarkers
    • Simon RM, Paik S, Hayes DF. Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 2009; 101: 1446-1452.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1446-1452
    • Simon, R.M.1    Paik, S.2    Hayes, D.F.3
  • 22
    • 44249092320 scopus 로고    scopus 로고
    • Assessment of a HER2 scoring system for gastric cancer: results from a validation study
    • Hofmann M, Stoss O, Shi D et al.. Assessment of a HER2 scoring system for gastric cancer: results from a validation study. Histopathology 2008; 52: 797-805.
    • (2008) Histopathology , vol.52 , pp. 797-805
    • Hofmann, M.1    Stoss, O.2    Shi, D.3
  • 23
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for highthroughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A et al.. Tissue microarrays for highthroughput molecular profiling of tumor specimens. Nat Med 1998; 4: 844-847.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3
  • 24
    • 45949095697 scopus 로고    scopus 로고
    • HER-2/neu assessment in breast cancer using the original FDA and new ASCO/CAP guideline recommendations: impact on selecting patients for Herceptin therapy
    • Brunelli M, Manfrin E, Martignoni G et al.. HER-2/neu assessment in breast cancer using the original FDA and new ASCO/CAP guideline recommendations: impact on selecting patients for Herceptin therapy. Am J Clin Pathol 2008; 129: 907-911.
    • (2008) Am J Clin Pathol , vol.129 , pp. 907-911
    • Brunelli, M.1    Manfrin, E.2    Martignoni, G.3
  • 25
    • 84856275164 scopus 로고    scopus 로고
    • Classical lobular breast carcinoma consistently lacks topoisomerase-IIalpha gene amplification: implications for the tailored use of anthracycline-based chemotherapies
    • Brunello E, Brunelli M, Manfrin E et al.. Classical lobular breast carcinoma consistently lacks topoisomerase-IIalpha gene amplification: implications for the tailored use of anthracycline-based chemotherapies. Histopathology 2012; 60: 482-488.
    • (2012) Histopathology , vol.60 , pp. 482-488
    • Brunello, E.1    Brunelli, M.2    Manfrin, E.3
  • 26
    • 2042467574 scopus 로고    scopus 로고
    • HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a singleinstitution experience of 2,279 cases and comparison of dual-color and singlecolor scoring
    • Lal P, Salazar PA, Hudis CA et al.. HER-2 testing in breast cancer using immunohistochemical analysis and fluorescence in situ hybridization: a singleinstitution experience of 2,279 cases and comparison of dual-color and singlecolor scoring. Am J Clin Pathol 2004; 121: 631-636.
    • (2004) Am J Clin Pathol , vol.121 , pp. 631-636
    • Lal, P.1    Salazar, P.A.2    Hudis, C.A.3
  • 27
    • 0035068302 scopus 로고    scopus 로고
    • Clinical significance of mutator phenotype and chromosome 17p and 18q allelic loss in gastric cancer
    • de Manzoni G, Tomezzoli A, Di Leo A et al.. Clinical significance of mutator phenotype and chromosome 17p and 18q allelic loss in gastric cancer. Br J Surg 2001; 88: 419-425.
    • (2001) Br J Surg , vol.88 , pp. 419-425
    • de Manzoni, G.1    Tomezzoli, A.2    Di Leo, A.3
  • 28
    • 0035139644 scopus 로고    scopus 로고
    • Molecular characterization of pancreatic serous microcystic adenomas: evidence for a tumor suppressor gene on chromosome 10q
    • Moore PS, Zamboni G, Brighenti A et al.. Molecular characterization of pancreatic serous microcystic adenomas: evidence for a tumor suppressor gene on chromosome 10q. Am J Pathol 2001; 158: 317-321.
    • (2001) Am J Pathol , vol.158 , pp. 317-321
    • Moore, P.S.1    Zamboni, G.2    Brighenti, A.3
  • 29
    • 0026023833 scopus 로고
    • Median follow-up in clinical trials
    • Shuster JJ. Median follow-up in clinical trials. J Clin Oncol 1991; 9: 191-192.
    • (1991) J Clin Oncol , vol.9 , pp. 191-192
    • Shuster, J.J.1
  • 30
    • 0000336139 scopus 로고
    • Regression models and life tables
    • Cox DR. Regression models and life tables. J Royal Stat Soc 1972; 4: 187-200.
    • (1972) J Royal Stat Soc , vol.4 , pp. 187-200
    • Cox, D.R.1
  • 31
    • 0029118366 scopus 로고
    • Graphical methods for assessing violations of the proportional hazards assumption in Cox regression
    • Hess KR. Graphical methods for assessing violations of the proportional hazards assumption in Cox regression. Stat Med 1995; 14: 1707-1723.
    • (1995) Stat Med , vol.14 , pp. 1707-1723
    • Hess, K.R.1
  • 32
    • 0029621092 scopus 로고
    • Diagnostic plots to reveal functional form for covariates in multiplicative intensity models
    • Grambsch PM, Therneau TM, Fleming TR. Diagnostic plots to reveal functional form for covariates in multiplicative intensity models. Biometrics 1995; 51: 1469-1482.
    • (1995) Biometrics , vol.51 , pp. 1469-1482
    • Grambsch, P.M.1    Therneau, T.M.2    Fleming, T.R.3
  • 33
    • 63049122495 scopus 로고    scopus 로고
    • Measures to assess the prognostic ability of the stratified Cox proportional hazards model
    • Measures to assess the prognostic ability of the stratified Cox proportional hazards model. Stat Med 2009; 28: 389-411.
    • (2009) Stat Med , vol.28 , pp. 389-411
  • 34
    • 3242770671 scopus 로고    scopus 로고
    • Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation
    • Pencina MJ, D'Agostino RB. Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. Stat Med 2004; 23: 2109-2123.
    • (2004) Stat Med , vol.23 , pp. 2109-2123
    • Pencina, M.J.1    D'Agostino, R.B.2
  • 35
    • 34547152822 scopus 로고    scopus 로고
    • Maximally selected Chi-squared statistics and nonmonotonic associations: an exact approach based on two cutpoints
    • Anne-Laure B, Carolin S. Maximally selected Chi-squared statistics and nonmonotonic associations: an exact approach based on two cutpoints. Comput Stat Data Anal 2007; 51: 6295-6306.
    • (2007) Comput Stat Data Anal , vol.51 , pp. 6295-6306
    • Anne-Laure, B.1    Carolin, S.2
  • 36
    • 70350621634 scopus 로고    scopus 로고
    • A novel clinical prognostic score incorporating the number of resected lymph-nodes to predict recurrence and survival in nonsmallcell lung cancer
    • Bria E, Milella M, Sperduti I et al.. A novel clinical prognostic score incorporating the number of resected lymph-nodes to predict recurrence and survival in nonsmallcell lung cancer. Lung Cancer 2009; 66: 365-371.
    • (2009) Lung Cancer , vol.66 , pp. 365-371
    • Bria, E.1    Milella, M.2    Sperduti, I.3
  • 37
    • 0020083498 scopus 로고
    • The meaning and use of the area under a receiver operating characteristic (ROC) curve
    • Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982; 143: 29-36.
    • (1982) Radiology , vol.143 , pp. 29-36
    • Hanley, J.A.1    McNeil, B.J.2
  • 38
    • 33845382806 scopus 로고
    • Non parametric estimation from incomplete observations
    • Kaplan EL, Meier P. Non parametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457-481.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 39
    • 33750603535 scopus 로고    scopus 로고
    • Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975
    • Efficace F, Bottomley A, Smit EF et al.. Is a patient's self-reported health-related quality of life a prognostic factor for survival in non-small-cell lung cancer patients? A multivariate analysis of prognostic factors of EORTC study 08975. Ann Oncol 2006; 17: 1698-1704.
    • (2006) Ann Oncol , vol.17 , pp. 1698-1704
    • Efficace, F.1    Bottomley, A.2    Smit, E.F.3
  • 40
    • 0027081755 scopus 로고
    • A bootstrap resampling procedure for model building: application to the Cox regression model
    • Sauerbrei W, Schumacher M. A bootstrap resampling procedure for model building: application to the Cox regression model. Stat Med 1992; 11: 2093-2109.
    • (1992) Stat Med , vol.11 , pp. 2093-2109
    • Sauerbrei, W.1    Schumacher, M.2
  • 41
    • 54949117517 scopus 로고    scopus 로고
    • Logistic risk model predicting postoperative respiratory failure in patients undergoing valve surgery
    • Filsoufi F, Rahmanian PB, Castillo JG et al.. Logistic risk model predicting postoperative respiratory failure in patients undergoing valve surgery. Eur J Cardiothorac Surg 2008; 34: 953-959.
    • (2008) Eur J Cardiothorac Surg , vol.34 , pp. 953-959
    • Filsoufi, F.1    Rahmanian, P.B.2    Castillo, J.G.3
  • 42
    • 84942383855 scopus 로고
    • Modeling the severity of illness of ICU patients. A systems update
    • Lemeshow S, Le Gall JR. Modeling the severity of illness of ICU patients. A systems update. JAMA 1994; 272: 1049-1055.
    • (1994) JAMA , vol.272 , pp. 1049-1055
    • Lemeshow, S.1    Le Gall, J.R.2
  • 43
    • 76249105307 scopus 로고    scopus 로고
    • Clinical assessment of patients with advanced non-small-cell lung cancer eligible for second-line chemotherapy: a prognostic score from individual data of nine randomised trials
    • Di Maio M, Lama N, Morabito A et al.. Clinical assessment of patients with advanced non-small-cell lung cancer eligible for second-line chemotherapy: a prognostic score from individual data of nine randomised trials. Eur J Cancer 2010; 46: 735-743.
    • (2010) Eur J Cancer , vol.46 , pp. 735-743
    • Di Maio, M.1    Lama, N.2    Morabito, A.3
  • 45
    • 84982289409 scopus 로고    scopus 로고
    • Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis
    • Paoletti X, Oba K, Burzykowski T et al.. Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis. JAMA 2010; 303: 1729-1737.
    • (2010) JAMA , vol.303 , pp. 1729-1737
    • Paoletti, X.1    Oba, K.2    Burzykowski, T.3
  • 46
    • 79953311879 scopus 로고    scopus 로고
    • Gene expression signature-based prognostic risk score in gastric cancer
    • Cho JY, Lim JY, Cheong JH et al.. Gene expression signature-based prognostic risk score in gastric cancer. Clin Cancer Res 2011; 17: 1850-1857.
    • (2011) Clin Cancer Res , vol.17 , pp. 1850-1857
    • Cho, J.Y.1    Lim, J.Y.2    Cheong, J.H.3
  • 47
    • 77949263556 scopus 로고    scopus 로고
    • Prognostic significance of hostand tumor-related factors in patients with gastric cancer
    • Mohri Y, Tanaka K, Ohi M et al.. Prognostic significance of hostand tumor-related factors in patients with gastric cancer. World J Surg 2011; 34: 285-290.
    • (2011) World J Surg , vol.34 , pp. 285-290
    • Mohri, Y.1    Tanaka, K.2    Ohi, M.3
  • 48
    • 13444310428 scopus 로고    scopus 로고
    • Validation of a nomogram for predicting disease-specific survival after an R0 resection for gastric carcinoma
    • Peeters KC, Kattan MW, Hartgrink HH et al.. Validation of a nomogram for predicting disease-specific survival after an R0 resection for gastric carcinoma. Cancer 2005; 103: 702-707.
    • (2005) Cancer , vol.103 , pp. 702-707
    • Peeters, K.C.1    Kattan, M.W.2    Hartgrink, H.H.3
  • 49
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
    • Bang YJ, Van Cutsem E, Feyereislova A et al.. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010; 376: 687-697.
    • Lancet 2010 , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3
  • 50
    • 84859903908 scopus 로고    scopus 로고
    • Clinicopathologic factors associated with HER2-positive gastric cancer and its impact on survival outcomes-a systematic review
    • Chua TC, Merrett ND. Clinicopathologic factors associated with HER2-positive gastric cancer and its impact on survival outcomes-a systematic review. Int J Cancer 2012; 130: 2845-2856.
    • (2012) Int J Cancer , vol.130 , pp. 2845-2856
    • Chua, T.C.1    Merrett, N.D.2
  • 51
    • 33748595550 scopus 로고    scopus 로고
    • Topoisomerase IIalpha gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study
    • Kanta SY, Yamane T, Dobashi Y et al.. Topoisomerase IIalpha gene amplification in gastric carcinomas: correlation with the HER2 gene. An immunohistochemical, immunoblotting, and multicolor fluorescence in situ hybridization study. Hum Pathol 2006; 37: 1333-1343.
    • (2006) Hum Pathol , vol.37 , pp. 1333-1343
    • Kanta, S.Y.1    Yamane, T.2    Dobashi, Y.3
  • 52
    • 58149349981 scopus 로고    scopus 로고
    • Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients
    • Liang Z, Zeng X, Gao J et al.. Analysis of EGFR, HER2, and TOP2A gene status and chromosomal polysomy in gastric adenocarcinoma from Chinese patients. BMC Cancer 2008; 8: 363.
    • (2008) BMC Cancer , vol.8 , pp. 363
    • Liang, Z.1    Zeng, X.2    Gao, J.3
  • 53
    • 0036207042 scopus 로고    scopus 로고
    • High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer
    • Huiping C, Kristjansdottir S, Bergthorsson JT et al.. High frequency of LOH, MSI and abnormal expression of FHIT in gastric cancer. Eur J Cancer 2002; 38: 728-735.
    • (2002) Eur J Cancer , vol.38 , pp. 728-735
    • Huiping, C.1    Kristjansdottir, S.2    Bergthorsson, J.T.3
  • 54
    • 34547558483 scopus 로고    scopus 로고
    • Analysis of a panel of antibodies to APC reveals consistent activity towards an unidentified protein
    • Davies ML, Roberts GT, Stuart N et al.. Analysis of a panel of antibodies to APC reveals consistent activity towards an unidentified protein. Br J Cancer 2007; 97: 384-390.
    • (2007) Br J Cancer , vol.97 , pp. 384-390
    • Davies, M.L.1    Roberts, G.T.2    Stuart, N.3
  • 55
    • 84861613037 scopus 로고    scopus 로고
    • Microsatellite instability in sporadic gastric cancer: its prognostic role and guidance for 5-FU based chemotherapy after R0 resection
    • An JY, Kim H, Cheong JH et al.. Microsatellite instability in sporadic gastric cancer: its prognostic role and guidance for 5-FU based chemotherapy after R0 resection. Int J Cancer 2012; 131: 505-511.
    • (2012) Int J Cancer , vol.131 , pp. 505-511
    • An, J.Y.1    Kim, H.2    Cheong, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.